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S564

25th European Congress of Psychiatry / European Psychiatry 41S (2017) S521–S582

contains two general adult wards (42 beds), one IPCU (12 beds) and

two Elderly wards (40 beds).

Methods

Referral data was sourced across 4 consecutivemonths:

April–July 2015 (initial audit) and October 2015–January 2016 (re-

audit). These included all referrals from A&E to Psychiatry. Times

were calculated for the 4 subprocesses listed in

Table 1 b

elow.

Conclusion/discussion

Following the initial audit, interventions

such as training A&E staff to better manage psychiatric patients

and encourage earlier referrals, led to a positive response in the

re-audit (Subprocess 1). Breach rates reduced to 28% (from 35%)

on re-audit. Less breaches (81% compared to 88%) were referred

after 2-hours by A&E. Overall, the breach rates have reduced and

they are less attributable to the A&E referring patients late. The out-

come of patients leaving A&E without being seen by a psychiatrist

was unknown – adverse outcomes would strengthen the debate to

enforce the 4-hour window.

Table 1

Initial audit = 222 referrals (35% breach rate)

Re-Audit = 348 referrals (28% breach rate)

Disclosure of interest

The author has not supplied his/her decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.01.821

EV0492

Neuroleptic malignant syndrome:

Case report and literature review

R. Martín Gutierrez

1 ,

, R. Medina Blanco

1

, P. Suarez Pinilla

1

,

R. Landera Rodriguez

1

, M. Juncal Ruiz

1

,

I. Madrazo del Río Hortega

1

, M. Gómez Revuelta

1

,

O. Porta Olivares

1

, J. González Gómez

1

, J. Vázquez Bourgon

1

,

R. Hernando Fernández

2

1

Hospital Universitario Marques De Valdecilla, Psychiatry,

Santander, Spain

2

Hospital Universitario Marques De Valdecilla, General Practicioner,

Santander, Spain

Corresponding author.

Introduction

Neuroleptic malignant syndrome (NMS) is an

uncommon but potentially fatal adverse effect of neuroleptic, both

classic and atypical drugs.

Objective

To review the incidence, clinical characteristics, diag-

nosis and treatment of NMS.

Aim

We have described the case of a man of 32 years of age

diagnosed with bipolar disorder treated with lithium. He pre-

cised high-dose corticosteroids after having tonsillitis. Then, he

presented manic decompensation requiring neuroleptic treatment

(oral risperidone). After 72 hours, he presented an episode char-

acterized by muscular rigidity, fever, altered mental status and

autonomic dysfunction. Life support measures and suspension of

neuroleptic treatment were required.

Methods

A literature review of the NMS was performed using the

PubMed database.

Results

The frequency of NMS ranges from 0.02 to 2.4%. The

pathophysiology is not clearly understood but the blockade of

dopamine receptors seems to be the central mechanism. Some

of the main risk factors described are: being a young adult, the

concomitant use of lithium and metabolic causes, among others.

NMS occurs most often during the first week of treatment or after

increasing the dosage of the neuroleptic medication. Some issues of

NMS are those relatedwithdiagnosis, treatment and reintroduction

of antipsychotic treatment or not.

Conclusions

NMS canbe difficult todiagnose due to the variability

in the clinical symptoms and presentation. Because of it diagnosis

is of exclusion, clinicians should always take it into consideration

when a patient is treating with neuroleptic, especially when the

dosage has been recently increased. NMS is a clinical emergency.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.01.822

EV0493

The correlation between mood

disorders and suicide attempts for the

period 2013–2015 at “Mother Teresa”

hospital center, Fatbardha Myslimaj,

Psychiatrist, Mirela Gokaj, Deana

Rama

F. Myslimaj

, M. Gokaj , D. Rama

Mother Teresa Hospital, Psychiatry Adult, Tirana, Albania

Corresponding author.

Background

People, who have tried to commit self-injurers or

suicidal attempts, refer symptomatic presence of disorders of

humor and numerous problems social as factors precipitant to sui-

cidal thoughts and actions. It is important recognition of the signs

of suicide and self-inflicting behavior to help prevent suicide.

Materials and methods

The study includes a period of 3 years of

cases hospitalized in the psychiatric clinic UHC, since 2013–2015.

The data are taken from the records of admissions at the Psychiatric

Clinic at the University Hospital Center. Results are grouped and

studied issued by mood disorders, sex, age, place of residence and

social status.

Results

The influence of mood disorders is recently estimated

very important in causing suicide attempts compared with other

mental illnesses, similar values with contemporary literature.

Conclusions

The majority of suicide attempts do not result in

death. Many of these efforts aremade in a way that makes salvation

possible. These efforts are often a cry for help. Suicide is a social phe-

nomenon different cognitive aspect such as ethical, philosophical,

legal, psychiatric, etc. Employees of psycho-social care should be

informed about this phenomenon and finding the diagnosis, pre-

vention and treatment of suicidal attempts by persons at risk of

suicide.

Keywords

Suicide attempt; Mood disorder; Self-infliction

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.01.823

EV0494

Peculiarities of providing care in

various emergencies

S. Shport

V.P. National Research Center for Social and Forensic Psychiatry,

administration, Moscow, Russia

Air crashes

Attention is focused on providing care to the relatives

(identifying the bodies of the perished, talking to investigators, fill-

ing out the requisite documentation, etc.), resolving social issues

(organizing funerals, informing various services of what had hap-

pened, etc.).

Fires

Special attention is paid to the victims with burns at the

inpatient facilities of hospitals.

Terrorist acts

Provision of care depends on the duration of the

emergency and the number of people involved; in the case of a

continual stress, in the phase of isolation themedical-psychological

care is provided to victims’ relatives. At later stages–it is provided

to the victims and their relatives.

Natural disasters

Are of a special nature, as they are always sud-

den and there exists a threat that a great number of people may

become victims.

Organizational measures in the acute period of an emergency: