European Psychiatry - Volume 41 - April 2017

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S484 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S465–S520
been provided only for a pediatric comorbidity. High rates of co-
occurrence may be mediated by the existence of tic disorders,
and evidence of impaired neuronal maturational processes in OCD
pediatric population may lead to probably transitory phenotypi-
cal expressions that look like ADHD symptomatology. Thus, it is
possible that ADHD-like symptoms resulting from OCD-specific
symptomatology may be misdiagnosed as ADHD. This may explain
the lower co-occurrence rates reported in adolescents and adults.
Conclusion OCD and ADHD are very different disorders in terms
of pathophysiology, phenomenology, and treatment strategies.
Several methodological concerns have been identified in our
review. Future studies on OCD-ADHD comorbidity should try to
mitigate these biases.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0244
Other ways for the treatment of
alcohol dependence: A patient treated
with nalmefene
O. Porta Olivares ∗, M. Juncal Ruiz , M. Gómez Revuelta ,
G. Pardo de Santayana Jenaro , L. Sánchez Blanco ,
R. Landera Rodriguez , A.B. Pérez Santos ,
F. Arnaiz de Las Revillas Almajano
1 Hospital universitario Marqués de Valdecilla, general psychiatry,
Santander, Spain
2 Hospital universitario de Álava, general psychiatry, Vitoria-Gasteiz,
Spain
3 Hospital universitario Marqués de Valdecilla, general medicine,
Santander, Spain
∗ Corresponding author.
Introduction Alcohol dependence belongs to one of themajor risk
factors to health worldwide. Alcohol consumption is a significant
factor for mortality in the world: 6.3% in men and 1.1% in women.
The alcohol use disorder is also very common: 5.4% in men, 1.5%
in women. Despite its high frequency and severity of this disorder,
only 8% of all alcohol dependents are treated once.
Aims An interesting treatment option is geared toward reducing
alcohol intake. Some patients in treatment for alcohol use disor-
der prefer an initial target of reducing consumption. Nalmefene,
an antagonist naltrexone associated with opioid receptors, has
been authorized in the European Union to help alcohol-dependent
patients reduce their consumption. Antagonists’ opiate receptors
are associatedwith reduced reward in relation to alcohol consump-
tion, thus helping patients in reducing energy consumption.
Methods A man of 39 years old, with a diagnosis of alcohol use
disorder and depressive disorder and poor outcome despite dif-
ferent types of treatment (as aversive agents) was treated with
nalmefene.
Results After a few months, nalmefene had a beneficial effect on
the patient, with a significant reduction in the number of days of
excessive alcohol consumption and total consumption in the sixth
month. In addition, treatment was well tolerated, with no observed
secondary effects.
Conclusions Nalmefene appears to be effective and safe in reduc-
ing heavy drinking. Drugs such as nalmefene have demonstrated
efficacy in association with a biopsychosocial approach to help
patients achieve their personal objectives for this disorder.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0245
Rehabilitation program: Results of
a clinic in Lisbon
H. Prata-Ribeiro ∗, S. Hanneman , C. Ana
1 Centro hospitalar Psiquiátrico de Lisboa, servic¸ o de psiquiatria geral
e transcultural, Coimbra, Portugal
2 Centro hospitalar psiquiátrico de Lisboa, Servic¸ o de reabilitac¸ ão,
Lisboa, Portugal
∗ Corresponding author.
Introduction Modern psychiatry includes within its purposes to
reintegrate patients into society. Our work’s goal is to evaluate in
terms of outcome, the current status of patients that underwent the
rehabilitation program in a clinic in Centro Hospitalar Psiquiátrio
de lisboa, in Lisbon.
Methods The methods consisted of retrospective evaluation of
the sample of patients that successfully completed the rehabilita-
tion program between 2012 and 2015. Gender, age, provenience,
previous and current socio-economic situations were taken into
account.
Discussion Twelve patients concluded the program in the time-
frame studied: 64 % males and 36 % between the ages of 36 and
40 and more than half were in homelessness situations. They pro-
gressed in increasing levels of autonomy and by the program’s end,
ten were dismissed and two were still waiting for housing. Ten of
the patients are now living with their families or have been inte-
grated in social housing program. Two await conditions to leave the
hospital.
Conclusion The program had a positive impact on the life of all
patients that have engaged in it. Only two remain waiting social
housing responses. Although the results are satisfactory, the num-
ber of patients admitted must improve in coming years.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0246
From alcohol to delusional jealousy
M. Rodríguez ∗ ojas rtega oretti
1 Centre hospitalier Torrecárdenas, psychiatry, Almería, Spain
2 H. De Poniente, psychiatry, Almería, Spain
∗ Corresponding author.
Purpose With this clinical case we want to show an example of
diagnosis and treatment of a frequent psychiatric comorbidity in
alcohol dependence: delusional jealousy.
Methods We analyzed a clinical case of a 52-year-old man who
has a voluntary drug intake promoted by a delusional jealousy to his
wife in a context of chronic alcohol consumption. A bibliographic
search is made about the comorbidity of delusional jealousy in
alcoholism.
Results A 52 year-old man is brought to the hospital after to have
a voluntary drug intake. He has not got medical history of mental
health. As personal antecedents, the harmful alcohol consump-
tion of the last 6 years in which he is unemployed is highlighted.
After the clinical interview with the patient and with direct rela-
tives (woman and daughter), we have the suspicion that it is a
case of cellotipia induced by alcohol, in which the patient has
made an autolytic attempt fomented by a delusion of jealousy.
In this moment treatment is started. After a few weeks in which
the patient starts treatment and leaves alcohol consumption, delu-
sional clinic of jealousy refers progressively.
Conclusions The alcoholic etiology of cellotipia has not been
specifically confirmed. However, clinical experience shows this
association is extremely frequent. It’s a chronic delusional disorder
with content of jealousy, providing interpretations and suspicions
unfounded. Is added hostility to his partner, with potential risk
of heteroagresivity. The most important thing is to assess the