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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S170–S237


A decreased ability to identify emotions is directly

correlated with decreased social functioning in subjects with

schizophrenia spectrum disorders.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.


Long acting antipsychotics treatment

of schizophrenia: A 24-month

prospective study on patient’s attitude

towards treatment

E. Calderani

, F. Pietrini , I. Burian , F. Chiarello , D. Dahlke ,

S. Gemignani , P. Marino , G.A. Talamba , L. Poli , A. Santangelo ,

V. Ricca , A. Ballerini

University of Florence, Neuro. Far. Ba, University of Florence,

Florence, Italy

Corresponding author.


Long-acting injectable (LAI) second-generation

antipsychotics (SGAs) are considered an alternative to oral antipsy-

chotics for schizophrenic patients with low adherence to therapy.

However, it is still a matter of debate whether LAI-SGAs are able to

significantly improve patient’s attitudes towards treatment (ATT)

[1] .


To investigate the impact of LAI on ATT over 24months.


Nineteen schizophrenic patients were switched from

either oral olanzapine (11) or paliperidone (8) to the corresponding

LAI. Patients were assessed at baseline (T0), after 6 (T1), 12 (T2) and

24 months (T3). Drug Attitude Inventory-10 (DAI-10)

[2] w

as used

to assess ATT. Young Mania Rating Scale (YMRS), Montgomery-

Asberg Depression Rating Scale (MADRS), Positive and Negative

Syndrome Scale (PANSS), and Short Form Health Survey (SF-36)

were used for psychopathology evaluations.


Eleven patients reached T3. Eight patients were excluded

(4 olanzapine, 4 paliperidone): 4 required a significant change in

concomitant treatment, 4 a change of antipsychotic (metabolic

comorbidity). No changes in psychopathology occurred between

T2 and T3, some scales improved from baseline to T2. DAI-10 mean

scores were improved after 12 months, thus not significantly, and

were further improved at 24 months (


= .008 vs baseline).


ATT keeps improving after one year of LAI treatment,

unrelated to clinical response.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.


[1] Kaplan G, Casoy J, Zummo J. Impact of long-acting injectable

antipsychotics onmedication adherence and clinical, functional,

and economic outcomes of schizophrenia. Patient Prefer Adher-

ence 2013;7:1171–80.

[2] Nielsen RE, Lindström E, Nielsen J, Levander S. DAI-10 is as

good as DAI-30 in schizophrenia. Eur Neuropsychopharmacol



Relationship between cognition and

primary negative symptoms

sub-domains in schizophrenia

O.O. Capatina

1 ,

, I.V. miclutia


, A. toma



University of Medicine and Pharmacy Iuliu Hatieganu, Psychiatry,

Cluj-Napoca, Romania


Psychiatry City Hospital Tarnaveni, Psychiatry, Tarnaveni, Romania

Corresponding author.


The relationship between negative symptoms and

cognition in schizophrenia is not clear, a number of authors whom

studied this relationship came up with inconsistent findings and

meta-analyses show that there is a small moderate associations

between the two domains.

Objectives and aims

The aim of this study was to investigate the

relationship between cognition and the primary negative symp-

toms sub-domains.


Sixty-seven female patients with schizophrenia were

evaluated using PANSS ans NSA-16 scales. Correlation and regres-

sion analyses were used in the present study to investigate

the relationship between the primary negative symptoms sub-

domains obtained by using the principal component analysis, and

cognition evaluated with the PANSS using the 5 factor model as

described by Lindenmayer.


No relationship was found between the PANSS Cognitive

factor and Negative factor, but when investigating the relation-

ship of the Cognitive PANSS factor with the negative sub-domains:

diminished expression (DE) and avolition-apathy (AA), it was

shown that there is a significant association between cognition

and AA domain, but there was shown no association with the DE

domain, and there was just a small association with the composit

score of the NAS-16.


Our study reveals the relative independence of cog-

nitive factor from the negative domain of the psychopathology,

even though the association with AA domain was clear. These find-

ings also support the need of using appropriate assessment tools

in order to get a refined understanding of the phenomenology of


Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.


Assessing suicide risk with the Clinical

Interview for Psychotic Disorders

(CIPD): Preliminary reliability and

validity of the Suicide Risk Scale for

Psychosis (SRS-P)

M.J. Martins

1 , P. C


1 , C. C


2 , T. P


3 ,

J. Gonc¸ alves


, R. Guiomar


, C. Marques


, A. Pinto



D. Carreiras

1 ,

, M. Bajouco


, A. Macedo



Faculty of Psychology and Educational Sciences, University of

Coimbra, CINEICC, Coimbra, Portugal


University of Azores, Portugal, Department of Educational Sciences,

Ac¸ ores, Portugal


Faculty of Medicine, University of Coimbra, Psychological Medicine

Department, Coimbra, Portugal

Corresponding author.


Suicide risk is an important variable to consider both

in assessment and throughout the therapeutic process in psychotic

disorders. The SRS-P is an 18-item scale computed from the patient

and clinician-rated scores obtained in the CIPD. The scale comprises

lifetime assessment of depressed mood, anhedonia and its current

interference and severity, current and past feelings of hopeless-

ness, suicidal ideation, ‘voices’ about suicide, and suicide-related



To assess reliability and convergent validity of the SRS-P in

a sample of participants with psychosis.


The sample comprised 22 participants (68.2% male),

single (72.7%), between 19 and 47 years old (M= 31.05; SD = 7.088),

with 4–17 years of education (M= 11.77; SD = 3.176), employed

(50%). The most prevalent diagnosis was schizophrenia (68.2%) and

the participants had a mean of 1.90 hospitalizations (SD = 2.548).

The mean age of illness onset was 23.57 years (SD = 5.555). The

participants were assessed with the CIPD, Depression, Anxiety and

Stress Scales-21, Forms of Self-Criticism and Reassurance Scale,

Self-Compassion Scale, Other as Shamer Scale and the Empower-

ment with Psychotic Symptoms Scales.