European Psychiatry - Volume 41 - April 2017

359 / 916

25th European Congress of Psychiatry / European Psychiatry 41S (2017) S303–S364 S355
of our patients developed depression, more in patients with major
neurological deficits.
Conclusions Efforts must be done for primary prevention of
stroke, early detection of risk factors and correct treatment, and
for cessation of toxic habits. Treating associated depression may
improve patients’ quality of life and increase comfort for caregivers.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0725
Inflammatory bowel disease
symptoms and cognitive fusion’s
impact on psychological health:
An 18-month prospective study
I.A. Trindade , C. Ferreira∗, J. Pinto-Gouveia
Faculty of psychology and education sciences, university of Coimbra,
CINEICC, cognitive behavioural centre for research and intervention,
Coimbra, Portugal
∗ Corresponding author.
Although inflammatory bowel disease (IBD) is known to be asso-
ciated with lower psychological health, research regarding which
specific symptoms may lead to psychological dysfunction in IBD
patients is inexistent. Further, the role played by emotion regu-
lation, including the maladaptive process of cognitive fusion, in
IBD patients’ psychological functioning is also scarcely explored in
this population. The present study aimed at filling these research
gaps. Two hundred and sixteen patients diagnosed with IBD filled
self-report instruments on an online platform in three times. These
waves of assessment occurred at baseline, and 9 and 18 months
later. Results revealed that of the 10 measured IBD symptoms,
only fatigue, bloody stools and abdominal distension at baseline
were negatively associated patients’ level of psychological health
atWave 3. Nevertheless, a hierarchical regression analysis demons-
trated that none of these symptoms were significant predictors of
psychological health measured 18 months later. When cognitive
fusion at baseline was added to the model, it became the only signi-
ficant predictor of psychological health at Wave 3, with an effect of
−0.34 (P < 0.001). These findings suggest that it is not the experience
of physical symptomatology that directly leads to lower psycholo-
gical health in IBD patients, but rather the way patients deal with
adverse internal experiences, i.e., the type of emotion regulation
involved. This study reveals cognitive fusion as a harmful process
for the determination of IBD patients’ psychological functioning.
Future studies should thus explore the meditational effect of cog-
nitive fusion in the association between IBD symptomatology and
decreased psychological health.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0726
The presence of a subthreshold autism
spectrum is associated with greater
prevalence of mental disorders in
parents of children with autism
spectrum disorders
C.C.C. Gesi∗, A. Lagomarsini , F.M. Barberi , A. Guzzetta ,
S. Calderone , G. Cioni , F. Muratori , L. Dell’Osso
Department of clinical and experimental medicine, university of Pisa,
Pisa, Italy
∗ Corresponding author.
Introduction Autism spectrum disorders (ASD) are highly heri-
table and first degree relatives (especially fathers) of autistic
probands have been shown to often manifest a set of subthreshold
autistic features. It is not known, however, the clinical significance
of this subthreshold autism spectrum.
Objectives – to evaluate the prevalence of a subthreshold autism
spectrum respectively in fathers andmothers of childrenwith ASD;
– to describe clinical correlates of parents with and without a sub-
threshold autism spectrum respectively.
Methods 36 fathers and 39 mothers of preschoolers with ASD
were administered the autism-spectrum quotient (AQ), the adult
autism subthreshold spectrum (AdAS spectrum), the trauma and
loss spectrum (TALS), the SCID-5 and the social and occupational
functioning assessment scale (SOFAS).
Results Fathers and mothers did not differ for both AQ and AdAS
spectrum total and subscale scores. Overall, 13 parents (17.3%) sco-
red higher than 45 on the AdAS spectrum, as indicative of the
presence of a subthreshold autism spectrum. This group showed
greater prevalence of mood, anxiety and feeding/eating disorders,
greater utilization of antidepressants and higher scores on the TALS
and the SOFAS than the group scoring lower than 45 (all P < 0.05).
Conclusions Fathers and mothers of children with ASD show
autistic traits in equal measure. The presence of a subthreshold
autism spectrum is associated to greater prevalence of mood,
anxiety and feeding/eating disorders, to greater susceptibility to
traumatic events and to lower levels of functioning.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0727
Developing a test to assess social
cognition based on a real interaction
G. Benito , C. Luzón , J. Arillaga , A. Fernández-Liria ,
G. Lahera ∗
1 INTRAS foundation, mental health, Burgos, Spain
2 Private practice, psychology, Madrid, Spain
3 Príncipe de Asturias university hospital, psychiatry, Alcalá Madrid,
Madrid, Spain
4 University of Alcalá, psychiatry, Alcalá Madrid, Madrid, Spain
5 University of Alcalá, psychiatry, Alcalá de Henares, Madrid, Spain
6 CIBERSAM, mental health, Madrid, Spain
∗ Corresponding author.
Introduction Social cognition enables the processing of social
information and is needed to adapt one’s behaviour to the percei-
ved social scene. Its assessment is a very controversial issue, tests
currently available often use unhelpful stimuli from the ecological
point of view.
Aims To develop a test based on genuine social stimuli–not on
their representations–and to do so, a controlled social situation is
created in which participants can be evaluated on their abilities to
perceive and process such information.
Method A script was prepared, consisting of several interactions
which are staged before the participants by two members of the
research team. The sample comprises 50 subjects, being on average
22 years old (56% women), who took this test, the MSCEIT and the
MASC.
Results The application showed no incidence, no one detected
that it was a previously prepared situation and they were not upset
when this fact was revealed. A final selection of 18 items obtained
a reliability of 0.701. Multidimensional scaling, partly showed the
subdomains taken into account. The correlation matrix confirms
the validity of the instrument. (r= 0,465 alpha < 0,001 with MASC.
r= 0,106 alpha > 0,05 with MSCEIT).
Conclusions The instrument is applicable and tolerated by par-
ticipants being evaluated with it. It is feasible to use it as a test
to assess social cognition It is mid-high reliability allows its use
for research purposes. The correlation matrix confirmed validity,
showing a significant and moderate connection with MASC and no
association with any of the scales of MSCEIT.