European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S583–S644 S641
Objectives We aim to expose the possible organic etiology of a
hoarding disorder case with atypical presentation.
Materials and methods We present a case of a 48 years old male
patient who was brought to the hospital by the police after being
reported for unhealthy conditions in his home. In the home visit
paid by the Social Services an excessive hoarding of objects and
trash was detected. A possible hoarding disorder was diagnosed in
the psychiatric assessment. Among other diagnostic test, a brain
CT was conducted, in which a frontal meningioma was iden-
tified. After surgical treatment, hoarding symptoms diminished
significantly.
Discussion A significant part of the hoarding disorders are
attributed to primary psychiatric disorders, resulting in potentially
treatable organic pathology going unnoticed.
Conclusion It’s important to rule out organic etiology before
proceeding to make a definitive hoarding disorder diagnosis, opti-
mizing that way the treatment options.
Keywords Hoarding; OCD; Meningioma
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0728
Knowledge takes up space, a family
affair
L. Garcia Ayala ∗, M. Gomez Revuelta , C. Martin Requena ,
M. Juncal Ruiz , O. Porta Olivares ,
E. Saez de Adana Garcia de Acilu , A. Aranzabal Itoiz ,
B. Gonzalez Hernandez , M. Laborde Zufiaurre ,
M.P. Lopez Pe˜na , N. Nu˜nez Morales , M. Zubia Martin ,
A.M. Gonzalez-Pinto Arrillaga
1 Osakidetza, Psychiatry, Salvatierra-Agurain, Spain
2 Osakidetza, Psychiatry, Vitoria, Spain
3 Marqués de Valdecilla, Psychiatry, Santander, Spain
∗ Corresponding author.
Introduction Previous research suggests that hoarding aggre-
gates in families and is associated with health, safety risks and
family problems. Hoarding symptoms appear to be more common
among first-degree relatives of people who hoard. A predominance
of shared hoarding disorder has been observed among female rela-
tives.
Objectives We present an atypical case report describing hoard-
ing symptoms among first-degree male relatives who present two
different subtypes of hoarding disorder.
Materials and methods We report the case of a 38 years old
male patient, attended for the first time by the mental health ser-
vices at the age of 22, and being diagnosed of severe OCD at that
moment. In the home visit paid by the social services, an exces-
sive object hoarding was observed, including the presence of over
40,000 books.
Moreover, they found a 38 years old man looking severely dete-
riorated; when they ask him about it, the patient’s father admits
to having been isolated in the house for almost 14 years. Hoarding
history was gathered, through the acquisition of various objects by
the patient’s father, dating back to over 30 years ago.
Discussion The harmonic coexistence for over a decade between
two patients affected with a hoarding disorder with two different
clinical setting subtypes was only made possible by the comple-
mentary nature of their symptoms.
Conclusion The hoarding disorders amongst more than one per-
son living under the same roof are uncommon, can present
themselves in both genders and can exhibit different symptoms.
Keywords Hoarding; OCD; Genetics
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0729
About a case suicide attempt as
a trigger of remission in obsessive and
compulsive disorder
J.M. Gota Garcés ∗, R. García Lopez , A. Porras Segovia ,
J.E. Mu˜noz Negro , J. García Jiménez , L. Gutierrez Rojas
Hospital Campus de la Salud, Salud Mental, Granada, Spain
∗ Corresponding author.
Introduction This is the case of a 73 year old woman with a
late onset, severe and refractory obsessive-compulsive disorder
who experimented a sudden remission after a frustrated suicide
attempt.
Objective Our target is to make a reflection about the relation
between traumatic closeness to own death and neurosis sponta-
neous remission.
Method Patient has been interviewed and her medical record
studied.
Results Patient’s psychiatric history shows major depressive
disorder, recurrent (ICD 10 CM-F33). Patient is a housewife
with primary education. In her psychobiography distinguish a
conflictive relationship which probably acted as a trigger for
obsessive-compulsive symptoms. These symptoms include obses-
sive thoughts of contamination, ritual hand washing and avoid
contact with others people. In the course of the last 10 years,
since the OCD (ICD 10 CM-F42.2) diagnose, the patient has been
through a wide therapeutic arsenal, from cognitive-behavioural
psychotherapeutic interventions to psychopharmacological treat-
ment, resulting with limited effectiveness. The last treatment was
fluoxetine 200mg (0–0–1) and pregabalin 300mg (1–0–1). Subse-
quently, the patient underwent a failed suicide attempt by hanging.
After physical recovery, all OCD symptoms had subsided.
Conclusions Traditionally, literature and philosophy consid-
ered catharsis as a purifying experience, and Breuer and Freud
introduced this concept in modern psychology as a therapeu-
tic method. More recent authors as Yalom have correlated the
closeness to death as a stress factor with radical change in life’s
perspective and attitude. Although current research presents con-
tradicting data about healing effectiveness through a catharsis
processes, this case exposes a clear example of positive outcomes
in this assumption.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0730
Adenylate-cyclase activity in
obsessive-compulsive patients
D. Marazziti ∗, S. Baroni , F. Mucci , L. Palego , A. Piccinni
University of Pisa, Dipartimento di Medicina Clinica e Sperimentale-
Section of Psychiatry, Pisa, Italy
∗ Corresponding author.
Introduction A possible role of second messengers, such as cyclic
adenosine monophosphate (cAMP) signalling, in the development
of obsessive-compulsive disorder (OCD) has been recently postu-
lated.
Aims The aimof the present studywas to explore and to compare
the adenylate cyclase (AC) activity in both basal conditions and after
the stimulation by isoprenaline (ISO) in platelets of OCD patients
and healthy control subjects. The AC activity was measured both
in the absence and in the presence of - and - adrenoreceptor
antagonists.
Materials and methods Forty patients were included in the study
and compared with healthy volunteers. Biological assays were car-
ried out with a method developed by us.
Results The basal AC activitywas similar in both groups. The addi-
tion of 10 M ISO enhanced significantly (P< .05) platelet basal AC