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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S772–S846

S843

Results

The frequency of psychotraumas, social stress and physi-

cal abuse in our group was significantly higher in women (63.33%),

in patients with urban residence (80.00%) and age group 36–45

years (46.67). There was a pattern of residual defectuality reflected

by positive symptoms (83.33%), alcohol abuse (80.00%), aggres-

sive behavior (66.67%) and suicide attempts (30.00%). The poor

course with minimal social functioning (GAFS < 40; 36.67%) was

correlated with a high number of relapses and hospitalizations (> 9

hospitalizations; 43.33%), cognitive deficit (MMSE < 23; 76.67%).

The psychosocial factors involved in the pathogenesis and course of

schizophrenia were social stress (60.00%), physical abuse in child-

hood and adolescence (20.00%) and psychotraumas (20.00%).

Conclusions.

Psychotrauma and physical abuse in childhood and

adolescence and during the course of paranoid schizophrenia con-

stitute a risk factor for a poor outcome with cognitive deterioration,

aggressive and suicidal behavior that call for prophylactic meas-

ures and qualified psycho-social interventions associated to the

pharmacological treatments.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.01.1664

EV1335

Differential diagnosis and therapy of

cycloid psychoses: A case report

A.M. Uminska-Albert

, G. Eikmeier

Klinikum Bremerhaven, Klinik für Psychiatrie- Psychotherapie und

Psychosomatik, Bremerhaven, Germany

Corresponding author.

Kraepelin already challenged his dichotomy of psychoses, because

in clinical practice too many cases were not in line with his pattern.

Different terms for these disorders were coined. Leonhard sepa-

rated cycloid psychoses fromother forms of endogenous psychoses.

The idealized subtypes (anxiety-beatific, hyperkinetic-akinetic-

motility and confusional exited-inhibited) are characterized by a

bipolar course with complete recovery. Operationalised criteria

were developed by Perris. We report on a 60 year old woman

diagnosed as schizophrenic in 1984/1985 and 2006. In August

2015 she was admitted with stupor and mutism and therefore

was treated with fluphenazine and lorazepame. Six days later the

clinical picture changed, she became confused and very agitated.

After change of treatment to benperidole her clinical condition

improved within 12 days. After 3 further days she became con-

fused, agitated and euphoric again. The symptoms persisted in spite

of a change of treatment to haloperidole. After diagnostic revi-

sion therapy was augmented with lithiumcarbonate. Six days later

the psychotic symptoms began to improve and were completely

remitted after 10 further days. The case report points out that a

differential-diagnostic revision of an apparently therapy-resistant

schizophrenia should not only be carried out according to ICD 10

criteria but a cycloid psychosis should be taken into account, too.

Perris-criteria are contrastedwith ICD 10-criteria for schizophrenia

andmania with psychotic symptoms. Symptomatology and clinical

course in our patient fulfilled exactly the Perris-criteria. We recom-

mend an augmentation trial with lithium in acute phases of cycloid

psychoses by all means before ECT.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.01.1665

EV1336

Attitude of person living with

psychosis towards MH professionals:

A qualitative study

K. Vaiphei

1 ,

, P. Sreedaran

2

, V. Sathyanarayanan

2

1

St. John’s Medical College Hospital, Psychiatry, Bangalore, India

2

St. Johns Medical College Hospital, Psychiatry, Bengaluru, India

Corresponding author.

Aims

Studies investigating attitudes of people with mental ill-

ness are scarce. The aim of the present study was to investigate

person living with psychosis on their attitudes and perception

towards the mental health professionals in contact with mental

health services.

Methods

An in-depth interview was used to explore their lived

experiences and attitude towards mental health professionals.

Results

Both negative and positive attitudes were prevalent

among the patients. Most negative attitudes concerned on not giv-

ing time, the MHPs are most interested in financial gains. They

felt attitude changes according to diagnosis, psychosis perceived

as diagnosis with violence; they are more interested in protecting

themselves, perception that treating symptoms and not cause of

illness. On the contrary, they felt positive on the relationship and

time given to them.

Discussion and conclusions The PLWI’s attitude to MHPs could be a

product of the type of admission (forced upon), symptoms related

or on the type of service settings. The present study is purely qual-

itative, single settings, could not be generalised. However it points

on the need for sensitization of MHPs and relationship building

oriented intervention.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.01.1666

EV1337

Parkinson’s disease and psychosis:

Report of a case

M. Valverde Barea

1 ,

, A. Espa˜na Osuna

1

, F. Cartas Moreno

2

1

Complejo Hospitalario de Jaén, Psiquiatria, Jaen, Spain

2

USMC-Úbeda, Psiquiatria, Jaen, Spain

Corresponding author.

Introduction

Jealous delusional ideation appears in 7-14% of

cases of Parkinson’s disease. Treatment with dopaminomimet-

ics drugs is a significant risk factor for psychosis. However, the

most likely etiology of psychosis in these patients is a loss of

central cholinergic function associated with age since described

psychosis even before the introduction of the L-Dopamine. Cogni-

tive impairment and sleep disorders are predictors of development

of psychosis.

Objective

Present a clinical case of psychosis in Parkinson’s dis-

ease and its treatment.

Method

Reason for consultation. Patient diagnosed with Parkin-

son’s disease with behavioral disorder and delusional.

Current illness

The patient after antiparkinsonian medication

has increased suspicion, self-referentiality, delusional jealousy

ideation to her husband, delusional interpretations regarding

somatic symptoms, insomnia and behavioral disorders with

aggression.

Family background

Mother with Alzheimer’s.

Personal history

No contact with mental health.

Psychopathological examination

Conscious, repetitive language,

dysphoric mood with delusions of prejudice and jealousy.

Mixed insomnia.

Diagnosis

Psychosis in Parkinson’s disease.

Treatment

Quetiapine 300mg/day. Carbidopa 25mg/L-dopa

100mg: 1-0-1. On subsequent visits quetiapine was suspended and

replaced by clozapine 200mg/day.

Results

The treatment of psychosis was effective with the use of

quetiapine and subsequently clozapine with good tolerance and

effectiveness. He also said lower antiparkinsonian medication.

Conclusions

Psychotic symptoms are the most common psychi-

atric clinic in Parkinson’s disease. Often not enough antiparkinso-

nian dopaminomimetics reduced to control psychotic symptoms

and use of antipsychotics is required. The use of antipsychotics in