European Psychiatry - Volume 41 - April 2017

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S210 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S170–S237
EW0305
Exploring the complex association
between affective temperaments and
suicidal behaviour
G. Serafini ∗, G. Canepa , G. Adavastro , M. Pompili ,
P. Girardi , M. Amore
1 University of Genoa, Neuroscience DINOGMI, Genoa, Italy
2 Sant’Andrea Hospital- Suicide Prevention Center, Sapienza
University of Rome, Neurosciences, Rome, Italy
3 Sant’Andrea Hospital, Sapienza University of Rome, Neurosciences,
Rome, Italy
∗ Corresponding author.
Introduction Suicidal behaviour is one of themost relevant public
health problems and it is associatedwith a significant disability and
psychosocial impairment. Affective temperaments, hopelessness,
suicidal ideation, and suicide intent may be significantly involved
in suicidal behaviour.
Objectives The present study explored the complex relation
between these clinical variables and suicide.
Aims We aimed to evaluate the specific role of affective tem-
peraments and other risk factors as potential predictors of suicide
risk.
Methods The sample included 276 patients (19.9% men, 81.1%
women; mean age: 48.1 years, SD:16.9), of which most with major
affective disorders, who were admitted at the Psychiatric Unit of
the University of Genoa (Italy). All participants have been eval-
uated using the Temperament Evaluation of Memphis, Pisa and
San Diego Auto-questionnaire (TEMPS-a), Beck Hopelessness scale
(BHS), Scale for Suicide Ideation (SSI), and Intent Score Scale (ISS).
Results Patients with anxious temperament significantly differ
in terms of residual interepisodic symptoms, substances abuse,
adherence to treatment, and current episode duration when com-
pared with those having other affective temperaments. Only
suicidal ideation and irritable temperament resulted significant
predictors of suicide preparation. In addition, suicidal ideation and
prior suicide attempts represent significant predictors of suicide
intent.
Conclusions The present findings suggest the importance of sys-
tematic evaluation for suicidal behaviour that may allow clinicians
to identify patients at higher suicide risk. As these data may be
influenced by the severity of the psychopathological conditions
and psychiatric medications, which were used during admission
by our patients, further additional studies are needed to test these
preliminary findings.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0306
Childhood traumatic experiences and
coping strategies: Correlations with
quality of life
G. Serafini ∗, C. Conigliaro , F. Pittaluga , M. Pompili ,
P. Girardi , M. Amore
1 University of Genoa, Neuroscience DINOGMI, Genoa, Italy
2 Sant’Andrea Hospital, Suicide Prevention Center, Sapienza
University of Rome, Neurosciences, Rome, Italy
3 Sant’Andrea Hospital, Sapienza University of Rome, Neurosciences,
Rome, Italy
∗ Corresponding author.
Introduction Individuals with a history of childhood traumatic
experiences may exert maladaptive coping strategies and impaired
adult quality of life.
Objectives The present study explored the association between
childhood traumatic experiences, coping strategies, and quality of
life.
Aims We aimed to evaluatewhether childhood traumatic experi-
ences or specific coping strategies may significantly predict quality
of life.
Methods This is a cross-sectional study including 276 patients
(19.9% men, 81.1% women; mean age: 48.1 years, SD: 16.9), of
which most with major affective disorders, who were recruited at
the psychiatric unit of the university of Genoa (Italy). All partic-
ipants were assessed using the Childhood Trauma Questionnaire
(CTQ), Coping Orientation to Problems Experienced (Cope), and
Short Form 12 Health Survey version 2 (SF-12).
Results Subjects with a history of emotional abuse were more
likely to have an earlier age of onset of their psychiatric condi-
tions, an earlier age of their first treatment/hospitalization, higher
recurrent episodes and days of hospitalization, longer illness dura-
tion and non-psychiatric treatments at intakewhen comparedwith
those who did not present any history of abuse. Based on regression
analyses, only positive reinterpretation and growth, focus on and
venting of emotions, and substance abuse, but not childhood trau-
matic experiences, resulted positive predictors of physical quality
of life. Moreover, focus on and venting of emotions was able to
predict mental quality of life.
Conclusions While traumatic experiences did not predict quality
of life, specific coping strategies were significant predictors of qual-
ity of life. Further studies are requested to test these preliminary
results.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0307
Platelet and plasmatic lipidic profile
as potential marker of bipolar
disorders: Preliminary findings
L. Sideli ∗ ule’ amiani Corso ontana
M. Caprin Colli i Giacomo Catalano Greco
F. Di Gaudio La Barbera
1 Section of Psychiatry, Experimental Biomedicine and Clinical
Neuroscience, Palermo, Italy
2 Medical Biotechnologies and Legal Medicine, University of Palermo,
Palermo, Italy
∗ Corresponding author.
Introduction Although the diagnosis of bipolar disorder is cur-
rently based on clinical criteria, preliminary studies showed that
palmitic and arachidonic acid levels are able to discriminate adult
patients with major depressive disorder (MDD) from those with
bipolar disorder (BD).
Objectives To replicate and to expand previous findings by inves-
tigating the relation between mood disorders and platelet and
plasmatic fatty levels.
Aims To compare the lipidic profile of individuals with different
mood disorder (MDD vs. BD) and to investigate the relation with
specific clinical features (duration of illness, attempted suicide, psy-
chotic symptoms).
Methods Potential participants were recruited from the outpa-
tient and inpatient psychiatric units of the university hospital of
Palermo (Italy). Diagnosis of DSM IV mood disorders was made
using the MINI. Symptom severity was assessed using the HAM-
D rating scale and the YMRS. Fatty acid profile was analyzed using
mass spectrometry.
Results Preliminary analyses were performed on 8 patients with
MDD and 6 with BD. Groups were similar in terms of demo-
graphic variables. Patients with MDD showed highest levels of
platelet palmitic acid, stearic acid, and arachidonic acid. Further-
more, plasmatic docosahexaenoic acid was negatively related with
manic symptoms severity (Rho = –0.697; P = 0.025) and platelet
alpha linolenic acid was positively related with illness duration
(Rho = 0.845; P = 0.040).