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S390

25th European congress of psychiatry / European Psychiatry 41S (2017) S365–S404

ment Questionnaire, Internalized Stigma of Mental Illness Scale,

Temperament and Character Inventory, Adult Dispositional Hope

Scale, Drug Attitude Inventory, Liebowitz Social Anxiety Scale, Beck

Depression Inventory – II, and Beck Anxiety Inventory.

Results

The quality of life was significantly higher in employed

patients, and individuals with higher hope, self-directedness, and

persistence. The quality of life was lower among the patients with

higher number of hospitalizations, thosewith higher severity of the

disorder and individuals who were taking more medication. The

patients with more pronounced symptoms of depression, anxiety,

and social anxiety had a lower quality of life. Finally, the quality of

life was lower among the individuals with higher harm avoidance,

and self-stigmatization.

Conclusions

Detection of the quality of life in the context of per-

sonality traits, hope, self-stigma and demographical and clinical

factors may be an important part of the treatment of patients with

schizophrenia.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.02.436

EW0823

Negative aspects of self-stigma in

patients with schizophrenia spectrum

disorders

K. Vrbova

1 ,

, J. Prasko

1

, M. Ociskova

1

, M. Holubova

2

,

D. Kamaradova

1

, M. Marackova

1

, A. Grambal

1

, M. Slepecky

3

,

K. Latalova

1

1

Faculty of Medicine and Dentistry, Palacky University and

University Hospital Olomouc, Department of Psychiatry, Olomouc,

Czech Republic

2

Faculty of Medicine and Dentistry, Palacky University and

University Hospital Olomouc, Hospital Liberec, Department of

Psychiatry, Olomouc, Liberec, Czech Republic

3

Faculty of Social Science and Health Care, Constantine the

Philosopher University in Nitra, Department of Psychology Sciences,

Nitra, Slovak Republic

Corresponding author.

Introduction

Most individuals diagnosed with schizophrenia

must cope with some form of stigmatization. Different types of

public stigma, self-stigma and label avoidance, may have negative

consequences for these individuals.

Objectives

The aim of the study was to search the degree of self-

stigma in schizophrenia and its association with the clinical and

demographic factors.

Methods

One hundred and ninety-seven stabilized outpatients

diagnosed with schizophrenia spectrum disorders participated

in the study. The mean age of the sample was 40 years. All

individuals completed the Internalized Stigma of Mental Illness

Scale (ISMI) and a demographic questionnaire. The disorder sever-

ity was assessed both by a psychiatrist (objCGI-S: the objective

version of Clinical Global Impression – Severity scale) and by

the patients (subjCGI-S: the subjective version of Clinical Global

Impression – Severity scale).

Results

The total score of the ISMI positively correlated with

the severity of the disorder measured by the objCGI-S and the

subjCGI-S. Additionally, the self-stigma positively correlated with

the treatment duration, and the number of hospitalizations. The

regression analysis identified these regressors as the most relevant

to the self-stigma – the number of hospitalizations, the severity

of the disorder rated by a psychiatrist, and the difference between

the objective rating and the subjective rating of the severity of the

disorder.

Conclusions

Outpatients with psychosis, who have undergone a

higher number of hospitalizations, dispose of a higher severity of

the disorder and show a bigger discrepancy between their rating of

the severity and the psychiatric rating, display a greater degree of

self-stigma.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.02.437

EW0824

Therapy initiation during a first acute

episode psychosis in the psychiatric

department of Mahdia

B. Walid

, I. M

arrag , R. Ben Soussia , F. Ellouze , M. Nasr

Hospital, Psychiatrie, Mahdia, Tunisia

Corresponding author.

Introduction

The quality of the therapeutic care during a first

episode psychosis (FEP) determines the middle- and long-term

prognosis.

Objectives

The aim of our study is to describe the therapeutic

attitudes in front of a FEP and discuss them according to current

international recommendations.

Methods

This is a retrospective descriptive study. All patients

with a FEP, hospitalized in the psychiatric department of the uni-

versity hospital, Mahdia during the period from 15 May 2000 to 31

December 2013 have been included.

Results

We recruited 111 patients. The average age was 27

years, a male predominance was noted. Initially, the majority of

patients were treated in monotherapy (55.9%) and mostly with

typical antipsychotic drugs (80.2%), by injection. Among those

under association, 63.4% received corrective treatment and 26.8%

a benzodiazepine. The prescription of a mood stabilizer and an

antidepressant was noted in respectively 5.6 and 2.8% of cases. The

majority of patients received typical antipsychotic drugs (53.1%)

while 39.6% were under atypical antipsychotic. The follow-up

period, after which a reduction of the antipsychotic dose was

decided, ranged from 1 to 66 months with an average of 8.26.

Conclusion

The progression to a chronic psychosis, still has a

severe connotation. The Early and adequate therapeutic care in

accordance with the international recommendations, determines

the prognosis and constitute a decisivemoment in the evolutionary

trajectory of the disease.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.02.438

EW0825

Effectiveness of health checks to

improve the physical health of people

with severe mental illness in

secondary care: A single blind cluster

randomised controlled trial

J. White

1 ,

, J. Lucas

2

, L. Swift

3

, G. Barton

4

, G. Harriet

5

, L. Irvine

6

,

G. Abotsie

7

, M. Jones

8

, R. Gray

9

1

University of Hull, Faculty of Health and Social Care, Hull, United

Kingdom

2

James Paget University Hospitals NHS Foundation Trust, Research

and Development, Great Yarmouth, United Kingdom

3

University of East Anglia, Norwich Medical School, Norwich, United

Kingdom

4

University of East Anglia, Clinical Trials Unit, Norwich, United

Kingdom

5

University of East Anglia, School of Psychology, Norwich, United

Kingdom

6

University of East Anglia, Clinical Trial Unit, Norwich, United

Kingdom

7

Norfolk and Suffolk NHS Foundation Trust, Research and

Development, Norwich, United Kingdom