European Psychiatry - Volume 41 - April 2017

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S138 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S106–S169
sation in an acute psychiatryward, evaluated by a nutritionist in the
admission and medical discharge. The intervention consisted in a
diet and physical activity program, with total restriction to visitors
to bring food to the patients. Statistical analysis was done with T-
student andmultiple linear regression taking into account the effect
of age, sex, daily dose of antipsychotics, and days of hospitalisation.
Results Sixty-six patients were studied (34 cases and 32 con-
trols). Groups were statistically similar concerning the average of
age, daily dose of antipsychotics, days of hospitalisation and sex.
The differences of weight gain during hospitalisation were 0.088 kg
(cases) versus 1484 kg (controls), P < 0.05. And the differences of the
increased BMI during the hospitalisation were 0.041 kg/m2 (cases)
versus 0.509 kg/m 2 (controls), P< 0.05.
Conclusions Obesity presents challenging health problems for
individuals with severe mental illness that require inpatient treat-
ment. This study provides evidence that individuals with acute
mental illness can benefit from weight control interventions dur-
ing their hospitalisation, in special a total restriction to visitors to
bring food to the patients.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0097
Update and revision of the RANZCP
clinical practice guidelines for mood
disorders
M. Hopwood
The Royal Australian and New Zealand College of Psychiatrists,
OPCEO, Melbourne, Australia
In 2015, the Royal Australian and New Zealand College of Psy-
chiatrists (RANZCP) published its new Clinical Practice Guidelines
(CPGs) for Mood Disorders. The Mood Disorder CPG focuses on
‘real world’ clinical management of depressive and bipolar dis-
orders, addressing mood disorders as a whole to recognise the
overlap between distinct diagnoses and changes in diagnoses along
the mood disorder spectrum. This presentation will provide an
overview of the process andmethodology used in the development
of the guidelines, aswell as the key principles established in the new
CPG for the assessment and management of depressive and bipolar
disorders.
Disclosure of interest The author has not supplied his/her decla-
ration of competing interest.
EW0098
Psychiatry’s and psychiatrists’
contract with society
B. Janse van Rensburg
University of the Witwatersrand, Psychiatry, Johannesburg, South
Africa
Introduction TheWorld Psychiatric Association (WPA) is aworld-
wide association of national psychiatric associations, aiming to
increase knowledge and skills necessary for work in the field of
mental health and care of the mentally ill. It was suggested that
Psychiatry’s relationship with society should be seen as a contract
his implicit understanding usually specifies the scope, princi-
ples, quality and outcome of this agreement. It also implies a series
of reciprocal rights and duties, privileges and obligations, as well
as expectations from both sides.
Aim To investigate the extent of existing social contracting of
WPA Member Associations (MAs) and WPA structures regarding:
– communities they serve;
– general public;
– medical institutions;
– other practitioner groups in the multidisciplinary team;
– administrations, managers and funders.
Objectives Include to describe the current scope of psychiatric
practice across WPA regions and the content of existing social con-
tracts.
Methods Amixed–methods, explorative, descriptive, theory gen-
erating inquiry, with different phases, including a systematic
review of literature and WPA documentation, electronic ques-
tionnaires to MAs and focus group discussions with WPA ZS
chairs/representatives.
Results MA profiles and progress indicators were identified and
summarised. A transcription of group discussions was made, while
pertaining documents, questionnaires and in depth/focus group
interview content was analysed.
Conclusions This presentation will report on progress with this
study to date.
Disclosure of interest The author has not supplied his/her decla-
ration of competing interest.
Reference
[1] Bhugra D. Introduction. In: Bhugra D, Malik A, Ikkos G, editors.
Psychiatry’s Contract with Society: Concepts, controversies and
consequences. Oxford: Oxford University Press; 2011.
e-Poster walk: Depression–part 1
EW0099
Effect of electroconvulsive therapy on
serum serotonin level in patients with
treatment–Resistant major depressive
disorder
P. Agha Mohammad Hasani ∗ Mokhtaree M. Fatemeh
N. Mohammad
1 Rafsanjan university of medical sciences, Psychiatry, Rafsanjan, Iran
2 Rafsanjan university of medical sciences, laboratory sciences,
Rafsanjan, Iran
∗ Corresponding author.
Background This study aimed to determine the effect of Electro-
convulsive Therapy (ECT) on serum serotonin level of patients with
major depressive disorder (MDD).
Methods In this experimental study, 36 patients (age: 20–65
years old) with MDD were allocated to ECT group ( n = 21) and non-
ECT group (n = 15). Serum serotonin level of the ECT group was
measured before ECT, 15minutes and two, six, and 24 hours after
the first session, and 24 hours and 30 days after the last ECT session.
Measurements were performed at the time of admission and one
month after hospitalisation in the non-ECT group. Data analysed
with t-tests, repeated measures analysis of variance by SPSS16.
Results The mean serotonin levels of the two groups were signif-
icantly different 24 hours and 30 days after the last session of ECT
(P = 0.048 and P = 0.04, respectively). The difference of mean sero-
tonin levels in the ECT group before & 15min after ECT (P = 0.044)
before & 6 hour after ECT ( P = 0.015), before & 24 hour after ECT
(P = 0.007), before & 24 hour after last ECT (0.002) was meaningful.
Conclusion Altogether, our results showed that serum serotonin
levels significantly increase following ECT in MDD patients.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.