European Psychiatry - Volume 41 - April 2017

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S326 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S303–S364
2 College of medicine, Princess Nourah Bint Abd-Elrahman university,
Riyadh, KSA, psychiatry department, Alexandria, Egypt
3 Psychiatry department, Zagazig, Egypt
4 College of Medicine, Princess Nourah Bint Abd-Elrahman University,
KSA, clinical department, Riyadh, Saudi Arabia
∗ Corresponding author.
Introduction The occurrence of religious symptoms in obses-
sive compulsive disorder OCD patients ranges from 0% up to 93%.
Although, frequent and influential nature of these symptoms, the
explanations of its complexity and phenomenology are deficient in
the literature.
Objectives Determine the most frequent OC religious symptoms
among OCD patients. Assess relation between the frequent symp-
toms of religious OCD and depression.
Methods Cross-sectional study was conducted among 115
consented patients diagnosed as OCD according toDSM-IV. Patients
were recruited in one year from Psychiatric clinics, Zagazig Uni-
versity, Egypt. Psychiatric interview and psychometric assessment
using Beck Depression Inventory (BDI) and OC religious symptom
scale ere done.
Results The majority of patients (57.4%) had various religious OC
symptoms. About 44% had doubts in religion in general (e.g. exis-
tence of God) and 11.3% had Blasphemous ideas. More than one
third reported doubts about performing prayers and ablution per-
fectly; 34.8% repeatedly claimed they forgot to declare intention to
pray, 36.5% had doubts about violating their ablution and 29.6%
were skeptical about doing all ablution duties. Moreover, 23.5%
reported slowor repeated readings in prayers, 25.2% had suspicions
of breaking their fasting. A strong correlation between religious OC
symptoms and total score of OC symptoms scale was confirmed.
Most of our patients showed positive correlation between degree
of depression and total score OC symptoms scale.
Conclusions Muslim patient present with specific phenomeno-
logy of religious OC symptoms. These symptoms are very frequent
and negatively influencing their mood.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
Reference
[1] Abohendy W, Moemen D. Obsessive compulsive religious
symptom scale: Egyptian association of psychologists.
2006;16(3):469–518.
EW0643
Human neuropsin gene – new target
in depression?
P. Gałecki ∗ sionowska , M. Talarowska
Medical university of Lodz, department of adult psychiatry, Lodz,
Poland
∗ Corresponding author.
Introduction Neuropsin (NP, kallikrein 8, KLK8)–a kallikrein
gene-related (KLK) endoprotease–plays a key role in neuro-
plasticity processes. Neuropsin expression takes places both
extracellularly and inside neurons within the area of the hippocam-
pus. Various forms of electrophysiological stimulation (kindling,
LTP, stress) increase neuropsin expressionwithin the hippocampus
and in many other regions of the brain (e.g. neocortex, amyg-
dala). Neuropsin is mainly engaged in the early stage of LTP and in
the process of synaptogenesis. Social cognition deficits (difficulties
with identification, naming and analysing experienced emotional
states) in the group of people suffering from depression have been
described in scientific papers published in recent years. They are
considered the core features of major depressive disorders.
Aims The aim of this study is to link the human neuropsin gene
(hNP) expression with the ability of the examined subjects to use
nonverbal communication in social interactions.
Methods 120 individuals meeting the diagnostic criteria for a
recurrent depressive disorders (rDE) were qualified to participate
in the study. The Emotional Intelligence Scale–Faces task and two
subtests fromThe Right Hemisphere Language Battery (RHLB) were
used in the study.
Results Significant interrelations between expression on the
mRNA level for the hNP gene and the variables used to assess
social competences were confirmed. Results of the statistical analy-
sismake it possible to confirman inversely proportional correlation
between the analysed variables.
Conclusions Increased hNP expression is associatedwith a reduc-
tion of interpersonal abilities in the people affected by depression.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0644
The impact of residual symptoms on
relapse and quality of life among Thai
depressive patients
T. Tantrarungroj ∗, D. Nakawiro , T. Wongpakaran ,
N. Wongpakaran , P. Bookkamana , M. Pinyopornpanish ,
P. Lueboonthavatchai , N. Apisiridej , N. Saisavoey ,
K. Wannarit , T. Srichan , R. Ruktrakul , S. Satthapisit ,
A. Temboonkiat , N. Tubtimtong , S. Rakkhajeekul ,
B. Wongtanoi , S. Tanchakvaranont , U. Srisutasanavong ,
R. Nivataphand , D. Petchsuwan
1 Faculty of medicine, Ramathibodi hospital, department of
psychiatry, Bangkok, Thailand
2 Faculty of medicine, Chiang Mai university, department of
psychiatry, Chiang Mai, Thailand
3 Faculty of science, Chiang Mai university, department of statistics,
Chiang Mai, Thailand
4 Faculty of medicine, Chulalongkorn university, department of
psychiatry, Bangkok, Thailand
5 Trang hospital, department of psychiatry, Trang, Thailand
6 Faculty of medicine, Siriraj hospital, Mahidol university,
department of psychiatry, Bangkok, Thailand
7 Lampang hospital, department of psychiatry, Lampang, Thailand
8 Khon Kaen regional hospital, department of psychiatry, Khon Kaen,
Thailand
9 Phramongkutklao hospital, department of psychiatry and
neurology, Bangkok, Thailand
10 Faculty of medicine, Naresuan university, department of
psychiatry, Pitsanulok, Thailand
11 Srisangwal hospital, department of psychiatry, Mae Hong Son,
Thailand
12 Queen Savang Vadhana memorial hospital, department of
psychiatry, Chonburi, Thailand
∗ Corresponding author.
Introduction Residual symptoms of depressive disorder are
major predictors of relapse of depression and lower quality of life.
This study aims to investigate the prevalence of residual symptoms,
relapse rates and quality of life among Thai patientswith depressive
disorders.
Methods Hamilton Rating Scale for Depression (HAM-D) and
EQ-5D were used to measure the symptoms of depression and
quality of life, respectively. Prevalence of residual symptoms of
depression was collected. Regression analysis was administered
to predict relapse and patients’ quality of life at the 6 months
post-baseline.
Results Two hundred and twenty-four depressive disorder
patients were recruited. Most of patients (93.3%) had at least one
residual symptom, and the most common residual symptom was
anxiety symptoms (76.3%; 95% CI, 0.71 to 0.82). After 3 months
post-baseline, 114 patients (50.9%) were in remission and within 6
months, 44 of them (38.6%) relapsed. Regression analysis showed