European Psychiatry - Volume 41 - April 2017

514 / 916

S510 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S465–S520
EV0325
Depression and cognitive disorders in
Behc¸ et’s disease and rheumatoid
arthritis patients
D. Veltishchev ∗, T. Lisitsyna , O. Kovalevskaya , O. Seravina ,
D. Ishchenko
1 Moscow Research Institute of Psychiatry, Stress Related Disorders,
Moscow, Russia
2 Nasonova Research Institute of Rheumatology, Systemic Rheumatic
Disorders, Moscow, Russia
∗ Corresponding author.
Background Mental disorders (MD), especially depressive, have
high rates in rheumatic disorders (RD)–Behc¸ et’s Disease (BD) and
Rheumatoid Arthritis (RA). Depressive and cognitive disorders have
close pathogenesis interrelations with RD.
Objective To compare the variants of MD in BD and RA-patients.
Methods Two hundred and twenty-five (100 BD and 125 RA)
inpatients were enrolled in the study. In BD patients prevailed men
(70%) in RA–women (77%). MD were diagnosed in accordance with
the ICD-10 in semi-structured interview. For evaluation of severity
and the variants of cognitive disorders psychology and neuropsy-
chological methods were used.
Results MD were diagnosed in the majority of patients (86%),
significantly more often (P < 0001) in RA (94%) versus (vs) BD
(79%) patients. The depressive disorders dominated (BD–100%,
RA–93%). The chronic and recurrent depressive disorders prevailed
in both groups : in RA more often than in BD patients (58.4%
vs 39.2%, P = 0.003). Cognitive disorders of different severity were
diagnosed in most patients with BD and RA (73% vs 66.4%, n/s).
The mechanical memory (63%) and attention deficit (72%) in BD
and impairment of associative memory (90%) and logical thinking
(71%) in RA were the most frequent manifestations of cognitive
disorders.
Conclusion The results have shown high rates of MD, especially
chronic depression and cognitive disorders in BD and RA patients.
The necessity of interdisciplinary strategy implementation for the
improvement of individualized treatment approaches in RD has
been confirmed.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0326
Somatic symptoms, drinking, and
mental distress among Russian female
patients with rheumatoid arthritis:
A pilot study
K. Yoshimasu ∗, S. Takemura , E. Myasoedova , S. Myasoedova
1 Wakayama Medical University, Hygiene, Wakayama, Japan
2 Mayo Clinic, Health Science Research, Rochester, USA
3 Ivanovo State Medical Academy, Internal Medicine and
Endocrinology, Ivanovo, Russia
∗ Corresponding author.
Introduction Drinking has been shown to be a protective factor
against the risk of rheumatoid arthritis (RA). On the other hand, high
prevalence of depressive symptoms has been observed among RA
patients.
Objective To evaluate the association between depressive symp-
toms and somatic factors as well as drinking habits in RA patients.
Methods Drinking habits and physical symptoms in 182 female
RA outpatients in Ivanovo, Russia (average [standard deviation]
of age, 62.0 [11.7] years), were investigated. Drinking status was
classified as current drinkers (alcohol consumption within the
previous 12months) and others. Depressive symptoms were eval-
uated with MINI, HADS and CES-D questionnaires. Outcomes were
(a) presence or history of major depressive disorder, presence of
melancholic major depressive disorder, presence of dysthymia,
or 1 point or greater of suicidal risk score in MINI, (b) 8
points or greater in HADS-depression, (c) 8 points or greater in
HADS-anxiety, and (d) 16 points or greater in CES-D. Stepwise
logistic regression was used to evaluate somatic factors associ-
ated with depressive symptoms, with age and drinking status
included.
Results Drinking was rather protective against depression, but
did not reach statistical significance. Symptomatic parts in the
extremities associated with the outcomes were shoulders for
MINI, elbows and knees for HADS-depression, shoulders for HADS-
anxiety, and hands, elbows and shoulders for CES-D. In the stepwise
selection, some symptoms in the extremities were positively asso-
ciated with the outcomes.
Conclusion Symptoms chiefly in large joints contributed to
depressive symptoms.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0327
Long-term validation of the SAD
PERSONS scale for prediction of repeat
self-harm in A&E patients with and
without a prior self-harm history
Y. Zakaria∗, A. Mitchell
University of Leicester, Psychiatry, Leicester, United Kingdom
∗ Corresponding author.
Objective Repeated self-harm is difficult to predict particularly
in the long-term. Scales that help identify risk of repetition are
widely used, and the most popular is the modified SAD PERSONS
scale (mSPS). We aimed to clarify the accuracy of the mSPS in first
time and non-first time patients presenting with self-harmwith an
extended follow-up period of observation.
Method We conducted the UK’s first long-term prospective risk
prediction study of patients to an Accident and Emergency (A&E)
department. We followed up 774 patients for a mean period of
7.4 years. At the time of study 429 patients presented with their
first episode of self-harm and 345 had a hospital record of past
history of self-harm.
Results During 7.4 years of follow-up 54.7% of those who ini-
tially presentedwith self-harmrepresentedwith a repeat self-harm
episode. Four hundred and twenty-one patients had a mSPS score
less than 6 (low risk), 260 had a score between 6 and 8 (mod-
erate risk) and 94 scored 9 or higher usually notated as high
risk. The clinical utility of the mSPS was “poor” for predicting
future self-harm but at cut-offs ≥7 it was “fair” for predicting
non-repetition. Of the individual questions in the mSPS, a pos-
itive answer to “stated future wishes” was a true positive in
74.0%.
Conclusions We found themSPSwas a relatively poor indicator of
future self-harm risk in a long term follow-up of patients who self-
harmed regardless of hospital record of previous self-harm history.
However,mSPS didhavemodest value inpredicting non-repetition.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.