European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S303–S364 S313
costs for patients in the “chronic high” and “worsening” class were
significantly higher, as compared to the “stable low” class.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0605
Incidences and risk factors of severe
infections in young adults with
schizophrenia: A nationwide
register-based cohort study in
Denmark
M. Pankiewicz-Dulacz∗, E. Stenager , E. Stenager , M. Chen
University of Southern Denmark, institute of regional health services
research, Odense C, Denmark
∗ Corresponding author.
Introduction Patients with schizophrenia deal with many risk
factors that make them more susceptible to infections. However,
knowledge about incidence and the nature of infections among
people with schizophrenia is scarce.
Aims To investigate the occurrence and risk factors for severe
infections in schizophrenia patients.
Objectives – to determine incidence rates of infections among
young adults with schizophrenia;
– to define risk factors for infections.
Method Population-based nationwide cohort study with selec-
tion of all individuals born in Denmark between 1975–1990 and
follow-up period from 1995–2013 was conducted. Data from the
Danish Psychiatric Central Register and the Danish National Hospi-
tal Registrywere used. A Poisson regressionwas chosen to estimate
incidence rate ratios of infections and to explore the associations
of different risk factors like sex, age, substance abuse and medical
co-morbidity with the rates of infections.
Preliminary results 922,564 individuals born between
1975–1990 were included in the study. Overall, 3520 women
and 5479 men were identified with schizophrenia. In percentages,
36% with schizophrenia had infectious diseases compared to 25%
of background population. Some of severe infections like HIV
(0.23% vs 0.05%), sepsis (0.72% vs 0.27%), hepatitis (1.4% vs 0.22%)
skin infections (12% vs 6.2%)and tuberculosis (0.12% vs 0.06%) were
highly increased in persons with schizophrenia, whereas smaller
differences were found regarding CNS infections (0.5% vs 0.4%) and
gastrointestinal infections (8.7% vs 6.2%).
Conclusions The preliminary data results suggest, that indivi-
duals with schizophrenia have higher prevalence of all types of
severe infectious compared to the background population.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0606
Prevalence of depression and anxiety
in patients with chronic
non-malignant pain–A Danish
register-linkage cohort study
S. Søndergård ∗ . Vægter rlangsen tenager
1 Institute for regional health services, university of Southern
Denmark, research unit in mental health, Aabenraa, Denmark
2 Pain Centre South-Odense university hospital, pain research group,
Odense, Denmark
3 Faculty of health science, university of Southern Denmark,
department of clinical research, Odense, Denmark
4 Danish research institute for suicide prevention, mental health
centre Copenhagen, Copenhagen, Denmark
∗ Corresponding author.
Introduction Anxiety and depression disorders are common in
patients with chronic pain. Studies using clinical interviews in
patients with chronic pain report prevalence rates ranging bet-
ween 30–54% for depression and 17–29% for anxiety. This is the
first study using contacts with a hospital psychiatric ward to inves-
tigate prevalence of depression and anxiety in patientswith chronic
pain.
Objectives Estimate the prevalence of anxiety and depression in
patients with chronic pain referred for interdisciplinary treatment.
Aims To increase the knowledge about mental disorders and
chronic pain in secondary health care.
Methods All chronic pain patients referred to and treated at an
interdisciplinary pain clinic at Odense university hospital, Denmark
from 1 Jan 2005–13 Nov 2015 were included as participants. The
Danish National Patient Register was used to collect information
on contacts with a hospital psychiatric ward 10-year prior to the
first contact at the pain clinic due to depression (ICD-10: F32-F33)
and/or anxiety (ICD-10: F40-F41).
Results In total, 7204 patients (64% women; mean age: 48.2)
were included. Altogether, 17.8% (95% CI: 16.9–18.7) of patients had
contact to a psychiatric ward. The prevalence of unipolar depres-
sionwere: 6.1% (95% CI: 5.5–6.6) and anxiety: 2.1% (95% CI: 1.8–2.5),
while 0.7% (95% CI: 0.5–0.9) had both depression and anxiety.
Conclusions The prevalence rates of depression and anxiety
noted in this study were lower than those reported in previous
studies. A hospital-based diagnosis seems likely to be less frequent
than interview-based measures, yet, might have a higher validity
due to the clinician-based assessment.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0607
Psychosomatic and
psychopathological paradigms of
alcoholic anorexia
I. Sosin ∗ huev , O. Goncharova , G. Misko , A. Volkov
Kharkov medical academy of postgraduate education, narcology,
Kharkov, Ukraine
∗ Corresponding author.
Introduction Alcoholic anorexia (AA), being one of prevalent nar-
cology diseases, up to now has not been studied in psychosomatics
and psychopathology paradigm.
Aims and objectives To identify multifactorial pathopsycho-
logical, psychopathological, nervous, alimentary, toxicological
constituents of AA pathogenesis.
Method Twenty-four patients with alcohol dependence (males
aged 29–37) have been studied. Diagnosis was objectified by psy-
chosomatic, pathopsychological complex international valid tests
and rating, adequate for investigation design, laboratory, electro-
physiology, biochemical, ultrasound and other methods.
Results AA was accompanied with mental and physical post-
intoxication exhaustion, asthenizing, tremor, dissomnia, depres-
sion, pre-delirium signs. Psychosomatic concept was proposed
for reasonable identification of intranosological AA clinical forms
in narcological clinical course. Anorectic dipsomaniac conditions
are explained pathogenetically with psychosomatic mechanisms
of deviant addictive craving behaviour as pathopsychological tar-
get and patient’s intentional complete or partial refuse food
consumption in favour of real in time more quick and brutal
attainment of alcoholic drunkenness (Ebrietas Alcogolica). This
anorexia fabula draws AA closer to Anorexia Nervosa and mostly
reflects compulsive obsession with alcohol use. Pathopsychologi-
cal, psychosomatic, neurogenousmechanisms of alcoholic anorexia
of drinking bout early stages are transformed gradually to post-
intoxication alimentary, nervous, psychic exhaustion. Meanwhile,