European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S303–S364 S311
Results Statistically significant differences between groups were
observed. The consumers group (ss + sn) had an earlier age of onset,
most were male, unemployed, single, prone to loneliness and they
were concomitant users of alcohol and tobacco.
Conclusions The use of cannabis has a detrimental effect on
the outcome of schizophrenia. A specific and early intervention
could contribute to prognostic improvements. Identifying cannabis
consumption subtypes could be useful for this purpose.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0599
Association between ADHD and
psychopathy among inmates in a
high-security prison in Portugal
D. Loureiro ∗, A. Machado , T. Silva , T. Veigas , J. Cerejeira
1 Centro hospitalar e universitário de Coimbra, psychiatry, Coimbra,
Portugal
2 Universidade de Coimbra, medicine faculty, Coimbra, Portugal
∗ Corresponding author.
Introduction ADHD is associatedwith psychopathic traits, both in
the general population and in perpetrators, due to the impulsivity,
but not the affective component of psychopathy.
Objectives To analyze this relationship among a sample of
inmates from a high-security male prison, using an instrument that
further divides the callous-unemotional factor of psychopathy into
boldness and cruelty, and see if they relate to ADHD independently
from the impulsivity/disinhibition.
Methods One hundred and one subjects aged 18–65, with at
least 4 years of formal education, were interviewed for socio-
demographic data and completed the ASRS-v1.1 (Adult ADHD
Self-Report Scale) and the TriPM (Triarchic Psychopathy Measure).
Subjects were divided into ADHD positive or negative according to
their score in the ASRS-v1.1, and then compared regarding TriPM
score (total, disinhibition, boldness and cruelty) using Student’s t-
test. Linear regression was used to assess independency between
the subscales of TriPM.
Results Seventeen subjects scored positive for ADHD. They
significantly differed from the non-ADHD group regarding all psy-
chopathy scores (total, t = −5.03, P < 0.0001; disinhibition, t = −3.53,
P = 0.0006; and cruelty, t = −4.96, P < 0.0001), except for boldness
(t = 1.97, P= 0.005). The cruelty score is independent from boldness
(R2 = 0.03) but not from the disinhibition score (R2 = 0.24). Disinhi-
bition and boldness are also unrelated (R2 = 0.01).
Conclusions In line with previous work, our study shows a strong
association between ADHD and psychopathy, with both condi-
tions sharing the disinhibition/impulsivity factor. Although ADHD
subjects score higher for cruelty, this isn’t independent from disin-
hibition, and may be a result of them being more prone to admit to
cruel behaviours, due to deficient response inhibition.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0600
Novel psychoactive substances in a
psychiatric young adults sample:
A multicenter, observational study
M. Lupi ∗, T. Acciavatti , S. Marini , E. Cinosi , R. Santacroce ,
M. Corbo , V. Mancini , T. Galanti , M. Carlucci , G. Martinotti ,
M. Di Giannantonio
University “G. D’Annunzio”, department of neuroscience and
imaging, Chieti, Italy
∗ Corresponding author.
Introduction Comorbidities between psychiatric diseases and
consumption of traditional substances of abuse are common.
Nevertheless, there is no data regarding the use of novel psychoac-
tive substances (NPS) in the psychiatric population.
Objectives The purpose of this multicentre survey is to investi-
gate the consumption of a wide variety of psychoactive substances
in a young psychiatric sample.
Methods Between September 2013 and November 2015, a ques-
tionnaire has been administered, in ten Italian psychiatric care
facilities, to a sample of 671 psychiatric patients (48.5% men; 51.5%
women), aged between 18 and 26 years (mean age: 22.24).
Results 8.2% of the sample declared use of NPS at least once
in a lifetime and 2.2% have assumed NPS in the last three
months. The NPS more used were synthetic cannabinoids (4.5%),
followed by methamphetamine (3.6%). The three psychiatric diag-
nosis with more frequent NPS consumption were bipolar disorder
(23.1%), personality disorders (11.8%) and schizophrenia and rela-
ted disorders (11.6%). Bipolar disorder was associated with NPS
consumption (P < .001). Among the illicit drugs investigated, 31.4%
of the sample was cannabis smoker and 10.7% cocaine user. Moreo-
ver, 70.6% of the sample declared alcohol use and 47.7% had binge
drinking conducts. In univariate regression analysis, bipolar disor-
der was positive associated with binge drinking while obsessive
compulsive disorder resulted negative associated.
Conclusions The use of novel psychoactive substances in a young
psychiatric population appears to be a frequent phenomenon, pro-
bably still underestimated. Bipolar disorder shows an association
with NPS use. Therefore, careful and constant monitoring and accu-
rate evaluations of possible clinical effects related to their use are
necessary.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0601
Personality traits and tobacco
smoking among male alcoholics with
secondary depression
G. Mandic-Gajic ∗, M. Dolic , A. Eror , Z. Spiric
Military medical academy, psychiatry clinic of psychiatry, Belgrade,
Serbia
∗ Corresponding author.
Introduction After alcohol withdrawal, secondary depression
may persists and might be a risk factor for relapse among primary
alcoholics.
Objectives The differences between male alcoholics with secon-
dary depression (D) and without depression (wD) regarding the
personality dimensions and tobacco smoking were explored.
Aims The aim was to investigate risk factors for secondary
depression.
Methods One hundred male primary alcoholics were recrui-
ted during inpatient treatment, and 86 completed the study.
The assessment of depression by Hamilton Depression Rating
Scale - HAMD (Hamilton, 1960), the pattern of cigarette use and
personality dimensions assessment by Eysenck personality ques-
tionnaire – EPQ (Eysenck & Eysenck, 1975) were performed for all
participants on admission. After four weeks according HDRS cut off
score, theywere divided intoDgroup (n = 43) andwD (n = 43) group.
The differences between groups were tested by Student t-test and
Pearson’s correlation test was applied.
Results The personality traits showed difference between D
and wD alcoholics’ subgroups for neuroticism 15.07 ±4.89 vs.
10.37± 4.40 (P < 0.01) and for extraversion 11.74± 5.05 vs.
14.30± 4.24 (P< 0.05) respectively. The positive correlation bet-
ween the mean HDRS score and neuroticism (r = 0.487, P< 0.001),
without significant correlation between other EPQ dimensions and