European Psychiatry - Volume 41 - April 2017

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S146 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S106–S169
(CBTC) circuitry. We hypothesize that the polymorphisms of the
dopaminergic pathway should be associated the abnormal CBF in
the CBTC circuitry.
Objective To investigate the association of the polymorphisms
throughout the dopaminergic pathwaywith the cerebral bloodflow
(CBF) of PMR in MDD.
Methods The blood sample of 63 patients (23 PMR, 40 NPMR)
were collected for genotyping the dopaminergic polymorphisms
(92 SNPs from10 genes). After quality controlling, 15 SNPs in 8
candidate genes were entered into the mass univariate model-
ing analysis. For the statistical analysis, patients with unqualified
fMRI image and unmatched demographic data were ruled out. Con-
sequently 56 patients (23 PMR, 33 NPMR) were taken into the
statistical analysis.
Results Genotype-by PMR associations with the CBF differences
predominately distributed in bilateral prefrontal cortex (PFC),
temporal cortex, and striatum, the left thalamus, the right pri-
mary motor cortex, insular cortex, fusiform gyri, and lingual gyri.
There were significant negative correlation between the CBF of
the PFC and the PMR severity. However, the CBF of the stri-
atum and the thalamus were positively correlated with the PMR
severity.
Conclusions The polymorphisms of dopaminergic pathway are
associated with not only CSTC circuitry, but also some other brain
regions involving in cognition and emotion controlling. While the
increased CBF of PFC might suppress PMR, the increased CBF of
striatum and thalamus adversely aggravate PMR.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
e-Poster walk: E-mental health
EW0121
The association between time spent
on computer tablets and attention
deficit hyperactivity disorder (ADHD)
among children from 3 to 12 years old
A. Alhadi ∗, O.A. Abid , K.A. Alsuhaibani , K.A. Alshehri ,
R.A. Alowaisheq , N.B. Al Backer
1 King Saud University, Department of Psychiatry, Riyadh, Saudi
Arabia
2 King Saud University, SABIC Psychological Health Research and
Applications Chair SPHRAC, Riyadh, Saudi Arabia
3 King Saud University, Department of Paediatrics, Riyadh, Saudi
Arabia
∗ Corresponding author.
Introduction ADHD is one of the most common neuropsychiatric
disorders in children. The worldwide prevalence is estimated to
be between 2–18%. The exact cause of ADHD is still unknown, but
some factors have been found to increase the risk of having ADHD
like increase TV exposure time and video games.
Objectives To study the association between time spent on com-
puter tablets (iPads or Android tablets) by children and ADHD.
Methods This cross sectional study targeted children from 3 to
12 years old who use computer tablets. Two non-random sampling
techniques were used to distribute self-administered question-
naires to one of the caregivers of 275 children, 36 of them installed
an application in their children’s computer tablets that measures
the actual time spent by the children. The questionnaire contains
demographics, validated Arabic ADHD rating scale and questions
to assess the parental attitude. The SPSS package was used for sta-
tistical analysis.
Results The results showed that the overall prevalence of ADHD
is 22.2% and it is higher in males. There is no statistically significant
association between ADHD and all variables except for the time
spent on computer tablets, which showed that children using com-
puter tablets more than the average time have an increased chance
of having ADHD with an odds ratio of 1.9 with 95% confidence
interval from 1.08 to 3.40.
Conclusion This study shows an association between time spent
on computer tablets by children and ADHD. There is need for longi-
tudinal studies to demonstrate the temporality and to confirm the
association.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0122
“Tell me more and help me to decide,
doctor” – Information seeking
attitudes and use of information
resources in patients with depression
H. Almeida ∗, M. Figueiredo-Braga
1 Hospital Magalhães Lemos, B, Porto, Portugal
2 University of Porto, Department of Clinical Neurosciences and
Mental Health Faculty of Medicine, Porto, Portugal
∗ Corresponding author.
Introduction Shared decision-making (SDM) has shown to
improve adherence, decrease hospitalization, and enhance knowl-
edge of the illness and satisfaction with mental health services.
Eliciting each patient’s preferences for information allows tailoring
the physician behavior according perspectives and expectations.
Patients with depression (PWD) have frequently limited infor-
mation regarding the availability and efficacy of psychiatric
treatments.
Aims/objectives Unveil information seeking attitudes of patients
with depression and their a priori use of digital sources of informa-
tion.
Methods A convenience sample of PWD was submitted to a bat-
tery of self-report questionnaires. Standardized instruments were
used tomeasure information seeking attitudes and the accessibility
and usage of digital information resources.
Results Thirty-six patients were inquired, with a mean age of
39.8 (13.4) years. Information-seeking preferences were high, with
an API-I score of 90.1 (13.8). Preferences for information-seeking
behaviors were higher in severely depressed (P = 0.010) and less
educated ( P = 0.026) patients. Preferences were negatively corre-
lated with length of psychiatric treatment (r =−0.514; P = 0.002).
Sixty-one percent had a priori information regarding their psy-
chiatric problem, and 68.8% considered it was influential in the
decision-making behavior. Access and use of digital resources
were correlated with education level (0.644; P = 0.000 and 0.554;
P = 0.003), age (−0.357; P = 0.001 and −0.559; P = 0.007) and illness
severity (−0.431; P = 0.04).
Conclusion Patients with depression want to be informed about
their mental condition and treatment options. Few resources are
used and decision mostly relies on health professional’s opinion
and guidance. Accessible resources seemscarce and future research
shall address the acceptance and impact of decisional-aid instru-
ments on this population.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.