Table of Contents Table of Contents
Previous Page  41 / 916 Next Page
Show Menu
Previous Page 41 / 916 Next Page
Page Background

25th European Congress of Psychiatry / European Psychiatry 41S (2017) S8–S52


associated with a higher probability to have a full recovery at three

years follow up.


These results challenge a concept of recovery in EDs

exclusively based on weight restoration or behavioral changes. An

assessment including sexual functioning and core psychopathology

might identify the residual pathological conditions, and it is able to

provide information regarding the long term recovery process.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.


Oxytocin as a treatment enhancer in

anorexia nervosa

J. Russell

1 ,

, S. Maguire


, A. Kesby


, I. McGregor


, A. O’Dell



J. Treasure



Discipline of psychiatry university of Sydney Northside clinic,

department of psychology, Greenwich NSW, Australia


University of Sydney, department of psychology, Sydney, Australia


Discipline of psychiatry university of sydney northside clinic,

department of psychology, Sydney, Australia


Kings college London, psychological medicine- the eating disorders

research group, London, United Kingdom

Corresponding author.


Nutritional rehabilitation in anorexia nervosa (AN)

is impeded by fear of food, eating and change leading to treat-

ment resistance. Oxytocin exerts prosocial effects on anxiolysis,

fear modulation, trust and brain plasticity.


A placebo-controlled RCT examined the effects of self-

administered intranasal oxytocin (IN-OT) in AN patients.


To ascertain whether single and repeated doses of IN-OT

enhance treatment in AN.


Female AN patients self-administered twice daily 18IU



= 21) or placebo (


= 21) for 4–6 weeks during hospital

treatment. Weight and BMI were measured at baseline and after

treatment. The Eating Disorders Examination (EDE) was the pri-

mary outcome measure. Cognitive rigidity was compared between

groups after four weeks repeated dosing. The effects of the first

and last doses of IN-OT versus placebo, on salivary cortisol before

a high-energy afternoon snack, were compared.


Weight gain was similar in IN-OT and placebo groups.

Only the EDE eating concern subscale score was significantly lower

after 4–6 weeks (mean 35 days) of IN-OT (


= 0.006). Anticipatory

levels of salivary cortisol fell from baseline after the initial dose

in contrast to the placebo group where levels increased. After four

weeks IN-OT, salivary cortisol was significantly lower (


= 0.023)

overall with little anticipatory increase compared to placebo. There

were no differences in anxiety scores. Cognitive rigidity was signif-

icantly lower in the IN-OT group (


= 0.043)


Self-administered IN-OT might enhance nutritional

rehabilitation in AN by reducing eating concern and cognitive rigid-

ity. Lower salivary cortisol before a high-energy snack, suggests

reduction of fear rather than anxiety.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

Symposium: Role of psychiatry in dementia care


Pychiatrists and legal issues in

dementia care

M.M. Carrasco

Instituto de investigaciones, Psiquiátricas, Spain

During more than half a century, Psychiatry has extensively

accepted a biomedical model studying mental disorders (including

schizophrenia, affective disorders and the large group of stress-

related disorders, including anxiety disorder. Thus, the classical

dichotomy between functional and organic psychiatric disorders

is obsolete and from a theoretical point of view there should be no

obstacle for Psychiatry to deal with the study of dementias from

gene to clinical levels using empirical methods, including neuro-

transmitters and scanning techniques. However, inmany European

countries, the dementias have been claimed as belonging primar-

ily to Neurology, leaving the role of psychiatrists to treat psychotic

symptoms and bizarre behavioral disturbances.

However, psychiatrists have a long tradition of detailed psy-

chopathological description and great skill in coping with themany

psychological, ethical and social problems that are such important

features of mental disorders and particularly the dementias, and

so, the specific skills of psychiatrists will certainly be warranted in

managing the many significant psychological and social problems

of the patient both within the family and in society. The discussion

must overcome the sterile debate between specialties to focus on

the skills needed to adequately address the needs of patients with

dementia and their caregivers.

Disclosure of interest

The author has not supplied his declaration

of competing interest.


Role of psychiatrists in memory clinics

F. Verhey

University of Maastricht, The Netherlands

Memory clinics (MCs) are multidisciplinary teams involved with

early diagnosis and treatment of people with dementia. In this pre-

sentation, we will discuss several trends of the role of psychiatrists

over the last twenty years, on the basis of five questionnaires that

were sent to MCs every 5 years in the Netherlands.

MCs have developed in Europe using a range of service models

but providing similar functions, which include assessment, infor-

mation, treatment monitoring, education, training and research.

MCs may vary among each other, and across countries. Psychia-

trists used to play a coordinating role in most MCs, but there is

now a tendency that MCs are more frequently led by other special-

ists, notably neurologists. In 1998 in the Netherlands, only a small

minority of the MCs had a structural cooperation with local service

providers, but 10 years later, most of themwere collaborating with

other regional care organizations. In most cases, the collaborating

partner was a community mental health team or a long-term care


Disclosure of interest

The author has not supplied his declaration

of competing interest.