European Psychiatry - Volume 41 - April 2017

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S316 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S303–S364
– evaluation of mental and physical status;
– distinguishing the nosological groups;
– choice of therapy;
– formation of groups of observation (risk groups in need for course
therapy, systematic therapy).
Conclusion Consultation liaison psychiatry in general medical
institution allows widening accessibility of psychiatric care and
makes its provision more cost-effective.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0614
Psychopathological aspects of
appearance dissatisfaction in
aesthetic medicine
V. Medvedev ∗, V. Frolova , V. Vissarionov
1 PFUR university, chair of psychiatry-psychotherapy and
psychosomatic pathology, Moscow, Russia
2 Beauty institute, Moscow, Russia
∗ Corresponding author.
Introduction The pathogenesis of dissatisfaction of the own
appearance in patients without obvious abnormalities is still
unexplored. The aim of the study was to investigate the struc-
ture of psychopathological disorders in patients without evident
appearance abnormalities seeking for surgical or cosmetological
correction.
Methods Study sample has included 227 women (average
age: 35.8 ± 4.9 years) and 54 men (average age: 30.9 ±5.7
years)–patients of plastic surgery and cosmetology clinic. The study
used clinical psychopathological and follow-up methods of exami-
nation.
Results We have found the heterogeneous spectrum of mental
disorders in this group of patients: overvalued dysmorpho-
phobia was diagnosed in 26%, anxiety-phobic disorders–23.1%,
obsessive-compulsive disorders–in 11%, depression–in 32%, delu-
sional disorders–in 7.5% of patients.
Conclusions The results of our study show that the phenomenon
of dissatisfaction with the appearance without obvious cosmetic
defects manifests in the course of wide spectrum of mental disor-
ders. The follow-up shows no improvement and even worsening of
patients’ mental state after cosmetological or surgical treatment.
Decision about possibility and extent of the operation should be
based on the analysis of patient’s mental state and motive for refe-
rence to aesthetic medicine specialist.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0615
The development of an abbreviated
version of the Cornell scale for
depression in dementia (CSDD) for the
assessment of depression in palliative
care inpatients
M. Mohamad ∗ avis womey Lucey Conroy
D. Adamis Meagher
1 University of Limerick, psychiatry, Limerick, Ireland
2 Milford care centre, palliative medicine, Limerick, Ireland
3 Sligo mental health services, psychiatry, Sligo, Ireland
∗ Corresponding author.
Introduction In the palliative care setting, accurate identification
of depression is important to allow delivery of appropriate treat-
ments.
Aims: – 1. To assess rates of depression in palliative care inpa-
tients using the CSDD, comparing with formal clinical diagnosis
based on diagnostic and statistical manual of mental disorders
(DSM-IV) criteria;
– 2. To identify items of the CSDD that most distinguish depressive
illness in a palliative care setting.
Methods We measured rates of depression in patients admitted
into a palliative care inpatient unit with the CSDD. DSM-IV clinical
diagnosis of major depressive disorder (MDD) was achieved using
all available clinical information by an experienced independent
rater. We calculated Cohen’s Kappa to measure concordance bet-
ween the CSDD and DSM-IV diagnosis.
Results We assessed 142 patients (56.3% male; mean age: 69.6
years), the majority of which had a cancer diagnosis (93.7%). 18.3%
(n = 26) met DSM-IV criteria for MDD, while 12% scored ≥6 on the
CSDD with 15 cases of depression common to these two methods
(K= 0.65). Discriminant analysis identified five CSDD items that
were especially distinguishing of MDD; sadness, loss of interest,
pessimism, lack of reactivity to pleasant events and appetite loss.
An abbreviated version of the CSDD, based on these 5 items, pro-
ved highly accurate in identifying DSM-IV MDD (AUC = 0.94), with
sensitivity of 89% and specificity of 84% at a cut-off score ≥2.
Conclusions There was good level of concordance between the
CSDD and DSM-IV diagnosis of MDD. We identified five depres-
sive symptoms that are especially discriminating for depression in
palliative care patients.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0616
Second generation direct-acting
antiviral (DAAs) Treatment on HCV+
patients: Patient reported outcomes
(PROs) and psychiatric symptoms in a
real world setting sample
M. Moneglia ∗ antangelo urian ragnani
F. Elisa Quargnolo allanti . Zignego
1 Azienda Ospedaliero-Universitaria Careggi, Neurofarba, Florence,
Italy
2 Azienda Ospedaliero-Universitaria Careggi, Masve, Florence, Italy
∗ Corresponding author.
Introduction Anti-HCV treatments are moving away from
interferon-alpha towards DAAs, associated with fewer side effects,
better tolerability, and better PROs.
Aims To describe neuropsychiatric symptoms and PROs during
DAAs treatment in a group of HCV+ patients.
Methods Forty outpatients, scheduled for DAAs treatment, were
assessed at enrolment (T0), 4 weeks (T1), at the end of treatment
(EOT) and after 12 weeks of follow up (F-UP), by means of MDRS,
HAM-D, HAM-A, MRS, Y-BOCS and SF-36. Afterwards the sample
was divided into two groups as a function of a positive psychiatric
history (19) and compared with each other.
Results Total sample mean scores between W0 and F-UP were
compared and an improving trend was observed in all administe-
red scales. An SF-36 items analysis showed a statistically significant
difference in emotional role functioning between W0 vs EOT and
EOT vs F-UP, in change in overall health status between W0 vs
EOT andW0 vs F-UP.Amultivariate logistic regression analysis sho-
wed that a positive psychiatric history was not associated with an
improvement in vitality of 4.3 (minimal clinically important dif-
ference). Comparing the two groups, no significant fluctuations in
SF-36 scores were founded and major deviations score increases
were recorded in patients with a psychiatric history in all scales.
Conclusions Our real world data shows that new regimens do not
seem to be associated with psychiatric side effects and conversely a
clinical improvement compared to baseline was found, suggesting