European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S465–S520 S503
was seen in 38% of the patients. The most common condition was
IDD (27.1%), followed by affective and anxiety disorders (22 and
15.3% respectively). Considering patients with IDD, we found dif-
ferences in locus (P = 0.001) (present in 34.3% of non-stablished
locus, 8.6% of extra-temporal locus and 57.1% of temporal locus)
but not with hemisphere, sex, type of crises, treatment. We nei-
ther found correlation with age, number of crisis or number of
treatments.
Conclusions Psychiatric co-morbidities as IDD do not appear in
the DSM-IV but are prevalent and could be related with temporal
locus.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0305
Cardiovascular risk factors, anxiety
symptoms and inflammation
markers: Evidence of association from
a cross-sectional study
G. Rioli ∗, S. Tassi , G. Mattei , S. Alboni , S. Mancini ,
C. Artoni , M. Galletti , N. Giambalvo , G. Galli , M. Marchi ,
A. Minarini , G. Montardi , D. Perrone , G. Pollutri ,
L. Roncucci , S. Saraceni , G. Spiga , C. Visentini ,
G.M. Galeazzi , S. Ferrari
1 Università degli Studi di Modena e Reggio Emilia, Scuola di
Specializzazione in Psichiatria, Modena, Italy
2 Università degli Studi di Modena e Reggio Emilia, Corso di Laurea in
Medicina e Chirurgia, Modena, Italy
3 Università degli Studi di Modena e Reggio Emilia, Dipartimento di
Scienze della Vita, Modena, Italy
4 Università degli Studi di Modena e Reggio Emilia, Dipartimento di
Medicina Diagnostica- Clinica e di Sanità Pubblica, Modena, Italy
5 Università degli Studi di Modena e Reggio Emilia, Dipartimento di
Medicina Diagnostica- Clinica e di Sanità Pubblica- sezione di
Psichiatria, Modena, Italy
∗ Corresponding author.
Introduction Anxiety disorders and Cardiovascular (CV) diseases,
among the most common disorders in Western World, are often
comorbid. A chronic systemic inflammatory statemight be a shared
underlining pathophysiological mechanism.
Aims To investigate the association between anxiety symptoms,
CV risks factors and inflammatorymarkers in an outpatient sample.
Methods Cross-sectional study. Inclusion criteria: outpatients
aged ≥ 40 years, attending colonoscopy after positive faecal occult
blood test, negative medical history for cancer. Collected data:
blood pressure, glycaemia, lipid profile, waist circumference,
BMI, PCR (C Reactive Protein), LPS (bacterial Lipopolysaccharide).
Psychometric tests: HADS, TCI, IMSA, SF36. Statistical analysis per-
formed with STATA13.
Results Fifty four patients enrolled (27 males, 27 females).
Sixteen patients (30.19%) were positive for anxiety symptoms.
Thirty-three patients (61.11%) had hypertension, 14 (25.93%)
hyperglycaemia and 64.81% were overweight, with frank obesity
(BMI≥ 30) in 11 subjects (20.37%). Anxiety symptoms were asso-
ciated with low hematic HDL values (OR = 0.01; P = 0.01) and high
concentration of triglycerides (OR = 0.023; P = 0.02) at the multiple
regression model. At the univariate logistic analysis, anxiety was
associated with LPS (OR = 1.06; P = 0.04).
Conclusions Further evidence over the epidemiological link
between common mental disorders and CV diseases was col-
lected, with possible hints on pathophysiology and causative
mechanisms related to inflammation. The importance of screening
for anxiety and depression in medical populations is confirmed.
Suggestions on future availability of screening tools based on
inflammatory-related indicators should be the focus of future
research.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0306
How are personality traits and
physical activity involved in colorectal
carcinogenesis? A cross-sectional
study on patients undergoing
colonoscopy
M. Marchi , S. Alboni , C. Artoni , M. Galletti , N. Giambalvo ,
S. Mancini , F. Mariani , G. Mattei , A. Merighi , G. Montardi ,
G. Pollutri , G. Rioli ∗, S. Saraceni , G. Spiga , C. Visentini ,
S. Ferrari
1 Università degli Studi di Modena e Reggio Emilia, Corso di Laurea in
Medicina e Chirurgia, Modena, Italy
2 Università degli Studi di Modena e Reggio Emilia, Dipartimento di
Scienze della Vita, Modena, Italy
3 Università degli Studi di Modena e Reggio Emilia, Scuola di
Specializzazione in Psichiatria, Modena, Italy
4 Università degli Studi di Modena e Reggio Emilia, Dipartimento di
Medicina Diagnostica- Clinica e di Sanità Pubblica, Modena, Italy
5 Università degli Studi di Modena e Reggio Emilia, Dipartimento di
Medicina Diagnostica- Clinica e di Sanità Pubblica, sezione di
Psichiatria, Modena, Italy
∗ Corresponding author.
Introduction Inflammatory state of the large bowel is a key factor
for the development of colorectal cancer (CRC). It has multifactorial
aetiology, including psychological determinants. Physical activity
may have a protective function against CRC via anti-inflammatory
properties; on the contrary, personality traits correlate with an
unhealthy and dangerous lifestyle.
Objective To measure the association between personality traits,
lifestyle and colonoscopy outcome.
Methods Cross sectional study. Patients undergoing colonoscopy
aged 40 or more, with a negative history for cancer or inflam-
matory bowel disease, were enrolled. Data collected: colonoscopy
outcome, smoke, alcohol, physical activity, presence/absence of
Metabolic Syndrome, personality traits assessed by the Temper-
ament & Character Inventory (TCI).
Results In a sample of 53 subjects (females = 24, 45.3%), the
mean age was 60.66± 9.08. At least one adenoma was found
to 23 patients (43.3%). Twenty patients were smokers (37.74%),
36 (67.92%) drank alcohol at least weekly; approximately 60%
reported regular physical activity. At the multivariate regression,
the outcomewas associated to: TCI Self Transcendence domain (ST)
(OR = 1.36, P = 0.04) and physical activity (OR = 0.14, P = 0.03).
Conclusion People with ST’s characteristic personality traits and
sedentary life style are more likely to have precancerous colorectal
lesions. This confirms the protective role of physical activity, and
suggests to further explore the role of personality in cancerogene-
sis.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0307
Psychiatry intervention in cerebellar
cognitive affective disorder: Case
report
O.E. Rodriguez
Gold Coast Hospital, Mental health, Broadbeach, Australia
Background/objectives Cerebellar cognitive affective syndrome
(CCAS) is a condition that arises from cerebellar lesions. CCAS can
easily be overlooked by medical teams; therefore a bibliographic