European Psychiatry - Volume 41 - April 2017

648 / 916

S644 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S583–S644
(BAI), Beck Depression Inventory (BDI), dissociative experiences
scale, 20-item Somatoform dissociation questionnaire and shee-
han disability scale before treatment, and with subjective Y-BOCS,
objective and subjective CGI, BAI and BDI at the end of treatment.
Patients were treated with antidepressants and daily intensive
group CBT for six weeks.
Results During 6-week intensive CBT program in combination
with pharmacotherapy, there was significant improvement in
patients suffering from OCD resistant to drug treatment. There
were statistically significantly decreased scores of scales assessing
severity of OCD symptoms, anxiety, and depressive feelings. A
lower treatment effect was achieved specifically in patients who (a)
showed fewer OCD themes in symptomatology, (b) showed higher
level of somatoform dissociation, (c) had poor insight and (d) had a
higher initial level of overall severity of the disorder. Remission of
the disorder was more likely in patients who (a) had good insight,
(b) had a lower initial level of anxiety and (c) had no comorbid
depressive disorder.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0737
Application of cognitive-behavioral
therapy in a case of
obsessive-compulsive disorder
L. Rodríguez Andrés ∗, A. Rodriguez Campos , I. Sevillano Benito ,
H. De la Red Gallego , C. Noval Canga , P. Marques Cabezas ,
F. Uribe Ladron de Cegama
Hospital Clinico Universitario de Valladolid, Psychiatry Department,
Valladolid, Spain
∗ Corresponding author.
We present the case report of a 46-year-old woman who expe-
rienced obsessive-compulsive symptoms for over twenty years,
with multiple relapses, severe depressive symptoms and many
hospitalizations in the psychiatric Inpatient Unit. Treatment with
different SSRIs, tricyclic antidepressants, atypical antipsychotics
and even electroconvulsive therapy were administered with poor
results.
After her last hospitalization a Cognitive-Behavioral Therapy,
including exposure and response prevention and cognitive ther-
apy, is initiated combined with medication, improving depressive
symptoms, the ritual behaviors and levels of anxiety.
Modern treatments for Obsessive-Compulsive Disorder (OCD) have
radically changedhowthe disorder is viewed.While in the past OCD
was regarded as chronic and untreatable, a diagnosis of OCD may
now be regarded with hope. Cognitive and behavior therapy and
antidepressantmedications are currently used to treat the disorder.
They can be used to control the symptoms and enable people with
OCD to restore normal function in their lives.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0738
Misophonia: Case report
C. Vidal ∗ elo Vidal J. Alvarenga Lage
1 faculdade de medicina de barbacena, psiquiatria, Barbacena, Brazil
2 Barbacena Medicine School, student, Barbacena, Brazil
∗ Corresponding author.
Introduction Misophonia refers to a condition in which there is
a strong aversion to certain sounds, in response to it the person
reports unpleasant emotional experiences and autonomic arousal.
Objectives To present the case of misophonia carrier and discuss
diagnostic features.
Methodology Case report and literature review.
Results Female, 32 years old, married, two children. In anam-
nesis reported obsessional symptoms (Check doors and windows,
concerned with order and symmetry of objects; read all that lies
ahead, pull the hand two or three times on mobile) since ado-
lescence. Also reported triggering situations of anger: intolerance
to some noises and sounds, like chewing third, mobile keyboard,
click the “mouse” computer, printer and rub hands. In the pres-
ence of these noises, she tries to move away, and already tried
to attack physically relatives and insulting co-workers. She was
treated with escitalopram and re-evaluation after thirty days,
reported partial relief misophonia and reduction of obsessional
symptoms.
Conclusion The conditionwas first described in the early 2000s by
two audiologists, and has become the focus of interest in the field of
psychiatry. Some reports suggest that misophonic symptoms may
be part of other conditions such as Tourette’s syndrome, obsessive
compulsive disorder and generalized anxiety disorder. Specifically,
the characteristics shared between misophonia and OCD, as the
relief of discomfort associated with avoidance behaviour suggest
that the condition is part of the obsessive-compulsive spectrum,
which seems to happen with the case described above.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.