European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S465–S520 S467
The average suicide attempts were 3.08 for patients with addictive
behaviors and 2.00 for patients without SUD.
The association between SUD and the number of suicide attempts
was not significant (P = 0.375).
The means of suicide attempts used were drugs in 12% of cases,
3% of cases by phlebotomy, 3% of cases by hanging, 3% of cases
immolation, 2% of cases of organophosphate ingestion, 3% of cases
by defenestration, 3% of cases by the precipitation front of a vehicle
and 1% of cases by drowning.
Conclusions Co-morbid SUD in individuals with BD is signif-
icantly associated with suicide attempts. Individuals with this
co-morbidity should be targeted for intensive suicide prevention
efforts.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0195
Intellectual developmental disorders,
autism, and schizophrenia spectrum:
New boundaries in the
neurodevelopmental perspective
M. Bertelli ∗, L. Salvador-Carulla , R. Keller , E. Bradley
1 Fondazione San Sebastiano, CREA Research and Clinical Centre,
Florence, Italy
2 Faculty of Health Sciences, University of Sydney, Brain & Mind
Centre, Centre for Disability Research and Policy, Sydney, Australia
3 Local Health Unit ASL 2, Adult Autism Spectrum Disorder Center,
Turin, Italy
4 University of Toronto, Department of Psychiatry, Toronto-Ontario,
Canada
∗ Corresponding author.
Background and aim Recent evidences of clinical overlap, familial
co-aggregation, and shared genetic alterations support a neu-
rodevelopmental deviation to represent a probable common
vulnerability factor not only for the psychiatric disorders included
in the meta-structure of neurodevelopmental disorders, but also
for other major psychiatric disorders, including schizophrenia.
The present paper reviews the literature to identify (1) positive and
negative implications of the increasing enlargement of the group of
neurodevelopmental disorders and (2) most useful clinical aspect
for re-defining diagnostic boundaries between syndromic groups.
Methods The search purpose was reached through a systematic
mapping of literature.
Results The last years’ trend to increasingly enlarge the number
of psychiatric features comprised in the autism spectrum should
be better evaluated for potential negative impact on research and
clinical resources for those autistic syndromes more reliable with
Kanner’s descriptions or associated with lower personal function-
ing profiles and different level of ID.
Crucial clinical aspects for the differentiation resulted to be age
of onset, interest towards others, main positive symptoms, and
anatomical anomalies of the central nervous system.
Conclusions While on one hand the neurodevelopmental per-
spective might contribute to a better understanding of the
multifactorial aetiopathogenetic mechanisms underlying many
psychiatric disorders and provide new intervention strategies, on
the other hand itmight determine a premature abandonment of the
traditional nosology and the appearance of very broad spectrum
conditions covering all the range of current psychopathology.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0196
One-year changes in psychiatric
disorders following bariatric surgery
E. Bianciardi ∗, D.L. Giorgio , N. Cinzia , G. Flavia , G. Paolo ,
S. Alberto
1 University of Rome Tor Vergata, Systems Medicine, Rome, Italy
2 University of Rome Tor vergata, Department of experimental
medicine and surgery, Rome, Italy
∗ Corresponding author.
Introduction Psychiatric disorders in obese patients range from
20% to 60%, with a lifetime prevalence as high as 70%. Bariatric
surgery (BS) is an effective therapy for long-term weight con-
trol and ameliorates comorbidities. After BS, psychiatric outcomes
are still a matter of controversy. Moreover, while psychosocial
pre-surgical evaluation is mandatory, post-operatively psychiatric
follow-up programs are lacking. Aim of this prospective study was
to examine changes in psychiatric symptoms and weight over 1
year of follow-up among a population of individuals submitted to
BS.
Methods One hundred forty eight participants were enrolled, 98
women and 50 men; mean age was 46 (SD = 10.7), and mean BMI
was 46 (SD = 7.7). Clinical interview and self-report instruments
were administered before and one year after BS. Depressive symp-
toms were measured using Beck Depression Inventory (BDI), Binge
Eating Disorder was measured using Binge Eating Scale (BES).
Results One year after surgery 86% of patients achieved a per-
centage excess weight loss (%EWL) ≥ 40%. Rate of psychiatric
comorbidities declined from 41% at pre-surgery to 12% at 1
year post-surgery, P= 0.01. BDI mean score declined from 12
to 8, P > 0.000. After BS, binge eating, depressive symptoms,
and age were independent and significant predictors of %EWL
(F6,523 = 79.599, P < 0.0001, adjR2 = 0.471).
Conclusions We reported an improvement of psychiatric symp-
toms through 1 year after BS. Post surgical binge eating disorder
and depression were associated with less weight loss after surgery,
adding to the literature suggesting that psychiatric disorder after
surgery, unlike pre-surgery, are related to suboptimal weight loss.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0197
Improving dual diagnosis care in
acute psychiatric inpatient settings
through education
K. Bonnie
Providence Health Care/Yale University, Psychiatry, Langley, Canada
∗ Corresponding author.
Background Patients with co-existing substance use and men-
tal disorder (dual diagnosis) have complex and challenging care
needs. Acute psychiatric care settings play a vital role in providing
services for patients with dual diagnosis as they often do not volun-
tarily seek treatment. This is significant in that recent data reveals
that 57% of the psychiatric inpatients at an inner city hospital in
Vancouver, Canada are characterized as dual diagnosis.
Purpose To develop an educational module which will equip
nurses/practitioners with the skills and knowledge required to
deliver evidence-based dual diagnosis care in acute psychiatric
settings.
Methods A survey of 74 nurses working in acute psychiatric sett-
ings was completed to identify their learning needs and challenges.
This was followed by a comprehensive review of evidence from lit-
erature to identify competencies, knowledge and skills needed to
deliver dual diagnosis care. Content for the educational modulewas
then validated by a panel of leading international experts on dual
diagnosis. Two focus groups of acute psychiatric nurses were then