European Psychiatry - Volume 41 - April 2017

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S216 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S170–S237
EW0324
Cognitive, emotional and personal
features of children with cleft lip and
palate
I. Mandel ∗, S. Mikheev , A. Mandel
1 A.V. Vishnevsky Institute of Surgery, ICU, Moscow, Russia
2 Research Institute of Cardiology, Tomsk National Research Medical
Center of RAS, cardiosurgery, Tomsk, Russia
3 Mental Health Research Institute, Tomsk National Research Medical
Center of RAS, addictive disorders, Tomsk, Russia
∗ Corresponding author.
Introduction Cognitive and behavioural problems usually accom-
pany isolated clefts of the lip and/or the palate (ICLP)
Aims To investigate cognitive, emotional and personal features
of children with ICLP in comparison with non-cleft children from
complete families and non-cleft orphans.
Methods The ICLP group consisted of 29 children (age 14.2 ±0.7).
The first comparison group (1CG) consisted of 34 non-cleft chil-
dren (age 14.1 ±0.5). The second comparison group (2CG) consisted
of 30 non-cleft orphans (age 13.8 ± 0.8). Drawing tests “House-
Tree-Person” have been selected to evaluate the level of children’s
development, emotional and personal features in all three groups.
M. Luscher Color test was chosen to figure out the children’s psy-
chological state, regardless of education level.
Results The most characteristic features of the ICLP children and
2CG were similar. They included infantilism (69%; 43.3%), low
self-control (65.5%; 56.7%), demonstrative demeanor (62%; 36.7%),
escape from reality into fantasy (93%; 76.7%), anxiety (69%; 63.3%).
ICLP children compared with the 1CG has shown significantly
higher level of aggression (79.3% vs. 4.2%), increased self-esteem
(59.6 vs. 4.2%), impulsiveness (51.7% vs. 16.7%), the importance of
other people’s opinions (59.6% vs. 29.2%). Contrary, the feelings of
lack of emotional warmth, the need for protection were observed
in 1CG more frequently–70.8% vs 55.2% in ICLP and 60% in 2CG.
Conclusions Psychological correction in children with ICLP
should be aimed at increasing the adaptive functions, facilitating
communication with peers, search the area for self-realization.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
Reference
[1] van der Plas E, Koscik TR, Conrad AL, et al. J Clin Exp Neuropsy-
chol 2013;35(5):489–500.
EW0325
Prenatal and perinatal factors in
autism spectrum disorders–a case
control study of a Serbian sample
V. Mandic-Maravic ∗, M. Pejovic-Milovancevic ,
M. Mitkovic-Voncina , D. Lecic-Tosevski
1 Institute of Mental Health, Department for psychotic disorders,
Belgrade, Serbia
2 Institute of Mental Health, Head, Child and adolescent clinic,
Belgrade, Serbia
3 School of Medicine, University of Belgrade, Department of
psychiatry Belgrade, Serbia
4 Institute of Mental Health, Day hospital for adolescents, Belgrade,
Serbia
5 Institute of Mental Health, Director, Belgrade, Serbia
6 Serbian Academy of Sciences and Arts, Department of Medical
Sciences Belgrade, Serbia
7 School of Medicine, University of Belgrade, Head, Department of
psychiatry Belgrade, Serbia
∗ Corresponding author.
Introduction Autism spectrum disorders (ASD) are complex psy-
chiatric disorders, with both genetic and environmental factors
implicated in their etiology. Recent studies suggest the prenatal and
early postnatal genesis of ASD, therefore, understanding the effect
of environmental risk factors could be important for prevention and
treatment of ASD.
Aims The aim of this study was to determine the association of
prenatal factors and perinatal complications with ASD.
Methods Our study included 102 subjects with ASD (80% boys)
aged 9.35 ±5.85, and 107 age and sex matched healthy controls
(77% boys). For the diagnosis of ASD, we used the ICD-10 criteria
and Autism Diagnostic Interview-Revised (ADI-R). A questionnaire
regarding prenatal and perinatal factors/complications was admin-
istered to all subjects.
Results Logistic regression model of having autism vs. being a
control subject included gender, age, maternal and paternal age
at birth, pregnancy order, smoking in pregnancy, number of med-
ication during pregnancy (mostly tocolytics, antihypertensives,
antiarrhythmics), and early postnatal complications (mostly pre-
maturity, low birth weight, hyperbilirubinaemia). The model was
significant, explaining about the third of variance, with number of
medication during pregnancy and having an early postnatal com-
plication as significant predictors.
Conclusions Our study has shown a significant association of spe-
cific prenatal and perinatal factors and ASD, even after controlling
for other potential confounding variables. Identifying specific risk
factors is important for prevention of ASD. It is also the first step
in defining basis of the gene–environment interaction mechanism,
which might enable development of an individualised therapeutic
approach for this group of disorders.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0326
Sensory processing disorders and
psychopathology
J. Mesquita Reis ∗ ueiróga , R. Velasco Rodrigues ,
B. Pinto Ferreira , F. Padez Vieira , M. Farinha , P. Caldeira da Silva
Dona Estefânia Hospital, Child and Adolescent Psychiatry, Lisboa,
Portugal
∗ Corresponding author.
Introduction Sensory processing is the individual’s ability to
receive, process and integrate sensory information from the envi-
ronment and body movement in the central nervous system, in
order to produce adaptive responses. Sensory processing disor-
ders (SPD) are associated to difficulties in regulating emotions
and behaviours as well as motor abilities in response to sensory
stimulation that lead to impairment in development and function-
ing. It is estimated that SPD affect 5–16% of school-aged children.
Although these diseases constitute a primary diagnostic category
in the Diagnostic Classification of Mental Health and Development
Disorders of Infancy and Early Childhood: DC0-3, they have not yet
been validated by the Diagnostic and Statistical Manual of Men-
tal Disorders-DSM. In the latest edition of DSM, SPD were only
included as one of the diagnostic criteria of autism-spectrum dis-
orders. However, several studies have suggested that SPD may
present themselves solely or coexist with other clinical conditions.
Objective The aim of this study was to review systematically the
relationship between SPD and psychopathology.
Methodology Articles indexed in the Pubmed database were ana-
lyzed.
Results/conclusion Although sensory processing problems are
well known to occur in association with autism, their relationship
with other mental disorders is not a well studied area. Some studies
have related them with ADHD, behavioural disorders and learning
disorders. Some studies also comproved that SPD are a valid diag-
nosis and that there are individuals with SPD who do not meet the
criteria for other known disorder. One study found an abnormal