European Psychiatry - Volume 41 - April 2017

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S252 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S238–S302
of survivorship care. Screening for mental health morbidity should
be better integrated into active cancer treatment and survivorship
and it should be provided mental health later interventions.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0427
The impact of the type of surgical
treatment on the quality of life of
Portuguese women with breast cancer
H. Pereira ∗ astelo
University of Beira Interior, Psychology and Education, Covilhã,
Portugal
∗ Corresponding author.
Introduction Breast cancer significantly impacts dimensions of
quality of life such as mental health, one’s level of activity, fam-
ily well-being, physical concerns (symptoms and pain), treatment
satisfaction, emotional well-being, sexual intimacy, and social
functioning.
Aim The aim of this study is to evaluate the impact of the type
of surgery on the quality of life of women being treated for breast
cancer, based on the comparison of samples of women who have
undergone different types of surgery.
Method Our sample consists of 90 Portuguese women divided
into three groups of 30 participants each. The first group under-
went radical surgery inorder to treat their breast cancer. The second
group of women had conservative surgery as a breast cancer treat-
ment. Finally, the last group of women did not have any type of
surgical intervention. We use a socio-demographic questionnaire
and the Portuguese version of the EORTC QLQ-30 as measurement
instruments. The sample consists of patients froma central hospital
in Lisbon, Portugal, and the data were collected anonymously.
Results We find that in all dimensions of quality of life measured,
including general health, physical functioning, social roles, and all
emotional, cognitive, and social dimensions, the group of women
who underwent radical surgery shows lower scores when com-
pared to the other two groups. This indicates that this group has
lower levels of quality of life.
Conclusion The use of surgery for the treatment of breast cancer
leads to a diminished quality of life following surgical intervention.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0428
Quality of life and anxious-depressive
symptoms in cancer patients
undergoing mindfulness-based
interventions: Feasibility and
preliminary outcomes on prospective
single-centre case-control study
(MIND4ME St.)
G. Pontoni ∗ Maur errari Guida oletti
F. Caggia ontana avioli arantino ascinu
S. Ferrari
1 University of Modena and Reggio Emilia, Department of Diagnostic
Medicine- Clinic and Public Health, Section of Psychiatry, Modena,
Italy
2 University of Modena and Reggio Emilia, Department of
Hematology and Oncology, Modena, Italy
3 Centro Studi ASIA Bologna, Associazione ASIA, Modena, Italy
4 University of Padua, FISPPA Department, Section of Applied
Psychology, Padua, Italy
5 University of Modena and Reggio Emilia, Department of Medical
and Surgical Sciences Maternal-Infantile and Adult, Modena, Italy
∗ Corresponding author.
Background Mindfulness based interventions (MBIs) have shown
efficacy in improving psychological symptoms including depres-
sion and anxiety in cancer patients (pts). The study aimed to explore
feasibility and reproducibility of MBIs in an Italian Cancer Centre
measuring biochemical and psychological parameters.
Methods In this pilot prospective case-control study, we
recruited newly diagnosed pts receiving adjuvant chemotherapy
(CT). A MBIs program was designed consisting of 2.5 hours weekly
for 8 weeks and, including meditation, yoga and body scan. Mate-
rial for 45minutes (mn) home daily practice was provided. Primary
endpoint was to evaluate feasibility. Secondary endpoints were
assessment of quality of life (QoL), psychological and biochemical
outcomes of stress, tested at baseline (W0), W4, W8, W24, W48. PSS
(Perceived Stress Reduction), POMS (profile of mood states scores),
EuroQoL (EQ-5D-3L) were administered.
Results Ten pts underwent MBIs program arm. We present pre-
liminary results, while data of control arm are being collected.
All pts were female, two pts (20%) dropped out. Median age
was 56 years. All received adjuvant CT, 5/8 received radiotherapy
and hormone therapy. Mean of sessions attending was 6.8 (76%).
Median daily practice was 30 mn. EQ-5D item for depression and
anxiety showed decreasing trend in mean score from moderate to
light (P = 0.15) and significant improvement of auto-perceived QoL
was observed comparing W0 and W8 (P = 0.02)
Conclusions In a sensitive setting such as start CT, we found high
pts compliance to MBIs. Improvement in self-perceived QoL after
starting program was found and comparing anxious-depressive
symptoms outcomes with control arm is still needed.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0429
Psychosocial interventions to improve
the quality of life for men with
prostate cancer: A network
meta-analysis of 31 randomized
controlled trials
S. Qiu ∗, D. Linghui
1 West China Hospital Sichuan University, Urology, Chengdu, China
2 Stroke Clinical Research Unit, Department of Neurology, West China
Hospital, Sichuan University, Chengdu–Sichuan. China, Department
of Neurology, Chengdu, China
∗ Corresponding author.
Background The treatment of prostate cancer (PCa) can trigger a
sequence of life-altering decisions that can induce depression and
effects onhealth-relatedquality of aimed to simultaneously
compare all available psychosocial interventions using both direct
and indirect data.
Methods In this systematic review and network meta-analysis,
we searched the Embase, Medline, PsycINFO, and the Cochrane cen-
tral register of controlled trials for randomized controlled trials
(RCT) published before Oct, 2016, that compared active treat-
ments dealing with psychosocial problems in PCa patients after
treatment. The primary outcome was health-related quality of
life improvement as measured by the 36-Item Short-Form Health
Survey (SF-36). Psychologicalmorbiditywas assessedwith theHos-
pital Anxiety and Depression Scale (HADS). This study is registered
with PROSPERO, number CRD42016049621.
Results We screened 113 potentially eligible studies and identi-
fied 31 RCTs, that examined 7 psychosocial interventions in 3643
PCa participants. In terms of SF-36, cognitive behavioral therapy
[standard mean difference (SMD) 2·48, credible interval [CrI] 0.23