European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S465–S520 S471
very creative persons (VCP); mildly creative persons (MCP); slightly
creative persons (SCP). VCPs have a significantly lower level of
depression and have a better QoL compared to SCPs. MCPs have
a level of depression between the other groups and a similar level
of QoL than VCPs. These results suggest that creativity could have a
noticeable influence on how patients experience their cancer. Fur-
ther studies on this phenomenon will be necessary for creativity to
be taken into account for psychological follow-up in oncology.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0208
Temporal tumor as a cause of
bipolar-like disorder?
S. Domingues ∗, M. Cotter , I. Amado , R. Massano
1 Centro Hospitalar do Médio Tejo, Hospital de Tomar, Psiquiatria,
Leiria, Portugal
2 Centro Hospitalar do Médio Tejo, Hospital de Tomar, Psiquiatria,
Guimarães, Portugal
3 Centro Hospitalar do Médio Tejo, Hospital de Tomar, Psiquiatria,
Coimbra, Portugal
4 Centro Hospitalar do Médio Tejo, Hospital de Tomar, Psiquiatria,
Tomar, Portugal
∗ Corresponding author.
Introduction The relationship between brain tumours, temporal
epilepsy and psychiatric symptoms are historically known.
Objectives To report a case of mania in a patient with previ-
ous diagnosis of bipolar disorder, temporal tumour and temporal
epilepsy.
Methods Clinical records. Research on PubMed, using “lateral
temporal epilepsy” or “brain tumour” and “mania”.
Results A 52 years old man was conducted to the emergency
department by the police. He was found with psychomotor agi-
tation at the Sanctuary of Fátima. He was apparently hyperthimic
with flight of ideas. He had a history of epilepsy and temporal
tumour and two previous manic episodes. It was assumed as a
maniac episode.
During inpatient evaluation, patient had memory for the occur-
rence. He described a sudden onset on the day before, after drinking
wine. He described delirant atmosphere, persecutory and mys-
tic delusional beliefs “this is the third secret of Fátima being
revealed”, followed by ecstasy and psychomotor agitation. Remis-
sion was obtained in one week on psychotropics. MRI documented
the lesion. Electroencephalography performed one month later
revealed “slow waves.”
Conclusions Organic causes should be excluded before consider a
psychiatric disorder. The hypothesis of epilepsy-related psychosis
or mania and other effects of a temporal tumour should be con-
sidered in etiology. However, co morbidity with bipolar disorder
cannot be excluded.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0209
Misophonia and affective disorders:
The relationship and clinical
perspective
M. Erfanian ∗, J. Jo Brout , A. Keshavarz
1 Maastricht University, Faculty of Psychology and Neuroscience,
Maastricht, The Netherlands
2 International Misophonia Research Network, Sensory Processing
Disorder, New York, USA
3 Azad University, Psychology, Torbat-e-Jam, Iran
∗ Corresponding author.
Misophonia is characterized by aversive reactivity to repetitive
and pattern based auditory stimuli Misophonic sufferers
demonstrate autonomic nervous system arousal, accompanied
by heightened emotional distress. Sufferers describe extreme
irritation, anger, and aggressive urge with physiological reac-
tions including hypertonia, diaphoresis and tachycardia
Some studies have found comorbidity with psychiatric dis-
orders. However, most of these studies used small samples
and few experimental methodologies This study identi-
fies the possible relationship between misophonia and affective
disorders, and any difference between the severity of miso-
phonia in male and female patients. Fifty misophonic patients
(female = 25, mean age = 46.28) were evaluated with Amsterdam
Misophonia Scale (A-MISO-S) for the diagnosis of misophonia
and with the M.I.N.I International Neuropsychiatric Interview for
the diagnosis of affective disorders. Among n = 50 misophonic
patients, we found major depression (MDD) = 11, melancholic
depression = 5, dysthymia = 11, suicidality = 10, manic = 3, panic dis-
order = 8, agoraphobia = , social phobia = , obsessive compulsive
disorder (OCD) = 14, post-traumatic stress disorder (PTSD) = 15.
Misophonia was associated with MDD (U = 76, P = .001), suicidal-
ity (U = 67, P = .001), OCD (U = 115, P = .002) and PTSD (U = 142.5,
P = .008). Therewas an indicationof a significant difference between
men and women in severity of misophonia (U = 160.5, P = .002). The
presence of these varying affective disorders suggests that the suf-
ferers are at high risk for affective disorders. Investigation of the
co-morbiditywill assist researchers to better understand the nature
of the symptoms and how they may be interacting.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
References
[1] Edelstein, Brang, Rouw, Ramachandran (2013).
[2] Cavanna, Seri (2015).
[3] Schröder, Vulink, Denys (2013).
EV0210
Therapeutic patient education: A
solution to the treatment of obesity
and metabolic syndrome in psychiatry
A. Bailly , L. Fau , C. Lourioux , N. Gramaje , A. Mechain ,
A. Arnaud , F. Pillot-meunier∗
Centre Hospitalier Le Vinatier, Pole Up Mopha, Bron, France
∗ Corresponding author.
Introduction/objectives Obesity and overweight are major pub-
lic health issues. Obesity is a risk factor associated with many
non-communicable diseases such as diabetes, certain types of can-
cers, musculoskeletal disorders and cardiovascular, dermatological
or gastroenterological diseases. Patients with severe psychiatric
disorders have a higher risk of developing overweight or obesity
than the general population. The risk of obesity in schizophren-
ics patients can be multiplied by a factor ranging from 2.8 to 3.5.
Patients suffering from mood disorder have sightly lower risk of
obesity, however we still consider a factor ranging from 1.2 to 1.5.
This significant weight gain can be partly explained by medication.
Methods The hospital centre Le Vinatier, in France, has devel-
oped a therapeutic patient education program in helping patients
to self-manage their preventable disease. In order to tackle themul-
tifaceted nature of obesity, the programused the expertise of many
different professionals: general practitioners, dieticians, dentists,
physical adapted education teachers, pharmacists, nurses and so
on. This programme is provided for patients suffering from obesity
or an overweight complicated by diabetes, or/and metabolic syn-
drome, and/or history of cardiovascular diseases or/and a failure
of a dietary monitoring. The program includes individual care and
collective workshops in nutrition, oral heath, body image, adapted
physical education, and roundtable.