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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S238–S302

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.


Pain perception in children with

autism (prospective study of 40 cases)

A. Kachouchi

1 ,

, S . S

aid (Dr)

1 , P.O

.N. Fadoua

2 , P.A

. Benali

2 ,

P.A. Imane

1 , P.M

. Fatiha

1 , P.A

. Fatima



University hospital Mohammed VI, Department Of Psychiatry,

Marrakech, Morocco


Avicenne military hospital, Chlid and adolescent psychiatry service,

Marrakech, Morocco

Corresponding author.


Recent studies show a different mode of expression

of pain associated with disorders of verbal and nonverbal commu-

nication, body schema and some cognitive impairment in autistic


The aim of our study was to evaluate the reactivity of an autistic

child in a slightly painful stimulation in a standardized situation

where there is a dual relationship with an adult.


We conducted a study, on 40 children with autism. The

diagnosis of autism was established following a multidisciplinary

assessment including scale ADIR (Autism Diagnostic Interview

Revised) and ADOS (Autism Diagnostic Observation Schedule).

Severity of autism was assessed by the CARS (Childhood Autism

Rating Scale). All subjects were submitted to a pinchwith a clothes-

pin camouflaged by the palm of the hand of the examiner. The

reactivity to pain was assessed by the NCCPC (Non-communicating

children’s pain checklist).


All children have responded to pain, 57.5% had moder-

ate to severe pain and 42.5% had mild pain. The evaluation of the

expression of pain according to the items of the NCCPC showed that

95% of children responded with motor responses, 90% responded

with vocal productions, only half of the children (55%) presented

facial expressions and 12. 5% of the children showed physiological

indices. The analysis of the type of motor and vocal reactions was

not moving toward pain in almost all children (removal or protec-

tion of the area of the body affected, the precise location of the

painful area are almost absent in our sample).


These results are in favor of a different mode of

expression of pain in children with autism.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.


Mental disorders in patients with

temporomandibular pain-dysfunction


V. Medvedev

, V. Frolova , Y. Fofanova

PFUR University, Chair of Psychiatry- Psychotherapy and

Psychosomatic Pathology, Moscow, Russia

Corresponding author.


Maxillofacial surgeons and dentists often deal

with the phenomenon of temporomandibular pain-dysfunction

syndrome–painful condition of maxillofacial area without clear

organic pathology. Psychiatric studies of this disorder are almost

lacking. The aim of this study was to determine the prevalence of

psychiatric disorders in patients with temporomandibular pain-

dysfunction syndrome and to define the psychiatric diagnosis



Study sample consists of 57 patients (44 women and 13

men) with temporomandibular pain-dysfunction syndrome aged

older than 18 years, who gave inform consent. The study used clin-

ical psychopathological, psychometric (HADS, HDRS, State-Trait

Anxiety Inventory, Hypochondria Whitley Index, Visual Analog

Scale for Pain).


Psychiatric disorderswere revealed in 48 patients (84.2%)

with temporomandibular pain-dysfunction syndrome–39 women

and 9 men aged 18-65 years (mean age 39.6


15.4 years). Affec-

tive disorders was diagnosed in 56.3%, personality disorders in

20.8%, schizotypal personality disorder in 12.5% and schizophrenia

in 10.4%. Among affective pathology mild and moderate depressive

episodes prevailed (59.3%). The severity of pain (VAS) in patients

with affective disorders was higher than in patients with other

psychiatric conditions.


This study shows high prevalence of psychiatric

disorders in patients with temporomandibular pain-dysfunction

syndrome and proves the feasibility of a psychiatrist participate

in the complex treatment of these patients. The use of psychome-

tric method allows to improve the timeliness of the detection of

patients who require further clinical psychopathological examina-

tion in order to determine the need of pharmacotherapy.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.


Burning mouth syndrome: Problem in

the mouth?

S. Petrykiv

1 ,

, L. de Jonge


, M. Arts



University Medical Center Groningen, Department of Clinical

Pharmacy and Pharmacology, Groningen, The Netherlands


Leonardo Scientific Research Institute, Department of Geriatric

Psychiatry, Groningen, The Netherlands


University Medical Center Groningen, Department of Old Age

Psychiatry, Groningen, The Netherlands

Corresponding author.


Burning mouth syndrome (BMS) is characterized by

an intraoral burning sensation for which nomedical or dental cause

can be found. Sporadic evidence suggests that drug induced con-

ditions may evoke BMS. Intriguingly, we observed a patient who

developed BMS after induction of citalopram.

Objectives & aims

A case report of patient with BMS from our

psychiatric ward will be presented here, followed by a literature

review on drugs induced BMS.


Based on a recent literature search, we present a first

case report of BMS that was apparently induced in patient shortly

after beginning of citalopram. We performed a systematic search

through PubMed, EMBASE and Cochrane’s Library to find more

cases of psychotropic induced BMS.


Ms. A. was a 72-year old woman meeting DSM-IV diag-

nostic criteria for melancholic depression, who was observed in a

clinical setting. We started citalopram 10mg. 1dd1, with 10mg.

1dd1 increase over 7 days to 20mg, 1dd1. The following day, she

displayed a persistent burning painful sensation in the mouth.

Other than BMS oropharyngological syndromes were excluded

after consultation with qualified medical specialists. Citalopram

therapy was discontinued, and nortrilen treatment was initiated.

BMS symptoms resolved over four days. Twelve case reports have

linked BMS to the use antidepressants and anxiolytics.


Contrasting the statement that no medical cause can

be found for BMS, we found that psychotropics may evoke the

syndrome. Compared to other psychotropic drugs, antidepressant

medication has the strongest association with BMS.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.