European Psychiatry - Volume 41 - April 2017

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25th European congress of psychiatry / European Psychiatry 41S (2017) S365–S404 S383
Disclosure of interest The author has not supplied his/her decla-
ration of competing interest.
EW0803
Using junior doctors to improve
patient care: Creating a clinic to
monitor the physical health of
patients prescribed clozapine
M. Tonkins , P. Hardy , S. Foster ∗, S. Mullins
Sheffield Health and Social Care NHS Foundation Trust, West
Community Mental Health Team, Sheffield, United Kingdom
∗ Corresponding author.
Introduction In the United Kingdom, compliance with guidelines
on physical health monitoring of patients prescribed clozapine is
poor. Our community team established a ‘clozapine clinic’, led by
junior doctors, to monitor the physical health of this population.
Aims The aims of this audit were:
– to ascertain levels of compliance with guidelines on the physical
health monitoring of patients taking clozapine;
– to compare the current level of compliance with that prior to the
establishment of the clinic.
Methods Eleven standards were drawn from National Institute
for Health and Care Excellence guidelines and the Maudsley Pre-
scribing Guidelines in Psychiatry.
Three audit cycles were conducted: two prior to the establishment
of the clinic and one after. In each cycle, searches of patient records
were conducted and blood results were reviewed. This was sup-
plemented by telephone calls to general practitioners to ensure a
complete data set.
Analysis was conducted inMicrosoft ExcelTM and changes between
the cycles were analysed using a two-tailed Z-score.
Results Each audit cycle included 28–30 patients. In the current
cycle compliance levels varied between 66% (annual ECG recording)
and 100% (monthly full blood count). The average compliance level
was 73% across all standards. This represents an overall improve-
ment on previous audit cycles. Since the clinic was established
there has been a statistically significant improvement in compli-
ancewith annual monitoring of weight ( P = 0.147), bodymass index
(P = 0.0178), and ECG monitoring (P = 0.0244).
Conclusions Improvements in the care of a vulnerable population
may be achieved through setting clear standards, regular audit, and
harnessing the leadership and enthusiasm of junior doctors.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0804
Enhancement of flexible cognition in
autism
C. Varanda , F.D.M. Fernandes∗
University of São Paulo, Department of Physical Therapy, Speech,
Language Pathology and Audiology, and Occupational Therapy, São
Paulo, Brazil
∗ Corresponding author.
Autism is defined by qualitative deficits in communication, social
interaction and restricted patterns of interests and behavior. There
are also reported difficulties in the dynamic activation and mod-
ification of cognitive processes in response to changes in tasks
demands. It is assumed that poor flexible cognition is related to
those difficulties. This research aimed to assess and intervene in
cognitive flexibility in subjects with autism.
Ten subjects diagnosed with autism by psychiatrists, aged 5y to
13y5m, were assessed in cognitive flexibility through WCST in
pretest and in patterns of social interactions, behaviors and com-
munication through ADI-R. An intervention program with 14 to 21
sessions designed to enhance cognitive flexibility through activities
of local coherence inference, constructive praxis, attentional shift-
ing, inhibitory control, besides drama games after reading stories.
In posttest, they were assessed in WCST and ADI-R. Raw scores of
categories completed and perseverative errors and responses were
used.
Regarding flexible cognition, perseverative errors and responses
were lower in posttest (P = 0.028). Categories completed were
improved in posttest (P = 0.049). Total scores on ADI-R were lower
in posttest (P = 0.051) and as well as scores on communication abil-
ities (P = 0.033).
The qualitative improvement showed by the individuals of
this research concerning flexible cognition and also patterns of
restricted behavior, social interaction and communication abilities
suggests that individuals with autism can benefit from the devel-
opment of strategies for the rehabilitation of flexible cognition and
more research is suggested with a larger sample among subjects on
the autism spectrum.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
e-Poster Walk: Schizophrenia and other psychotic
disorders – Part 5
EW0805
Awareness of and satisfaction with
available treatment options in
schizophrenia: Results from a survey
of patients and caregivers in Europe
P. Cherubin ∗ aria argarter Wooller
1 Janssen, Medical Affairs, Issy-les-Moulineaux, France
2 Janssen, Communication & Public Affairs, Bucharest, Romania
3 Janssen, Medical Affairs, Neuss, Germany
4 Janssen, Medical Affairs, High Wycombe, United Kingdom
∗ Corresponding author.
Introduction Understanding beliefs and concerns of patientswith
schizophrenia and their caregivers, regarding treatment options, is
key to improving their care. Perceived fears can impact adherence
to therapy and represent a barrier to prescribers when discussing
treatment decisions.
Objectives Explore patient and caregiver awareness of and satis-
faction with available treatment options.
Methods Independent market research agency commissioned by
Janssen, performed an online European survey in 2016 to capture
demographics, awareness of available therapies, current treatment
satisfaction and adherence from patients with schizophrenia and
caregivers.
Results Results from 166 patients with schizophrenia and 468
caregivers from 12 European countries (France, Germany, UK, Italy,
Spain, Denmark, Russia, Sweden, Austria, Belgium, Switzerland,
and the Netherlands). One-fifth of patients reported they have not
discussed alternative treatment options with their healthcare pro-
fessional (HCP) despite 37% of patients being dissatisfied or very
dissatisfied with their current therapy. HCPs were considered as
the primary information source for the majority of patients (73%),
although 27% of patients and 25% of caregivers believed that HCPs
were not fully aware of all available treatment options. Moreover,
68% of patients treated with oral antipsychotics confirmed they
would consider switching to a long-acting antipsychotic treatment,
though 32% reported they have not been made aware of it as an