European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S170–S237 S203
EW0285
Substance-induced psychotic
disorders in an emergency
department
A. Fernandez-Quintana ∗, A. Novo-Ponte , C. Quiroga-Fernandez ,
M.D.C. Garcia-Mahia
Psychiatry, Clinical University Hospital of La Coru˜na, La Coru˜na,
Spain
∗ Corresponding author.
Introduction Substance abuse has been correlatedwith psychotic
disorders albeit more accurate details on causality remain to be
assessed. Furthermore, the prevalence and prognosis of substance-
induced psychotic disorders have not been clearly established.
Method Retrospective study performed in 124 patients assessed
in an Emergency Department (ED) due to psychotic symptoms over
a 6-month period. Medical records were reviewed to obtain clinical
and socio-demographic variables.
Objectives (1) To analyse substance abuse patterns among
ED psychotic patients; (2) to estimate the prevalence of
substance-induced psychotic disorders in ED; (3) to underpin the
socio-demographic and clinical variables associated.
Results Personal history of substance abuse: THC 31.5%, alcohol
29%, cocaine 18.5%, benzodiazepines 18.5%, opiates 6.5%, MDMA 4%,
amphetamines 3.2%, hallucinogens 2.4%. Accumulated time inter-
val of substance abuse prior to psychotic onset: 0–5 years 15% (3.9%
developed psychosis during the first year of cannabis use), 5–10
years 9.2%, more than 10 years 20.8%. Urine testing for drug mis-
use undertaken in 80.6% of cases: positives 53%, negatives 47%.
Among positive urine test results: THC 16.5%, benzodiazepines
16.5%, cocaine 6.1%, opiates 5.1%, alcohol 0.9%, amphetamines 0.8%,
hallucinogens 0.8%. Substance-induced psychotic disorder (F19.15)
was diagnosed among 20.4% of patients. This diagnosis was 1.5
times more prevalent among males. Forty-eight percent of patients
were single, 36% married, 12% divorced, 4% widowers. Habitat: 68%
urban, 34% rural. Highest prevalence group 36 – 50 year olds.
Conclusions Both substance abuse and substance-induced psy-
chotic disorders are highly prevalent in our sample. Their
socio-demographic and clinical profile is similar to that found in
schizophrenia. Further refinements of these findings arewarranted.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0286
Cannabis-induced psychotic disorders
and THC use among patients with
psychotic symptoms
A. Fernandez-Quintana ∗, C. Quiroga-Fernandez , A. Novo-Ponte ,
M.D.C. Garcia-Mahia
Psychiatry, Clinical University Hospital of La Coru˜na, La Coru˜na,
Spain
∗ Corresponding author.
Introduction Causality between THC and psychotic symptoms
has been outlined in several studies and a potential role for THC
in the development of Schizophrenia remains to be assessed.
Methods Retrospective study undertaken in a sample of 124
patients assessed in an Emergency Department (ED) due to psy-
chotic symptoms. Medical records were reviewed to obtain clinical
and sociodemographic variables.
Objectives (1) To analyse the prevalence of THC consumption
among psychotic patients in ED; (2) to establish the preva-
lence of cannabis-induced psychotic disorder; (3) to underpin the
socio-demographic and clinical variables associatedwith cannabis-
induced psychosis.
Results Personal history of cannabis use 31.5% (6.5% as a single
drug.) Accumulated time interval of cannabis use prior to the first
psychotic episode: 0 – 5 years 15% (3.9% developed psychosis dur-
ing the first year of cannabis use), 5 – 10 years 9.2%, more than
10 years 20.8%. Cannabis-induced psychotic disorder (F12.5) was
diagnosed in 3.3% of the sample. The prevalence of this diagno-
sis was the same among male and female patients. The highest
prevalence of cannabis-induced psychosis was found among 36–50
years old patients (50%). All patients with a diagnosis of Cannabis-
induced psychotic disorder had a personal history of THC use and
urine tests had been positive for THC in 75% of the cases. Habitat:
75% urban, 25% rural. Marital status: 50% single, 50% married.
Conclusions Cannabis use is highly prevalent among patients
who present with psychotic symptoms in ED and THC is corre-
lated with psychotic episodes. The prevalence of cannabis-induced
psychosis has also increased. Further studies comprising larger
samples are warranted.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0287
Evolutionary aspects of psychotic
disorders induced by cannabis
F. Guermazi ∗, R. Ennaoui , N. Halouani , S. Chouayakh , J. Aloulou ,
O. Amami
Psychiatry, Hedi Chaker university hospital, , Sfax, Tunisia
∗ Corresponding author.
Introduction Cannabis is increasingly used by young people. Its
several noxious effects on mental health have become a matter of
preoccupation. Although cannabis use may be involved in the eti-
ology of acute psychosis, there has been considerable debate about
the association observed with chronic psychosis.
Aims (1) To describe the profile of patients with cannabis use
disorders (CUD); (2) to determine the evolutionary aspects.
Methods We proceed with a retrospective and descriptive study
conducted among 16 male patients with CUD and hospitalised for
the first time in the psychiatric department at the University Hos-
pital Hedi Chaker during the period from 1 January 2012 to 31
December 2014.
Results An overwhelming majority of the subjects were single
and unemployed. One-third of the users had a stay abroad, the half
was incarcerated at least once and one patient was implicated in
illegal drugs trade. CUD were associated with specific personality
disorders: borderline (18.8%) and antisocial (6.3%) personality. Into
at least the 2 years of follow-up, different evolutionary aspectswere
distinguished. Many of the patients were lost to follow (18.8%). A
total restitution of symptoms or a recurrence of the same disorders
were observed in 25% of cases. About 56.3% of subjects had a change
in diagnosis to either schizophrenia (43.3%) or affective disorder
(12.5%).
Conclusion This study showed that cannabis use can be a cause
of the emergence of chronic psychosis. This emphasizes the impor-
tance of early screening of the vulnerability to psychotic disorder
and identify more effective strategies to improve intervention.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0288
Video and Internet gaming addiction
among young adults
F. Guermazi ∗, N. Halouani , K. Yaich , R. Ennaoui , S. Chouayakh ,
J. Aloulou , O. Amami
Psychiatry, Hedi chaker university hospital, Sfax, Tunisia
∗ Corresponding author.
Introduction With the popularity of high-tech devices and Inter-
net use in recent years, playing online or offline games has become