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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S170–S237


The aim of this study was to determine the levels

of depression, anxiety and attention-deficit hyperactivity disorder

symptoms and health-related quality of life (HRQL) in children and

adolescents with epilepsy.


The sample consisted of 75 children with epilepsy and

50 healthy controls aged 8–18 years. Questionnaires were used to

evaluate the psychiatric status and HRQL of the patients.


Patients had lower child-rated psychosocial and total

area HRQL scores, and lower parent-rated psychosocial, physi-

cal and total area HRQL scores than the controls did. Inattention

scores of the epilepsy group were significantly higher compared to

controls. No significant differences were found between patients

and controls in terms of anxiety and depression scores. Regarding

determinants of HRQL, severity of depression and anxiety had a

decreasing effect on child-rated HRQL total scores; and severity of

anxiety had a decreasing effect on parent-rated HRQL total scores.


Epilepsy is associated with poor QoL in childhood

and severity of depression and anxiety are among the determi-

nants of QoL. Clinicians should be more aware of accompanying

psychiatric symptoms in epileptic patients and take the necessary

precautions in the early period of the illness in an effort to improve


Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.


The new great

imitator – neuropsychiatric

symptoms of Lyme disease

M.C. Cochat Costa Rodrigues

1 ,

, I. Moreira


, M.J. Peixoto



C. Silveira



Magalhães Lemos Hospital, Psychiatry, Porto, Portugal


Hospital D.


Estefânia, Centro Hospitalar de Lisboa Central,

Department of Child and Adolescent Psychiatry, Lisboa, Portugal


Centro Hospitalar de São João, Clinic of Psychiatry and Mental

Health, Porto, Portugal

Corresponding author.


Lyme disease, caused by the spirochete



as recognized as a possible cause of multisystemic sig-

nals and symptoms, including symptomatology of the central as

well as the peripheral nervous system.


Identification of neuropsychiatric symptoms associ-

ated with Lyme disease.


Literature review in the light of researched articles pub-

lished in Pubmed/Medline as well as related bibliography.


Since the identification of the etiology of syphilis in the

early twentieth century, mental health professionals consider the

fact that serious psychiatric symptoms can be caused by infections

of the central nervous system and that early antibiotic treatment

can prevent permanent neurological/psychiatric damage. Syphilis

was known as “the great imitator” because its multiple mani-

festations mimic other known diseases. In recent years, a new

epidemic, also with multiple manifestations emerged–Lyme dis-

ease, also known as the “new great imitator”. Like syphilis, Lyme

disease may be associated with neuropsychiatric symptoms, which

means that often these cases are initially referred for psychi-

atric services, before another diagnosis is made. The incorrect

assessment of these patients as individuals with functional psy-

chiatric disease can result in a delay in the start of antibiotic

treatment and may cause serious neurological and psychiatric



According to the review, the authors propose that

in the evaluation of acute psychiatric disease or atypical chronic

disease, with poor therapeutic response, Lyme disease should be

considered and ruled out, especially if there is epidemiological con-

text and absence of psychiatric family antecedents.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.


Attention, vigilance and visuospatial

functioning in hospitalised elderly

medical inpatients – relationship to

delirium syndromal status and motor

subtype profile

C. Daly

University of Limerick, psychiatry, limerick, Ireland


The early and efficacious detection of neurocognitive

disorders poses a key diagnostic challenge. We examined how bed-

side cognitive tests perform across the spectrum of delirium and

motor subtypes.


The performance on a battery of bedside cognitive tests

were compared in elderly medical inpatients with DSM-IV delir-

ium, subsyndromal delirium, and no neuro cognitive disorder and

in motor subtypes.


One hundred and ninety-eight patients (mean age



8.26) were assessed with no delirium (


= 43), subsyndro-

mal delirium (


= 45), and full syndromal delirium (


= 110). The

ability to meaningfully engage with the tests varied from 59% for

vigilance B test to 85% for Spatial Span forward test and was found

to be least in the full syndromal delirium group. The no delirium

group was distinguished from the delirium groups for all the tests

and from the full syndromal delirium group for the vigilance B test

and global visuospatial function test. The subsyndromal delirium

group differed from the full syndromal delirium group in respect

of global visuospatial function test, spatial span backwards and

vigilance A tests. Patients with full syndromal delirium were best

identified using the interlocking pentagons test and clock drawing

test whereas those with subsyndromal delirium were best iden-

tified using interlocking pentagons test and months backwards

test. Those with subsyndromal delirium were significantly better

in their ability to engage than those with full syndromal delirium.


Simple bedside tests of attention, vigilance, and vis-

uospatial ability are useful to help to distinguish neurocognitive

disorders namely subsyndromal deliriumfromother presentations.

Disclosure of interest

The author haS not supplied his/her decla-

ration of competing interest.


The effects of bariatric surgery on

pharmacokinetics of antidepressants:

A systematic review

L. de Jonge

1 ,

, S. Petrykiv


, J. Fennema


, M. Arts



Leonardo Scientific Research Institute, Geriatric Psychiatry, Bergen

op Zoom, The Netherlands


University of Groningen, University Medical Center Groningen,

Department of Clinical Pharmacy and Pharmacology, Groningen, The



GGZ Friesland, Geriatric Psychiatry, Leeuwarden, The Netherlands


University of Groningen, University Medical Center Groningen,

Department of Old Age Psychiatry, Groningen, The Netherlands

Corresponding author.


Morbid obesity (BMI

35) has been associated with

mood and anxiety disorders. Regular use of antidepressants is com-

mon among patients who are candidate for bariatric surgery. The

Roux-en-Y gastric bypass (RYGB) is one of the most common tech-

niques used in bariatric surgery for reducing nutrient absorption.

This type of surgery may however result in major changes in drug