European Psychiatry - Volume 41 - April 2017

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S36 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S8–S52
Experiences of family withdrawal, integration difficulties, and
perceived lack of care may contribute to suicide within the refugee
populations. Identifying effective treatments and support to min-
imize the risk especially once the individuals arrive in their new
country is key to providing appropriate care. Barriers to mental-
health care including lack of knowledge about available resources,
communication or language barriers, cultural beliefs about origins
and treatment of mental disease, as well as a lack of trust in author-
ity, pose a challenge for health care providers and policy makers.
Research has been inconsistent in the findings for the prevalence of
mental disorders, suicidal behaviours, and suicide ideation among
refugees and asylum seekers. Thus far, research has been limited
to small scale, non-randomised, often qualitative analysis. Several
studies have found higher rates of mental disorder, whereas oth-
ers have found a similar prevalence as in the general population,
although, Post-Traumatic Stress Disorder has more consistently
been found to have a higher prevalence amongmigrants. The lack of
early and thorough exploration of suicidal intent in this population
requires large-scale quantitative studies to evaluate the effective-
ness and feasibility of current practices in mental-health care and
suicide prevention.
Disclosure of interest The author has not supplied his declaration
of competing interest.
Symposium: Reward processes in anorexia and
bulimia nervosa: a new patogenetic model and
future perspectives for treatment of eating
disorders
S094
Functional connectivity of reward
circuits in eating disorders
A. Favaro ∗ antonastaso
1 University of Padova, general psychology, Padova, Italy
2 University of Padova, neurosciences, Padova, Italy
∗ Corresponding author.
Objective Anorexia nervosa display alterations of reward systems
and some authors hypothesize the presence of a “starvation addic-
tion”. The aim of the study is to explore the resting-state functional
connectivity of dorsal and ventral striatal nuclei.
Method 51 subjects with lifetime anorexia nervosa (AN) (35
acute and 16 recovered) and 34 healthy controls underwent high
resolution and resting-state functional magnetic resonance imag-
ing.
Results The AN group showed a reduced functional connectivity
of the putamen in comparison to healthy women and this reduc-
tion appeared to be stronger in patients with lifetime binge eating
or purging. Both acute and recovered AN groups showed larger left
accumbens area in comparison to healthy women. Moreover, the
functional connectivity of bilateral nucleus accumbens and puta-
men showed significant negative correlations with the number of
obstetric complications in the AN group.
Discussion the present study supports the hypothesis that AN
is associated with structural and functional alterations of striatal
networks and unveils a possible role of obstetric complications in
the pathogenesis of striatal dysfunction.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
S095
Emotional eating in eating disorders
and obesity: Sensorial, hormonal and
brain factors involved
F. Fernandez-Aranda ∗, T. Steward , N. Mallorqui-Bague ,
Z. Agüera , S. Jimenez-Murcia
University hospital Bellvitge-IDIBELL, psychiatry eating disorders
unit and CIBERobn, hospitalet del Llobregat, Spain
∗ Corresponding author.
Obesity (OB) and eating disorders (ED) are two complex
weight/eating conditions that share phenotypic traits, including
psychopathological variables, specific environmental risk factors
and biological vulnerabilities. Both OB and ED are associated with
maladaptive eating styles that may be relevant to their develop-
ment and maintenance. In abnormal/excessive eating behavior,
a complex interplay among physiological, sensorial, psychologi-
cal, social and genetic factors influence appetite, meal timing, and
the quantity of food intake and food preferences. Neurobiological
functioning has also been found to be altered in extreme weight
conditions, namely with regards to reward processing, emotion
regulation and decisionmaking. In this presentationwewill discuss
the relevance of such components as well their interaction using
findings from cross-sectional and longitudinal studies conducted
in extreme eating/weight conditions, when compared with healthy
controls. The development of innovative treatments considering
neurobiological factors will also be covered.
Acknowledgment Researchers supported by FIS (PI14/290) and
CIBEROBN from ISCIII. Spain.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
S096
Eating disorders and sexuality: A
complex relationship
V. Ricca ∗ Castellini elli otella . Monteleone
M. Maggi
1 Florence university school of medicine, department of
neurosciences, Firenze, Italy
2 University of Naples SUN, psychiatry, Naples, Italy
3 Florence university school of medicine, department of
experimental- clinical and biomedical sciences, Firenze, Italy
∗ Corresponding author.
Introduction The relationships between Eating Disorders (EDs)
and sexuality are complex, and of interest for researchers and cli-
nicians.
Objective To identify psychopathological and clinical factors
associated with restoration of regular menses and sexual function
in EDs patients.
Aims To evaluate the role of sexuality as a moderator of the
recovery process after an individual Cognitive Behavioural Therapy
(CBT).
Methods 39 Anorexia Nervosa (AN) and 40 Bulimia Nervosa
(BN) female patients were evaluated by means of a face-to-face
interview, self-reported questionnaires, including Eating Disorder
Examination Questionnaire and Female Sexual Function Index, and
blood sample for hormonal levels and biomarkers. The assessments
were repeated at baseline, at one year follow up, and at three years
follow up.
Results After CBT, both AN and BN patients showed a significant
improvement of sexual functioning, which was associated with
a reduction of core psychopathology. AN patients who recovered
regular menses demonstrated a better improvement across time
of psychopathological and clinical features, and were more likely
to maintain these improvements at follow up. Recovery of regu-
lar menses and improvement of sexuality at the end of CBT were