European Psychiatry - Volume 41 - April 2017

640 / 916

S636 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S583–S644
Conclusions High cortisol levels may exert deleterious effects on
cognition and exacerbate AD pathology. Further studies are needed
to explore glucocorticoid-based interventions in the management
of cognitive disorders.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0714
Plastic surgery treatment of
post-bariatric patients cannot remain
“brainless”
C. Pavan ∗, V. Vindigni , A. Vallesi
1 University of Padova, Department of Medicine, Padova, Italy
2 University of Padova, Department of Neurosciences, Padova, Italy
∗ Corresponding author.
Introduction The aim of this study was to investigate the pres-
ence of executive difficulties due to a lack of the management of
cognitive conflict, inhibition, and cognitive flexibility in this group
of patients. If executive difficulties are at the basis of uncontrolled
alimentary behavior, these will be present also after a dramatic
weight loss and could led to a poor compliance of the patient after
plastic surgery procedures.
Materials andmethods We enrolled 21 consecutive post-bariatric
patients. This clinical population was compared with a control
group (n = 21) from the general population sharing the same
clinical and demographic features. Psychiatric evaluation was
performed. Executive difficulties were investigated through elec-
troencephalography using the stroop task, sustained attention to
response task, and task switching tests.
Results The patient group reported more frequently psychiatric
disorders than control group. Patients had higher prevalence of
lifetime major depression (58.3% vs. 14.3%), of lifetime panic dis-
order (36.1% vs. 4.8%) and generalized anxiety disorder (16.75%
vs. 0%). Finally, patients were more frequently affected by body
dismorphic disorder (chi2 = 8.867, P = .003). Electroencephalogra-
phy confirmed the presence of executive difficulties sustained
by a lack of the control of cognitive conflict and cognitive flex-
ibility, and a difficulty of the inhibitory control in the patient
group.
Conclusion Electroencephalography confirmed for the first
time the high prevalence of psychological/psychiatric prob-
lems in post-bariatric patients. Patients showing high values of
executive difficulties will need a psychological/psychiatric sup-
port to sustain a positive outcome after post-bariatric plastic
surgery.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0715
Cognitive functions recovery after
traumatic brain injury of mild severity
in adolescents
S. Pervichko
Lomonosov Moscow State University, psychology, Moscow, Russia
Introduction The effect of the traumatic brain injury of mild
severity (mTBI) on the cognitive functions influences on the edu-
cational activities of adolescents in school and the quality of life in
general.
Objectives To study the violations and to track the dynamics of
recovery higher mental functions (HMF), after mTBI in adolescents
with neuropsychological syndrome in the range of up to one year.
Materials and methods The study is based on the original set of
techniques designed by A.R. Luria. We focused on assessing the
status of various components of the HMF. We also studied of the
mental activity in its regulatory and dynamic aspects. Thirty-one
patients with mTBI (mean age was 11.5 + 1.3) and 20 healthy sub-
jects (mean age was 12 + 1.5) took part in the study.
Results Analysis of the results showed that violations of HMF in
the acute periodwere represented by three types of syndromes. The
leading place in each syndrome is occupied by deficiency symptoms
of non-specific brain structures. Research of dynamics of recovery
HMF demonstrated the symptoms related to deficiency of parietal-
temporal-occipital area are reducing for the first month, as well as
the symptoms of the anterior brain. After six months we observed
the decrease all symptoms from cortical structures, but the symp-
toms persist in the form of fatigue, reduction the rate of mental
activity, difficulty in concentration.
Conclusions Application of neuropsychological approach (Luria
school) to the diagnosis and recovery of deficit cognitive function
allows to describe the symptoms and to identify their hierarchy in
the structure of violations.
Disclosure of interest The author has not supplied his declaration
of competing interest.
EV0716
Phenocopy frontotemporal dementia:
A case series from a national memory
clinic and a review of the literature
C. Power ∗, O. Hannigan , M. Gibb , I. Bruce , M. McCarthy ,
R. Coen , D. Robinson , B.A. Lawlor
1 St James’s Hospital, Memory Clinic – Mercer’s Institute for Research
in Ageing, Dublin, Ireland
2 Memory Clinic, Mercer’s Institute for Research in Ageing, Dublin,
Ireland
∗ Corresponding author.
Introduction The existence of a frontotemporal dementia pheno-
copy (phFTD) syndrome remains controversial. Opinions differ on
whether the phenocopy presentation represents the neuropsychol-
ogical manifestation of a mid-life decompensation in vulnerable
pre-morbid personalities or an indolent prodrome of behavioral-
variant FTD (bvFTD). Literature on this topic is sparse and clinicians
and patients have little guidance around prognosis and manage-
ment.
Objectives To describe the demographic, neuropsychological and
biomarker profiles of a case series of phFTD patients, attending the
memory clinic and review relevant literature.
Methods Retrospective reviewof all cases diagnosedwith phFTD.
Results Eleven cases were identified (male = 9, female = 2). Mean
age 55.8 years. Subjective complaints comprised memory and lan-
guage difficulties. Collateral reports described apathy, aggression,
impulsivity, disinhibition, hyperorality. Function was relatively
preserved though motivation or supervision for higher-level tasks
was sometimes required. All had non-neurodegenerative MRI and
PET scans. Neuropsychological test (NPT) findings predominantly
showed executive dysfunction and fluency impairment. A total of
3/11 had non-amnestic memory impairment. Follow-up imaging
andNPTwere invariably unchanged; 1/11 had a pre-morbid psychi-
atric diagnosis; 5/11 had unusual personality traits pre-morbidly.
Major psychosocial stressors were documented in 7/11. Manage-
ment consisted of psychosocial interventions to support function
and interpersonal relationships.
Conclusions The literature describes the phFTD syndrome as pre-
dominantly affecting males though we include 2 females whomeet
the criteria. In keepingwith our findings, personality traits and psy-
chosocial stressors may be more common in phFTD than bvFTD.
More severe symptoms, memory impairment at presentation and
C9ORF72 gene mutation may predict eventual progression. Those
who do not progress have minimal long-term functional impair-
ment though behavioral symptoms persist.