European Psychiatry - Volume 41 - April 2017

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S358 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S303–S364
EW0734
Gender differences in overgeneralized
autobiographical memory in survivors
of torture with posttraumatic stress
disorder
V. Giannouli ∗, S. Popa
1 Aristotle university of Thessaloniki, school of medicine, Drama,
Greece
2 State university of Moldova, faculty of psychology and educational
sciences, Chis¸ in˘au, Moldova
∗ Corresponding author.
Introduction Persons suffering fromPTSD show less episodic spe-
cificity in recalling autobiographical memories producing what is
often referred to as “overgeneralized memories” as it is shown by
scientific studies.
Objective In this research, we are focusing our attention on whe-
ther this phenomenon is the same for both men and women or it
shows gender specificity.
Method The rehabilitation center for torture victims “Memoria”
provided information about people who have recently experienced
torture. Some of these victims of torture volunteered to participate
in the current research. The participants were assessed with the
Harvard trauma questionnaire in order to identify whether they
suffer from PTSD or not. A sample of 40 torture survivors with PTSD
was selected for the research–20men and 20women. The age range
is between 20 and 45. On a computer screen, we presented the cue
words with the task to recall a past event and time period (month
or 5–20 years). The participants pressed a computer key indicating
when an event had been recalled, and then, it was described in an
audio recorder. The responses were scored 3 for a specific event, 2
a repeated over time event, 1 a general event, 0 none.
Results Both sexes revealed a significant correlation between
specificity for autobiographical memories and episodic simula-
tions, only in case of women this correlation is higher compared
with men (r = 0.83 P < 0.001).
Conclusions Further research is needed in order to eliminate cau-
salities and to extend the results on other populations.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0735
Neuroeconomic approach to trauma
related psychopathology: A version to
ambiguous losses in PTSD
I. Harpaz-Rotem ∗, R. Jia , L. Ruderman , R. Pietrzak , I. Levy
1 Yale university, psychiatry, New Haven, USA
2 Yale university, interdepartmental neuroscience program, New
Haven, USA
3 Yale university, comparative medicine, New Haven, USA
4 Yale university, comperative mediciane and neuroscience, New
Haven, USA
∗ Corresponding author.
Psychiatric symptoms typically cut across traditional diagnostic
categories. In order to devise individually-tailored treatments,
there is a need to identify the basic mechanisms that underlie these
symptoms. Behavioral and neuro-economics methods provide a
framework for studying these potential mechanisms. We utilized
this framework to examine aspects of trauma-related symptoma-
tology and its potential link to individual uncertainty attitudes. We
distinguish between attitudes towards uncertain outcomes with
known (“risk”) and unknown (“ambiguity”) probabilities, and bet-
ween attitudes towards uncertain gains and uncertain losses. fMRI
data were obtained from57 combat veterans (30 with PTSD, and 27
without PTSD) who made choices involving risky and ambiguous
options, which were used to estimate risk and ambiguity attitudes
in the gain and loss domains. Veterans with PTSDwere more averse
to ambiguity, but not risk, compared to veterans without PTSD,
when making choices between possible losses, but not gains. The
degree of aversion was associated with anxious arousal symptoms,
as well as with the degree of combat exposure. Awhole brain analy-
sis indicated association between activation in specific brain areas
implicated in decision-making and severity of PTSD. Moreover,
ambiguity attitudes fullymediated the association between combat
exposure and anxious arousal symptoms. These results provide a
foundation for the causal association between ambiguity attitudes
and trauma-related symptoms, as well as etiology of the neural
underpinnings of these behavioral outcomes. Results demonstrate
the potential of neuroeconomic and behavioral economic tech-
niques for devising objective and incentive-compatible diagnostic
tools, and investigating the etiology of psychiatric disorders.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0736
Trauma and the unborn child:
PTSD, major depression and
relationship quality following late
pregnancy loss
D. Horesh ∗, M. Nukrian , Y. Bialik
1 Bar Ilan university, psychology, Ramat Gan, Israel
2 Hadassah Ein-Karem medical center, obstetrics and gynecology,
Jerusalem, Israel
∗ Corresponding author.
Background and objective Late pregnancy loss (PL) is recogni-
zed as a very difficult life experience. Often, PL is regarded as a
“feminine” trauma, experienced individually by the woman, thus
neglecting the role of the parental dyad in coping with the loss. This
study aimed to examine:
– the prevalence of PTSD and major depressive disorder (MDD)
following late PL;
– the role of spousal relationship measures in vulnerability and
resilience following PL.
Methods Participants were 100 women, ages 24–49 (M= 35.07,
SD = 5.28), who have experienced late PL. The mean pregnancy
week of loss was 27.29, with the average woman being 22 months
post-loss. 84.6% experienced stillbirth. Participants completed self-
report questionnaires assessing PTSD, MDD, dyadic adjustment and
dyadic self-disclosure.
Results We have found high rates of both PTSD (32.7%) and MDD
(53%) among women following late PL, as well as high PTSD-MDD
comorbidity rates. Interestingly, a negative association was found
between the number of previous pregnancy losses and the severity
of MDD, perhaps indicating an innoculation process. Both PTSD and
MDD were negatively associated with the levels of dyadic consen-
sus, dyadic self-disclosure regarding guilt and shame, and dyadic
affectional expression.
Conclusions Late PL entails a heavy burden of PTSD and MDD,
presumably since mothers are already strongly attached to their
unborn child. PL is often experienced by both expecting mother
and father. Thus, the quality of the spousal relationship following
PL is an important protective factor. Therefore, there is a pressing
need for novel interventions in couples therapy following PL.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.