European Psychiatry - Volume 41 - April 2017

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S398 25th European congress of psychiatry / European Psychiatry 41S (2017) S365–S404
EW0846
Relationship between insomnia and
tobacco smoking in
alcohol-dependent patients
A. Wnorowska ∗, A. Jakubczyk , A. Klimkiewicz , A. Mach ,
K. Brower , M. Wojnar
1 Medical University of Warsaw, Psychiatry, Warsaw, Poland
2 University of Michigan, Psychiatry, Ann Arbor, MI, USA
∗ Corresponding author.
Introduction Insomnia and tobacco use are frequent and impor-
tant problems in alcohol-dependent patients. However, the
relationship between sleep problems and cigarette smoking was
not thoroughly investigated in this population.
Aim The purpose of the study was to investigate the relationship
between tobacco smoking and severity of insomnia in alcohol-
dependent patients in treatment. We also aimed at assessing other
predictors of insomnia in this population.
Methods The study group comprised 384 alcohol-dependent
patients. Standardized tools were used to assess: tobacco depen-
dence (Fagerström Test for Nicotine Dependence [FTND]), sleep
problems (Athens Insomnia Scale [AIS]), severity of alcohol depen-
dence (Michigan Alcohol Screening Test [MAST]) and drinking
quantities before entering treatment (Timeline FollowBack [TFLB]).
Other comorbid psychiatric symptoms were assessed using Brief
Symptom Inventory (BSI) and Barratt’s Impulsiveness Scale (BIS-
11).
Results The study group included 79.1% of current smokers, 62%
of participants reported insomnia (AIS). The mean FTND score
was 6.05 ± 2.18. The multivariate regression analysis revealed
that the severity of tobacco dependence was significantly associ-
ated with the severity of insomnia (FTND, beta = 0.140, P = 0.013).
Other factors associated with insomnia that remained significant
in multivariate model were severity of psychopathological symp-
toms (BSI, beta = 0.422, P < 0.0005) and intensity of drinking (TLFB,
beta = 0.123, P = 0.034).
Conclusion Tobacco use may predict severity of insomnia in
alcohol-dependent patients. This finding may have important clin-
ical implications and influence strategies applied in treatment of
alcohol use disorders.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0847
The effect of aripiprazole on nicotine
dependency in patients under
methadone maintenance therapy
S.M. Zamir ∗, H. Javdani , A. Massoudifar , M. Naghdipour ,
A. Mehrnami
Qazvin University of Medical Sciences, Psychiatry, Qazvin, Iran
∗ Corresponding author.
Introduction The prevalence of smoking in patients under
methadone maintenance therapy is high (85–98%). Most of these
patients tend to quit smoking, but only a few of them receive treat-
ment or referred to quit smoking. Recent study on aripiprazole, has
been shown to reduce smoking.
Aims The aimof this study was to evaluate aripiprazole on smok-
ing in patients under methadone maintenance therapy.
Material and method This study was a double-blind interven-
tion study. Patients under Methadone maintenance therapy in 22
Bahman Hospital randomly divided into two intervention and con-
trol group. First with the FTQ questionnaire, nicotine dependency
assessed in all patients. Then, 6-week aripiprazole administered to
intervention group. Data were analyzed by SPSS version 21.
Results The age range of patients was 67–25 years. Two groups
were matched in demographic characteristics. Finally, mean num-
ber of FTQ questionnaire in case group before intervention was
8.9 ±1.4 and after intervention was 8.4 ± 1.6. This difference was
statistically significant (P = 0.0007).
Conclusion The study results show the aripiprazole effect in
reducing the desire to smoke in patients under methadone mainte-
nance therapy. The overall level of dependency on nicotine on the
basis of test FTQ has decreased. By choosing aripiprazole as adjunc-
tive therapy to quit smoking, by reducing the tendency of patients
to smoking, can decrease cardiovascular complications and other
problems caused by smoking and we can reduce the mortality rate
of these patients.
Keywords Methadone maintenance therapy; Aripiprazole;
Smoking; Nicotine dependency
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
e-Poster Walk: Suicidology and suicide
prevention – Part 2
EW0848
Motivations behind suicide attempts:
A study in the ER of Maggiore
hospital – Novara
D. Marangon ∗, C. Gramaglia , E. Gattoni , M. Chiarelli Serra ,
C. Delicato , S. Di Marco , A. Venesia , L. Castello , G.C. Avanzi ,
P. Zeppegno
1 Azienda Ospedaliero Universitaria, S.C. Psichiatria, Novara, Italy
2 Università del Piemonte Orientale, Translational Medicine, Novara,
Italy
∗ Corresponding author.
Introduction A previous study, conducted in the province of
Novara stated that, from an epidemiological and clinical point
of view, being a female, being a migrant, as well as being in
the warmer months of the year, or suffering from an untreated
psychiatric disease are associated with suicide attempts. Litera-
ture suggests there is a positive relation between negative life
events and suicidal behaviours. In this study, we intend to deepen
knowledge, individuating motivations and meanings underlying
suicidal behaviours. This appears a meaningful approach to inte-
grate studies and initiatives in order to prevent suicide and suicidal
behaviours.
Aim To examine possible correlation between socio-demogra-
phic and clinical characteristics andmotivations underlying suicide
attempts.
Methods Patients aged > 16 years admitted for attempted sui-
cide in the Emergency Room of the AOU Maggiore della Carità
Hospital, Novara, Italy, were studied retrospectively from the 1st
January 2015 to the 31st December 2016. Each patient was assessed
by an experienced psychiatrist with a clinical interview; socio-
demographic and clinical features were gathered. Analysis were
performed with SPSS.
Results and discussion Data collection are still ongoing; results
and implications will be discussed. We expect to find different
motivations in relation to socio-demographic and clinical charac-
teristics
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
References
[1] Zeppegno P, Gramaglia C, Castello LM, Bert F, Gualano MR,
Ressico F, et al. Suicide attempts and emergency room psy-
chiatric consultation. BMC Psychiatry 2015;15:13 [Published
online 2015 Feb 5].