European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S106–S169 S137
Material and methods PAFIP is an early intervention program
for early stages of psychosis. One hundred and sixty-three were
included, followed-up at regular intervals of six months for three
years with administration of clinical and functional scales (BPRS,
SAPS, SANS, CDRS, GAF and Drake). Patients were divided into
three groups: (1) those non-users neither before the onset nor
during follow-up (nn) PEP, (2) consumers before the FEP and dur-
ing follow-up (ss) and (3) consumers before the FEP that gave up
consumption during follow-up (sn).
Results No statistically significant differences were observed in
terms of functionality at three-year follow-up endpoint but a
trend to a better-preserved functionality in the sn group. The sn
group presented lower scores in scales for positive symptoms with
respect to the comparison groups.
Conclusions The interruption in cannabis use may have a bene-
ficial effect on short-term clinical prognosis and functionality on
long term.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0094
Dual diagnosis and medical
co-morbidity: Data from a specialized
brief psychiatric in-patient unit
M. Gomez Revuelta ∗, M. Juncal Ruiz , O. Porta Olivares ,
L. Sanchez Blanco , D. Abejas Diez ,
G. Pardo de Santayana Jenaro , R. Landera Rodriguez ,
N.I. Nu˜nez Morales , L. Garcia Ayala
1 Hospital Universitario de Álava-Sede Santiago, Vitoria-Gasteiz,
Psychiatry, La Penilla, Spain
2 Hospital Universitario Marques de Valdecilla, Psychiatry,
Santander, Spain
3 Hospital Universitario de Álava-Sede Santiago, Psychiatry,
Vitoria-Gasteiz, Spain
∗ Corresponding author.
Introduction Previous research on the prevalence of medical
disorders among adults with dual diagnosis (DD) has been incon-
clusive.
Objectives The purpose of this study was to assess dual diagnosis
and medical co-morbidity at the Brief Psychiatric Inpatient Unit
of Marqués de Valdecilla Hospital, Santander in the period from
January 2014 until March 2015.
Methods Ninety-three patients were admitted at our hospital
from December 2014 until March 2015. The simple was analyzed
retrospectively. Sixty-two of the patients (66.7%) met criteria for
Dual Diagnosis. We collected socio-demographic variables, drug
abuse, mental pathology, and treatment received.
Results The mean age of the sample was 42.95 years (± 14 DS)
with a male:female ratio of 1.8:1 (no significant differences by
gender). Hypertension was more prevalent among patients with-
out dual pathology (22.5%). Patients with dual diagnosis presented
hypertension less likely (6.5%) (P < 0.005). This can be explained by
the fact that patients without dual diagnosis had a higher mean
age (47 years) than patients with dual diagnosis (42 years). We did
not found statistically significant differences between both groups
respect to diabetes mellitus, vascular brain disease, HIV and dys-
lipidemia.
Conclusions Hypertension was less likely to appear among
patients with dual pathology admitted to an ultra brief psychiatry
unit. This could be explained for an earlier mean age at admission
among these patients.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0095
The association between autistic traits
and post-traumatic stress disorder:
Preliminary findings among
typically-developing adults in Israel
D. Horesh∗, N. Haruvi-Lamdan , S. Lebendiger , O. Golan
Bar Ilan University, Psychology, Ramat Gan, Israel
∗ Corresponding author.
Background and aims Although studies show that those suffer-
ing from autism spectrum disorders (ASD) face an increased risk
of exposure to trauma (bullying, physical abuse), the co-morbidity
between autistic symptoms/traits and post-traumatic stress disor-
der (PTSD) was almost entirely neglected by researchers. The aim
of this preliminary study is to explore the possible associations
between these two conditions among typically-developing college
students.
Methods Participants were 39 students, recruited from 2 Israeli
universities. Twenty-four participants were psychology students,
and 15 were business administration students. Participants
completed self-report questionnaires tapping sociodemographic
background, trauma exposure, PTSD (the PTSD Checklist-5, PCL-5),
and autistic traits (the Autism Spectrum Quotient, AQ).
Results Our preliminary findings revealed a positive association
between symptoms of PTSD and autistic traits. More specifically,
among those in the 3rd and 4th highest quartiles of AQ scores,
87.5% met the cut-off score for a probable PTSD diagnosis ( 2
(3) = 8.25, P < 0.05). In addition, t-tests comparing the PTSD and
non-PTSD groups showed significant differences in 3 out of 5 AQ
sub-scales: social skill (t(37) = –2.12; P < 0.05), attention switch-
ing (t(37) = −2.09; P < 0.05) and communication (t(37) = −2.80;
P < 0.01). Thus, higher AQ scores were reported by those in the PTSD
group.
Conclusions ASD may serve as a significant risk factor for post-
traumatic symptomatology. The associations between these two
conditions may be mediated by a variety of potential shared vul-
nerabilities, including increased rumination, dysregulated emotion
and impaired social cognition. Further research is needed in order
to explore these mechanisms, as well as to assess co-morbidity in
clinical samples of both ASD and PTSD.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0096
Diet and physical activity intervention
effectiveness in acute mental patients,
during hospitalization: A matched
case-control study
J. Isaac ∗, S. Guerreiro , C. Pinheiro , A. Pardal , N. Correia ,
S. Simões Dias , C. Santos , A. Matos Pires
1 ULSBA, Psychiatry and Mental Health Department, Beja, Portugal
2 ULSBA, Pharmacy, Beja, Portugal
3 ULSBA, Nutrition, Beja, Portugal
4 Escola Superior de Saúde de Leiria, Instituto Politécnico de Leiria,
UIS, Unidade de Investigac¸ ão em Saúde, Leiria, Portugal
∗ Corresponding author.
Introduction Diet and physical activity interventions are effective
in psychiatric outpatients that suffer from obesity, namely those
treated with antipsychotic drugs. However, there is less evidence
related to these interventions in hospitalised acute patients.
Aim To evaluate the effect of a diet and physical activity program
on weight and BMI variation in acute psychiatric patients during
hospitalisation.
Methods Matched case-control study from January to September
2016. Inclusion criteria: patients with at least 15 days of hospitali-