European Psychiatry - Volume 41 - April 2017

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S836 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S772–S846
use 17 to 22 (P < 0.001) with maximal difference between groups
at age 20.
Conclusions Later onset of use is associated with reduced
cannabis experiences till the early 1920s. This may have public
health implications.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1315
Restraint or not restraint. Involuntary
transport from home of schizophrenic
patients
B. Samso ∗, S. Ramos , A. Malagón , A. Gonzalez , M. Bellsolà ,
J. León , M. Llobet , L. Alba , V. Pérez , L.M. Martín ,
D. Córcoles
1 Parc de Salut Mar, Psychiatry, Barcelona, Spain
2 Hospital Can Misses, Psychiatry, Ibiza, Spain
3 Centro de investigación Biomédica en Red de Salut Mental
CIBERSAM, psychiatry, Barcelona, Spain
∗ Corresponding author.
Introduction Although physical restraint (PR) is a non-rarely
practice on psychiatry there are few studies that focus the attention
on the risk factors for this intervention. PR is a legitimacy practice
when is needed and well applied but is not free from side effects.
Knowing risk factors might be useful to improve the application of
PR.
Objectives Study the risk factors involved with the use of PR at
patient’s home in individuals with schizophrenia before the invol-
untary transport (IT) to a psychiatric facility.
Methods Is a descriptive and observational study of 267 psy-
chotic patients that were assisted by a psychiatric home care unit
(EMSE) in Barcelona during their IT. The sample was divided in
two groups, depending on the need of PR. Socio-demographic data
were collected as well as positive and negative syndrome scale
(PANSS), WHO disability assessment schedule (WHO/DAS), global
assessment of functioning scale (GAF), Scale to assess unaware-
ness of mental disorder (SUMD). Aggressiveness was assessed by
PANSS-EC consisting of 5 items: excitement, tension, hostility,
uncooperativeness and poor impulse.
Results From the 267 psychotic patients 109 required PR. 154
were male and the average of age was 47. The results were signifi-
cant in the PR group versus no PR for PANSS-EC (P= 0.000), as well
as WHO/DAS (P = 0.017), GAF (P= 0.042), Positive PANSS (P = 0.000),
age (P = 0.001) and substance use (P= 0.012). Were no significant for
gender, insight or Negative PANSS.
Conclusions Aggressiveness and violence were the most impor-
tant PR related factors followed by positive symptoms, age,
substance use and global functioning.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1316
Effectiveness in controlling symptoms
with long-acting injectable
aripiprazole
L. Sánchez Blanco ∗ Juncal Ruíz
G. Pardo de Santayana Jenaro , R. Landera Rodríguez ,
M. Gómez Revuelta , O. Porta Olivares , M. Pérez Herrera ,
N.I. Nu˜nez Moral
1 Hospital Universitario Marqués de Valdecilla, Psychiatry,
Santander, Spain
2 Hospital Universitario de Álava-Sede Santiago, Psychiatry,
Vitoria-Gasteiz, Spain
∗ Corresponding author.
Introduction Depot antipsychotic treatment has been a rad-
ical change in the evolution and prognosis of patients with
schizophrenia. Long-acting injectable aripiprazole is an anti-
psychotic dopamine partial agonist. It has a good tolerance in terms
of metabolism and prolactine level.
Objetives Studying the causes of readmission at the acute unit
of Marqués de Valdecilla university hospital (HUMV) in patients
treated with Long-acting injectable aripiprazole LAI 400mg.
Methodology This is a descriptive study which pretends to assess
the causes of readmission in a sample of 30 patients (12 women,
18 men) with non-affective psychosis, which had entered the acute
unit of HUMV from 1st January to 30th September 2016 because of
psychotic decompensations and had been treated with long-acting
injectable aripiprazole 400mg.
Results Out of the 30 patients there were five readmissions
during the observation time. Two of them for psychotic decom-
pensation, two because of premature abandonments, with oral
aripiprazole supplementation and the last one because of desertion
of injectable drug. No gender differences were observed.
Conclusions It is necessary 15 days of oral supplementation
before and after the first dose of long-acting injectable aripipra-
zole to ensure that adequate therapeutic levels are achieved and
to avoid readmissions by misuse of the drug. One of the limita-
tions encountered in this work would be the small sample size and
limited observation time. A longer-term research may allow to find
more scientific evidence to clarify the clinical safety and efficacy of
long-acting injectable aripiprazole in patients with non-affective
psychosis.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1317
Psychotic disorder of organic etiology,
in the context of sarcoidosis. A case
report
L. Sánchez Blanco ∗ Juncal Ruíz
G. Pardo de Santayana Jenaro Gómez Revuelta
R. Landera Rodríguez , O. Porta Olivares , E. López García ,
M. Pérez Herrera , N.I. Nú˜nez Morales
1 Hospital Universitario Marqués de Valdecilla, Psychiatry,
Santander, Spain
2 Hospital Universitario de Álava-sede Santiago, Psychiatry,
Vitoria-Gasteiz, Spain
∗ Corresponding author.
Introduction Neurosarcoidosis is an uncommon cause of psy-
chosis. It courseswith an affectation of the brain, the spinal cord and
other areas of the nervous system. It associates both neurological
and psychiatric symptoms: cranial mononeuropathy, myelopathy
or radiculopathy meningitis, neuroendocrine dysfunction, demen-
tia, delusions, hallucinations.
Objectives To review in Pub-Med about neuropychiatricmanifes-
tarions of neurosarcoidosis.
Methods We describe the case of 60-year-old woman diag-
nosed with long evolution schizoaffective disorder with a
recent decompensation in the context of a stressful situa-
tion. As somatic background to highlight: cognitive impairment
(encephalic bilateral and symmetrical frontal atrophy in cranial
magnetic resonance) and a probable sarcoidosis with hilia and
mediastinal lymph nodes without histologic confirmation. She was
hospitalized at the acute care unit because of a descompensation
of her schizoaffective disorder. The patient was distressed, with
delirious speech, sensoperceptive hallucinations, hypothymia and
weigth loss.
Results Firstly we evaluate the lack of clinical improvement with
an anti-psychotic drug in previous hospitalizations. For that reason,
we thought in organic mental disorder as an alternative diagno-