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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S53–S68

is expected that frequency of depression, neurocognitive disorders

and effective antidepressant treatment will be found to correlate

to the profile of immune biomarkers. These findings might help to

understand the etiology of depression in HIV, and specifically the

role of inflammation and immunological changes.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.


Psychosocial screening of alcohol liver

disease patients before liver


D. Telles-correia

Faculty of Medicine, University of Lisbon, Psychiatry, Lisbon, Portugal

In Europe, 30% to 50% of liver transplantations are currently due

to alcoholic liver disease (ALD). In the United States, this per-

centage is 17.2%. Post-transplant survival and other predictors

of clinical course do not differ significantly from those in other

types of transplanted patients, as long as there is no relapse of

drinking. However, 20%–25% of these patients lapse or relapse to

heavy drinking post-operatively, whichhas been associatedwith an

increased risk of liver damage and mortality. It is therefore crucial

to design specific selection and follow-up strategies aimed at this

particular type of patient. Several good and poor prognosis factors

that could help to predict a relapse have been suggested, among

them the duration of abstinence, social support, a family history

of alcoholism, abuse diagnosis versus alcohol dependence, non-

acceptance of diagnosis related to alcohol use, presence of severe

mental illness, non-adherence in a broad sense, number of years

of alcoholism, and daily quantity of alcohol consumption. In this

article, we discuss these and other, more controversial factors in

selecting ALD patients for liver transplantation. Abstinence should

be themain goal after transplantation in an ALD patient. In this arti-

cle, we review the several definitions of post-transplant relapse, its

monitoring and the psychopharmacological and psychotherapeutic


Disclosure of interest

The author has not supplied his declaration

of competing interest.

Workshop: Women in psychiatry: Mind the

gender gap


The current status of women in

psychiatry in Europe

S. Frangou

Icahn School of Medicine at Mount Sinai, Psychiatry, New York, USA

For more than two decades, psychiatry has retained its position

amongst the medical specialties with the highest proportion of

women entering residency programs. The percentage of women

in junior academic positions in psychiatry is also high and consis-

tently higher than that of men. However, the number of women

in positions of leadership remains disproportionally low at around

5% with no evidence of improvement over time. The phenomenon

of female under-representation is not unique to psychiatry or

academia. Women are under-represented in all fields of leadership

and this is a matter of wider societal concern. In this presentation,

I will discuss external and internal barriers that women face and

detail positive actions that canhelpwomen succeed in their careers.

Disclosure of interest

The author has edited and co-authored a

book on “Women in Academic Psychiatry: A mind to Succeed”


Barriers to gender equality in career

advancement and leadership

D. Wasserman

Karolinska Institute, Stockholm, Sweden

Life as a researcher includes a large amount of competition and

a heavy workload. Professor’s tasks comprise, besides their own

research, to lead your research team, to have the responsibility

for higher education, expertise in diverse contexts, review of sci-

entific articles, to seek financial support, to work with national

and international committees, to serve in administrative posts at

the university and in international associations, to write articles,

books and book chapters, to attend meetings and conferences, and

to address the many other tasks that may arise throughout one’s

career. This makes one dependent on skillful co-workers, which

should not be taken for granted. Given the constant flow of incom-

ing requests, one has to think and choose before agreeing to commit

to a task at hand, in order to not set aside your own research. This

demands a high capability to prioritize. The choice of a life partner

who can share both professional and private interests, a partner

who understands, encourages and supports, while at the same time

gives the necessary critical feedback, is a treasure. Freud said “love

and work are the cornerstones of our humanness”, but work must

be pleasurable thus try to combine work, love, and play.

Disclosure of interest

The author has not supplied his declaration

of competing interest.

Workshop: Mental health impact of SUDS on

neurodevelopmental mental disorders


Neuroimage studies: The effect of

methylphenidate in cocaine users

with ADHD

C. Crunelle

Overijse, Belgium


Attention deficit/hyperactivity disorder (ADHD) is

an important contributing factor in the pathophysiology of sub-

stance use disorders (SUD), and ADHD occurs more often in

populations with SUD compared to the general population. This

high prevalence rate and comorbidity may relate to a shared neu-

robiological vulnerability, including a deregulation of the brain’s

dopamine system. This comorbidity directly impacts the treat-

ment of ADHD: treatment with methylphenidate is less effective in

patients with ADHD and SUD compared to ADHD patients without



We investigate the underlying neurobiological back-

ground of reduced treatment effectiveness for adult ADHD patients

with comorbid SUD.


We observed lower available dopamine transporters, as

well as a reduced binding of methylphenidate to these transporters,

andmore neurocognitive dysfunction in adults ADHD patients with

SUD compared to ADHD patients without SUD.


Comorbid ADHD and SUD has a high prevalence

rate and reduces ADHD treatment effectiveness, which makes

it necessary to screen for the presence of ADHD in patients