European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S303–S364 S359
EW0737
Impact of emotional and cognitive
saliency on visual search in
post-traumatic stress disorder
E. Kiesmann ∗, P. Grandgenèvre , J. Mallet ,
C. Dubertret , G. Vaiva
1 SCALab, UMR CNRS 9193, university of Lille, department of
psychiatry, CHRU de Lille, Lille, France
2 Universitary hospital Louis-Mourier, Colombes, France
3 Unversity Paris Diderot, department of psychiatry, Lille, France
4 Inserm U894, center of psychiatry and neurosciences, department of
psychiatry, Paris, France
∗ Corresponding author.
Introduction Patients with post-traumatic stress disorder (PTSD)
have shown disturbances in visual information treatment. Howe-
ver, most of studies demonstrated attentional bias towards
emotional stimuli by using non-ecological paradigm. The paradigm
of change blindness offers the possibility of studying sensitivity to
the sudden irruption of visual information with ecological stimuli.
Objectives/Aims To compare the explicit detectionwith the impli-
cit detection by using respectivelymotor response and eye tracking
in patients with PSTD and controls.
Methods Fifteen patients with PTSD and fifteen healthy controls
had to detect changes in 96 scenes with (1) no change, (2) one neu-
tral change or (3) one emotional pleasant or unpleasant change.
We measured the participant’s speed and accuracy in explicitly
reporting the changes via motor responses, and their capacity to
implicitly detect changes via eye movements.
Results The patients showed a trend towards slower explicit
detection for the emotional change (P = 0.06) and more specifically
for unpleasant change (P = 0.054). The two groups did not differ for
implicit detection.
Conclusion Patients tend to explicitly detect more slowly emo-
tional change (but not neutral), especially for unpleasant change.
This could be the result of a lack of access to consciousness of
the emotional information. The emotional visual information treat-
ment in PSTD could require more attentional processes than the
non-emotional visual information and then lead to a decrease of
the available attentional resources for the explicit task.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0738
Comparison of ten-years risk of fatal
cardiovascular events calculated by
heartscore in diabetic patients with
and without post-traumatic stress
disorder (PTSD) comorbidity
N. Lucev ∗, A. Vuk , I. Simunovic Filipcic , I. Filipcic
1 Psychiatric hospital Sveti Ivan, department of psychiatry, Zagreb,
Croatia
2 The university hospital centre Zagreb KBC Zagreb, department of
psychological medicine, Zagreb, Croatia
∗ Corresponding author.
Introduction Cardiovascular diseases (CVD) are the leading cause
of death and disability-adjusted life years lost globally. Recent
studies have shown that post-traumatic stress disorder (PTSD)
predicts higher risk of cardiometabolic diseases, specifically car-
diovascular disease and diabetes type 2.
Aims To assess cardiovascular event risk differences between
diabetic patients with and without PTSD comorbidity.
Objectives To explore a ten-year risk of fatal CVD events in dia-
betic patients with and without PTSD; to gain better insight in
potential different functioning patterns in these patient subgroups.
Methods We investigated a cross-sectional sample consisting of
390 psychiatric inpatients and outpatients. Ten-years risk of fatal
CVD events calculated by HeartScore, European society of cardio-
logy. Europe high-risk version was used. The risk estimation is
made based on: gender, age, smoking, systolic blood pressure and
total cholesterol.
Results By analysis of covariance, we controlled possible
confounding effects of gender, age, education, marital status, num-
ber of household members, work status, average monthly income
per householdmember, bodymass index (kg/m2), number of soma-
tic comorbidities, number of psychiatric comorbidities, duration of
PTSD, clinical global impression scale–severity of PTSD at diagno-
sis. After the adjustment for all these variables, interaction of PTSD
and T2DM was significantly associated with CVD risk (P< 0.001;
Eta2 = 0.04).
Conclusion A significant fatal CVD event risk differences between
diabetic patients with and without PTSD comorbidity were found.
Better awareness of possible underlying determinants provides
better optimal individual approachplanning, likewise effective pre-
vention and control of cardiovascular diseases.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0739
Benefits of EMDR therapy on the
memory in the treatment of PTSD
S. Sassi Andrade Vieira , M. Di Giorgio , E. Cohen , M. Caurand ,
A. Manchon , A. Quaderi , J. Palazzolo∗
Université de Nice, psychology, Nice, France
∗ Corresponding author.
According to some studies, 80% of subjects suffering from
post-traumatic stress disorder (PTSD) present twice the risk of
developing an insanity as they age because of the high level of
stress that has been induced. Indeed, the triggered trauma has
a deleterious effect on the establishment of the stress’ axis (the
hypothalamic pituitary adrenal axis) which is then not able to
regulate itself. As a consequence, the hippocampal neurons will
be attacked by an excess of cortisol. Memory’s dysfunction is cen-
tral in the symptomatology of PTSD, particularly in respect to
encoding and recall. The hippocampus is able to transfer informa-
tion to the prefrontal cortex. Actually, subjects with PTSD present
less activity in the prefrontal cortex triggered by a decrease of
encoding and recall capacities. EMDR therapy (eye movement
desensitization and recruitment) allow for a fast relief of symp-
toms by a bilateral alternate stimulation (SBA). Indeed, saccadic
eye movements stem affect related to the traumatic event and pro-
cess the associated cognitions. During the desensitization phase in
EMDR, we noticed an increase in activity of the brain’s prefrontal,
ventromedial, amygdala and thalamic regions. Indeed, the recall
of traumatic memories goes through implicit emotional valence
regions and associative areas for which the experience is already
deeply integrated. After comparing cerebral activity before and
after the therapy, researches on EMDR shows that a reduction of
stress’ symptoms has some sensitive link to PTSD (in prevention to
dementia).
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0740
Embitterment in war veterans with
posttraumatic stress disorder (PTSD)
D. Sabic ∗, A. Sabic
1 Psychiatric association of Bosnia-Herzegovina, health centre
Zivinice, Tuzla, Bosnia, Herzegovina