European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S710–S771 S765
schizophrenia and in affective disorder patients. Nevertheless,
these findings are still controversial.
Objectives Set up a system to record and evaluate the eye move-
ments in psychiatric patients.
Aims To verify the applicability of a smooth pursuit task in a
sample of psychiatric inpatients and to prove its efficiency in dis-
criminating patient and control group performance.
Methods A sample of psychiatric inpatients was tested at psychi-
atric service of diagnosis and care of AUSL Romagna-Cesena. Eye
movement measures were collected at a sampling rate of 60Hz
using the eye tribe tracker, a bar plugged into a PC, placed below
the screen and containing both webcam and infrared illumination.
Subjects underwent to a smooth pursuit eye movement task. They
had to visually follow a white dot target moving horizontally on a
black backgroundwith a sinusoidal velocity. At the end of the task, a
chart of the eye movements done is shown on the screen. Data are
off-line analyzed to calculate several eye movement parameters:
gain, eye movement delay with respect to the movement of the
target, maximum speed and number of saccades exhibited during
pursuit.
Results Patients compared to controls showed higher delay and
lower gain values.
Conclusions Findings confirm the adequacy of this method in
order to detect eye movement differences between psychiatric
patients and controls in a smooth pursuit task.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1109
Affective disorders, psychosis and
lipid levels: Is there a connection?
Linking psychopathology, clinical
exams and neurobiology
M. Nascimento ∗ Lázaro eis Pereira acelar
A. Nobre
1 Centro Hospitalar Psiquiátrico de Lisboa, Clínica 5, Affective
Disorders and OCD, Lisbon, Portugal
2 Centro Hospitalar do Algarve, Psiquiatria, Faro, Portugal
3 Centro Hospitalar Psiquiátrico de Lisboa, Clínica 4, Lisbon, Portugal
∗ Corresponding author.
Introduction Published research regarding the relationship
between lipid levels in affective disorders has been contradictory.
Additionally, most studies correlating psychosis to lipid serumcon-
centrations only concern schizophrenic patients.
Objective To access the relationship between serum lipid levels
with the diagnosis and pathophysiology of affective disorders.
Methods Diagnostic data (ICD–10: F31–32), including mood and
psychotic features, were prospectively collected for all patients
admitted at the affective disorder ward at Centro Hospitalar
Psiquiátrico de Lisboa (Portugal), during the third trimester of 2016.
Serum concentrations of triglycerides and total/HDL/LDL choles-
terol were evaluated using standard laboratory tests. Statistical
analysis was performed for possible correlations between serum
lipid levels and:
– different stages of bipolar disorder (BD);
– elevated versus depressive mood (unipolar and bipolar);
– depressive mood (BD versus non-BD);
– psychotic features.
Results Sixty-three patients admitted were enrolled in this
study: 47 presented with BD (32 manic, 10 depressives and 5
mixed episodes) and 16 presented depressive disorders. Statisti-
cal analysis (R software) revealed that depressed bipolar patients
had significantly higher triglyceride (P = 0.026), total and LDL
cholesterol (P= 0.525) levels than other states; mixed episodes
presented higher HDL levels (P = 0.542). Although not significant,
manic patients’ HDL levels were consistently elevated compared
to depressive ones, whom presented with lower values overall.
Finally, when adjusted for age, psychotic patients showed lower
levels of total (P = 0.031) and LDL cholesterol (P = 0.052) compared
to non-psychotic patients.
Conclusions There is a potential link between serum lipid lev-
els and diagnosis/psychopathology of affective disorders. Further
research is needed to characterize its pathophysiologic relevance.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1110
Coping, schemas and cardiovascular
risks – Study protocol
M. Slepecky ∗, J. Prasko , I. Majercak , E. Gyorgyova ,
A. Kotianova , M. Zatkova , M. Chupacova , I. Tonhajzerova ,
M. Popelkova , M. Kotian
1 UKF NItra, psychology, Liptovsky Mikulas, Slovak Republic
2 Pavol Josef Safarik University in Kosice, Department of Internal
Medicine, Kosice, Slovak Republic
3 Psychagogia, psychology, Liptovsky Mikulas, Slovak Republic
4 Faculty of Medicine, Jesenius Medical Faculty, Department of
Physiology, Martin, Slovak Republic
∗ Corresponding author.
Introduction According indicators from the OECD in 2015, car-
diovascular diseases remain the main cause of mortality in most
OECD countries. But main risk factor, as smoking, obesity, hyper-
tension or physical activity do not explain that Slovak republic was
the worst fromOECD countries with number 404 age-standardized
rates per 100,000 population.
Objectives Determinewhichpsychological, psycho-physiological
and anthropometrics factors are at risk of cardiovascular diseases:
Aim The aim is to determine, which risk psychological, psycho-
physiological and anthropometricsmarkers are remarkable in time,
when individual subjectively perceives himself as health. Based on
the analysis of these correlates will be identified predictors, medi-
ators and moderators of the cardiovascular diseases from the area
of psychological variables, which accentuates the clinical picture
of a patient with cardiovascular disease. Another aim is to identify
specific risk factors for target advice on a lifestyle modification and
creation of an interdisciplinary methodology for the prevention of
cardiovascular diseases.
Methods Project is aimed to clarify the relation between psycho-
logical factors (measuring by personal inventories as temperament
predispositions, maladaptive schemes, coping, personality char-
acteristics), balance of autonomic nervous system (by measuring
HRV, skin conductance, muscle tension, respiration, and sur-
face temperature), anthropometrics characteristics (BMI, weight,
height) with potential symptoms of cardiovascular diseases con-
firmed in cardiac evaluation (12-lead ECG), blood pressure,
examination of pulsewave, and data of arteriographic examination.
Conclusions The results of the study can help to the better
understanding of the interface between psychological factors and
cardiovascular problems, which help to find new diagnostic, pre-
ventive and treatment approaches.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.