European Psychiatry - Volume 41 - April 2017

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S128 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S106–S169
tive functioning which has become disorganised, aiding a gradual
return of the cohesion of ego and self and in some cases, cessation
of psychotic symptoms.
Methodology An observational study of one year on a group of ten
adolescents aged 17 to 20 in institutional and private settings with
psychotic manifestations and functioning. The group were tested
at the start and end of the study using WAIS-IV and MMPI-A.
Results The adolescents recruited showed a faster recovery of the
cohesive processes of their fragmented ego as well as a quicker
resumption of social relations. Our model provided an organis-
ing function and a flexible yet secure ‘container’ (Bion, 1988) for
the young people’s psychic structure. The tests showed a demon-
strable improvement in their verbal comprehension, visual-spazial
reasoning, fluid reasoning, working memory and processing speed.
Conclusions Psychotic manifestations occurring in adolescence
may decrease with an immediate integrated and rehabilitative
intervention, without need of an institutional psychiatric setting. In
conclusion, we find that “psychosis” in adolescence is a prognosis
and not a diagnosis.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0068
Pregnancy and cord vitamin D status
and symptoms of autism spectrum
disorders in toddlers: An Odense child
cohort study
S.S.B. Clausen ∗, H.T. Christesen , C. Dalgård , S. Lykkedegn ,
P. Munk-Jørgensen , N. Bilenberg
1 Institute of Clinical Research- University of Southern Denmark,
Child and Adolescent Psychiatric Department, Odense C, Denmark
2 Hans Christian Andersen Children’s Hospital, Odense University
Hospital, Odense, Denmark
3 Environmental Medicine, University of Southern Denmark,
Department of Public Health, Odense, Denmark
4 Psychiatric Department, Odense University Hospital, Odense,
Denmark
5 Institute of Clinical Research, Child and Adolescent Psychiatric
Department, Odense, Denmark
∗ Corresponding author.
Introduction Vitamin D deficiency is widespread globally in
pregnant women and is suggested to contribute to offspring risk
of symptoms of autism spectrum disorders (ASD), but findings are
inconsistent.
Objectives To investigate whether low prenatal 25OHD exposure
and 25OHD status in early life increase risk of early symptoms of
ASD.
Aims To investigate early signs of ASD.
Methods From the prospective birth cohort, Odense child cohort
(n = 2.549), Denmark, we included singletons with their mothers
with available serum concentrations of 25OHD at early pregnancy
(n = 1.231), late pregnancy (n = 1.361), and birth (n = 2.082). ASD
symptoms were rated by parents on the pervasive developmen-
tal problem (PDP) scale of the Child behavior checklist for ages
1½-5 (CBCL 1½-5). Associations between 25OHD and PDP score
were analyzed by multiple linear and logistic regression models.
A priori included covariates were gestational age, child gender,
birth weight, season of birth, parity, parental psychiatric diagnoses,
maternal age, smoking habits, alcohol consumption, education
level, vitamin D supplementation, and pre-gestational BMI.
Results Means (SD) of 25OHD for early pregnancy, late preg-
nancy, and cord were 65.5 (21.5), 78.7 (27.0), and 47.0 (21.7)
nmol/L, respectively. PDP data were obtained at a mean (SD) of 2.7
(0.6) years of age. Data from the regression analyses are pending.
Conclusions In this well-off cohort with relatively high levels of
cord 25OHD, power calculations allows us to detect a true change
of 0.02 PDP scores per 10 nmol/L change in 25OHD. Further studies
will clarify whether early PDP scores track later ASD diagnosis.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0069
Psychiatric assessment of cases with
self-inflicted poisoning in a sample of
Egyptian children and adolescents
H. El Rafei∗ Ghanem , H. Gamaluddin , M.M. Mohamed ,
A.M. Abdel Samiee’ , N. Shaker
Psyhciatry Institute, Ain Shams University, Cairo, Egypt, Psychiatry
Department, Cairo, Egypt
∗ Corresponding author.
Introduction Suicide in children and adolescents is commonly
underreported and studied. It is an interplay area of multiple static
(sociodemographic), and modifiable (impulsivity, psychiatric mor-
bidities, adverse life events (ALE), abuse, bullying) variables.
Objectives and aim To assess and identify relative significance of
dependent and independent risk factors in youngsters attempting
self-inflicted poisoning.
Methods Consecutive recruitment of patients aged 7–18, with
normal IQ, admitted to poison control centre over 13 continu-
ous months, with self-induced poisoning. All were assessed after
guardians’ written informed consent for different risk factors iden-
tified for suicidal behavior using appropriate scales (PPS, SRRS-Y,
FSSCS, BIS-11, J-TCI, Mini-Kid). Controls with no history of suicidal
attempt were matched for age, sex and sociodemographics among
their families.
Results One hundred and twenty cases (16.7 years ± 1.6 SD, 91%
females) and 100 controls (age 16.4 years± 1.7 SD, 90.8% females)
were assessed. In cases, 90.8% were of low/middle socioeconomic
status, 73.5% had previous attempt, average within 10 months,
17.5% planned their attempt, 10.8% had a witnessed attempt.
Stressor within 2 days was reported in 75.9%, severe in 40%. Impuls-
ivity was more in its cognitive, planning and motor components
(P = 0.001 in each) among attempters. Cases scored more on Nov-
elty seeking, harmavoidance and reward dependence than controls
who had more persistence, self-directedness and cooperativeness.
Attempters had significantlymore pastmedical and psychiatric his-
tory (P = 0.001, 0.05 respectively), 77.5% had a working psychiatric
illness, 2% in controls.
Conclusion Repeated suicidal attempts were the majority, with
impulsivity as a predictive risk, especially if psychiatric morbidity
or ALE in youths were encountered.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0070
Families of children with autism
spectrum disorders: Communication
and mental health
F.D. Fernandes∗ eticia
University of São Paulo, FMUSP, Cotia-SP, Brazil
∗ Corresponding author.
Persons with autism need special care during all life and therefore
the caretakers need attention too. Parental stress in families with
children with autism is significantly higher than the observed in
families with children with other disorders or with typical devel-
opment. Communication is specially affected in autism, is one of
parent’s first concerns and may increase stress. This study asked if
parents of non-verbal children with autism have higher levels of
stress than parents of verbal children with autism. The purpose