European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S8–S52 S23
S050
The NYMPHA-MD project: Next
generation mobile platforms for
health, in mental disorders
M. Faurholt-Jepsen
Rigshospitalet - Copenhagen university hospital, psychiatric center
Copenhagen, Copenhagen, Denmark
Bipolar Disorder is a common and complex mental disorder with
a prevalence of 1-2% and accounts as one of the most important
causes of disability at age 15-44 years worldwide.
Electronic versions of self-monitoring tools and symptom regis-
tration using computers, personal digital assistants (PDAs), text
messages, and web interfaces have been described in the litera-
ture and a large number of commercial Smartphone applications
for patients with bipolar disorder are available.
The Next Generation Mobile Platforms for Health, in Mental Dis-
orders project (the NYMPHA-MD project), funded by the European
Union’s Seventh Framework program for research, technological
development and demonstration, focuses on the implementation of
a Pre-Commercial Procurement of mobile e-health service for sup-
porting physicians and patients in the treatment of bipolar disorder
through continuous patients monitoring in order to dynamically
support illness management and potentially identify early warning
signs.
The NYMPHA-MD project will define the framework of a Pre-
Commercial Procurement for the provisioning of next generation
services advocated for mental health treatment with a special focus
on bipolar disorder based on the use of new technologies, open
standards and open platforms.
The NYMPHA-MD project will focus on identifying requirements
involved in the structuring of mental health services with a focus
on bipolar disorder treatment including medical, technological,
patients, legal, ethical, policy, risk management and business-
orientation needs in order to construct a reference model of service
provisioning useful in different European contexts.
Disclosure of interest The author has not supplied his declaration
of competing interest.
S051
Neuropersonaltrainer-mh: A new
computerized platform for the
cognitive remediation in
schizophrenia and bipolar disorders
N. Cardoner ∗, A. Cebria , C. Lopez-Sola , M. Serra-Blasco ,
C. Massons , V. Muriel , G. Navarra , E. Via , J. Cobo ,
X. Golberg
1 Institut de Recerca Parc Taulí- I3PT, mental health, Sabadell, Spain
2 Consorci Hospitalari Parc Tauli-I3PT, mental health, Sabadell, Spain
∗ Corresponding author.
Schizophrenia and mood disorders -including unipolar depression
and bipolar disorder-, are severe mental diseases with a highly
heterogeneous symptomatology, among which cognitive dysfunc-
tion has progressively emerged as a key cornerstone. Patients
suffering from these illnesses show significant deficits in differ-
ent neurocognitive and social cognition domains. These deficits are
evident during acute episodes, and in a high percentage of patients
persist in periods of recovery, playing a decisive role on functional
and clinical outcome. Nowadays, different pharmacological ther-
apies have been tested, obtaining non-conclusive results. In this
context, non-pharmacological strategies, such as neurocognitive
remediation, have emerged as promising therapeutic intervention.
Neurocognitive remediation comprises a program to rehabili-
tate cognitively impaired subjects, aiming either to restore their
cognitive functioning or to compensate them in specific cognitive
domains. One evolving approach, beginning to receive attention
for its initial promising results, is computerized cognitive training.
This technique employs tasks or games that exercise a particular
brain function which target specific neural networks in order to
improve cognitive functioning through neuroplasticity in a given
neural circuit. In this scenario, we report our recent results with
neuropersonaltrainer® -MH; a module for neurocognitive reme-
diation consisting in a computerized telerehabilitation platform
that enables cognitive remediation programs to be carried out
in an intensive and personalized manner. Our group has applied
NPTMH® in a pilot study treating patients with early onset psy-
chotic disorder with positive and promising results, involving an
improvement in functionality, neurocognition, and social cognition
performance. Furthermore, new trials in bipolar disorder andmajor
depressive disorder have been recently started.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
Symposium: shame and guilt in clinical practice
S052
Shame & guilt: Definitions,
antecedents and structure of
experience
F. Oyebode
University of Birmingham, Birmingham, United Kingdom
Aims In this lecture I will define and distinguish between shame
and guilt. I will then discuss the potential causes of shame and guilt
and how these emotions manifest in behavioral and phenomenal
terms. I will conclude by introducing a classification that deals with
the varieties and nature of the pathologies of shame and guilt that
are evident in clinical practice. I will rely on concepts developed by
Karl Jaspers, Hans Jonas and Bernhard Schlink. In doing this I will be
exploring the role of moral and juridical principles upon the expe-
rience of shame and guilt including the place of the imperatives of
responsibility upon the experience of shame and guilt. I will argue
further that shame and guilt are as important as other secondary
emotions such as envy and jealousy but are not as examined and
studied in clinical practice. I will make a case for the centrality of
these emotions to an understanding of and response to particular
clinical conditions in daily practice.
Methods N/A.
Results N/A.
Conclusions Shame and Guilt are both important emotions that
are central to our understanding of and response to particular con-
ditions in daily practice. Their antecedents and structure provide a
basis for distinguishing between them.
Disclosure of interest The author has not supplied his declaration
of competing interest.
S053
Shame and guilt in mental disorders -
diagnostics and treatment
L. Madeira
Faculdade de medicina - universidade de lisboa, psychiatry, Lisbon,
Portugal
Guilt and shame are important human emotions, which have been
studied by several different disciplines. Seminal and recent inputs
in Psychology (particularly Psychoanalysis) and Psychiatry are