European Psychiatry - Volume 41 - April 2017

859 / 916

25th European Congress of Psychiatry / European Psychiatry 41S (2017) S847–S910 S855
EV1370
Personality and insomnia: The role of
gender
A.P. Amaral , M.J. Soares , A.T. Pereira ∗, S. Bos , C. Roque ,
A. Macedo
1 Institute Polytechnic of Coimbra, ESTESC, Coimbra Health School,
Coimbra, Portugal
2 Faculty of Medicine, University of Coimbra, Psychological Medicine,
Coimbra, Portugal
∗ Corresponding author.
Introduction Several epidemiological studies have been con-
ducted to document the prevalence and correlates of insomnia.
Most of them confirm their high prevalence in the general pop-
ulation, and a gender difference in the risk for insomnia.
Aims To study the role of gender in the relationship between
personality (perfectionism and neuroticism) and insomnia ([IG]
insomnia group, [ISG] insomnia symptoms group, and [GSG] good
sleepers group).
Methods A total of 549 college students (80.1% females) filled in
theMPS (Frost et al., 1990; Hewitt and Flett, 1991), EPI (Barton et al.,
1992, 1995), and a self-reported questionnaire to assess insomnia
symptoms.
Results No differences were found between female and male
samples, concerning the dimension of perfectionism– doubts about
actions. The IG and the ISG showed higher levels of doubts about
actions than the GSG. However, only in female sample the IG and
the ISG showed higher levels of concern over mistakes in compari-
son with the GSG. In males, no significant differences between the
sleep groups were found, in which respects concern over mistakes.
The level of extroversion was higher in the GSG, but only in male
sample. In females, there were no significant differences between
the sleep groups in relation to extroversion.
Conclusions No gender differences were found for the role of
doubts about actions in insomnia. Only in females, the dimen-
sion – concern over mistakes is important in insomnia, and only
in males the dimension – extroversion is important to have a good
sleep. These results warrant further research.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1371
Use of buspirone in selective
serotonin reuptake inhibitor-induced
sleep bruxism
V. Prisco ∗, T. Iannaccone , G. Di Grezia
1 University of Naples SUN, Department of Psychiatry, Naples, Italy
2 University of Naples SUN, Department of Radiology, Naples, Italy
∗ Corresponding author.
Sleep bruxism is characterized by the involuntary clenching
or grinding of the teeth during sleep and can cause severe
health problems, including the destruction of tooth structure,
temporo-mandibular joint dysfunction, myofascial pain, and severe
sleep disturbances. Iatrogenic sleep bruxism may be common
during treatment with psychotropic medications, such as anti-
psychotics and antidepressants, especially selective serotonin
reuptake inhibitors (SSRIs). Bruxism is a common movement dis-
order that affects 8–21% of the population. The majority of bruxism
symptoms are mild or moderate, although rare but severe cases
may lead to serious periodontal damage, temporo-mandibular dys-
function, sleep disturbances, jaw pain, and stiffness. As a result,
such cases must be treated with medication. It has been hypoth-
esized that the mechanism of SSRI-induced bruxism may involve
excessive serotonergic action on the meso-cortical neurons aris-
ing from the ventral tegmental area. It has been argued that,the
addition of buspirone, was necessitated by the high level of resid-
ual anxiety. As a result, these symptoms may have been prevented
through the use of buspirone alone. Buspirone, is an agonist of
the 5-HT1A receptor that increases dopaminergic neuron, firing in
the ventral tegmental area and increases the synaptic release of
dopamine in the prefrontal cortex. These effects ameliorate drug-
induced bruxism. Buspirone can also ameliorate extrapyramidal
side effects, such as akathisia and tardive dyskinesia, and this prop-
erty may be an additional explanation for the bruxism-related
effects of the drug. Furthermore, buspirone may be an effective
treatment for the bruxism associated with the use of these medi-
cations.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1372
Sleep disturbances, mental toughness,
and physical activity in patients with
multiple sclerosis (MS) compared to
healthy adolescents and young adults
D. Sadeghi Bahmani ∗, M. Gerber , N. Kalak , S. Lemola ,
P.J. Clough , P. Calabrese , E. Holsboer-Trachsler , S. Brand
1 University of Basel Psychiatric Hospital, Center for Affective, Stress
and Sleep Disorders ZASS, Basel, Switzerland
2 University of Basel, Department of Sport, Exercise and Health, Sport
Science Section, Basel, Switzerland
3 Psychiatric Clinics of the University of Basel, Center for Affective,
Stress and Sleep Disorders, Basel, Switzerland
4 University of Warwick, Department of Psychology, Coventry, United
Kingdom
5 Manchester Metropolitan University, Department of Psychology,
Manchester, United Kingdom
6 University of Basel, Faculty of Psychology, Neuropsychology and
Behavioral Neurology Unit, Basel, Switzerland
∗ Corresponding author.
Background Multiple sclerosis (MS) is the commonest chronic
autoimmune demyelinating and inflammatory disease of the CNS,
afflicting both body and mind. Typical symptoms are fatigue,
paraesthesia and depression, along with cognitive impairments.
Whereas there is extant research on fatigue, depression, and cogni-
tive impairment of patients with MS during the clinical course, no
research focused on sleep, psychological functioning, and physical
activity (PA) at themoment of the diagnose. The aims of the present
study were therefore to assess possible state markers of mental
toughness (MT) as a dimension of psychological functioning, sleep
disturbances (SD), PA among patients at the moment of the diag-
nose, and to compare these data with those of healthy adolescents
and healthy young adults.
Methods A total of 23 patients with recently diagnosed MS
(M= 32.31 years), 23 healthy adolescents (M= 17.43 years), and 25
healthy young adults (M= 20.72 years) took part in the study. They
completed questionnaires covering socio-demographic data, MT,
SD, and PA.
Results Patients with MS reported similar MT traits as adoles-
cents, and an equal amount of moderate PA and SD as young adults.
Further, patients reported a lower level of vigorous PA, compared
to healthy adolescents and young adults.
Conclusions Compared to healthy adolescents and young adults,
patients at the moment of the diagnose of MS reported similar MT
traits, SD and moderate PA. The pattern of results suggests that at
the moment of the diagnose MS is not predictable by poor MT, poor
sleep, and decreased level of moderate PA.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.