European Psychiatry - Volume 41 - April 2017

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S744 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S710–S771
Results The clinical case involves a 62-year-old man, with no
psychiatric history, who begun to present depressive symp-
toms, emotional lability, aggressiveness and amnesic deficits with
4months of evolution. After realize an exhaustive clinical evalua-
tion, a cerebral MRI and LCR analysis, the results were consistent
with seronegative AI LE. The patient was treated with corticoid
therapy and presented a favorable evolution, with remission of the
symptoms.
Conclusions Even though it is a rare pathology, AI LE is an impor-
tant differential diagnosis to consider in patients with psychiatric
symptoms and it is essential to enhance the early detection and
treatment of this pathology. This condition also reinforces the role
of AI diseases in psychiatric disorders in general, an area, which
requires further investigation. With this clinical case, we expect
medical professionals to be able to recognize the importance of
this diagnosis.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
e-Poster Viewing: Psychopathology
EV1045
Behavioral disorders: Within the
limits of psychiatry or neurology?
About a case
P. De Jaime Ruiz (Resident Medical Intern) ∗,
J. Fernández Logro˜no (Psychiatrist)
Hospital Universitario Granada, Psychiatry, Granada, Spain
∗ Corresponding author.
E-mails addresses: (P. De Jaime Ruiz),
(J. Fernández Logro˜no)
It has been a clinical case of a polimorphic psychotic disorder in
a male of 26-year-old, affected by brain palsy, previously with
adequate cognitive function, undergoing remarkable confusional
fluctuations and a waking state apparently well-preserved. As pos-
sible comorbidities or triggers we could count on a tonsillitis and/or
a depressive reaction a few days before. Serious consideration
must be given to a differential diagnosis with an encephalitis but,
despite the presence of an intermittent febricula, it was rejected
by both units: internal medicine and neurology, after perform-
ing some complementary tests, albeit some more specific tests are
still pending. His psychiatric background was also checked, which
initially was orientated as a questionable bipolar disorder. At all
events, symptoms stopped progressively until, almost complete
remittance in the moment he was discharged from the hospital.
He recovered his normal functionality. The treatment given was
risperidon 2mL/day, quetiapin 50mg/8 h and baclofen 10mg/12 h.
This can be used as an example of how many difficulties we usu-
ally found to catalogue an acute disorder in first phases, even to
encompass the clinical profile within the limits of psychiatry or
neurology.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1046
The role of dissociation in patients
with a diagnosis of borderline
personality disorder and adverse
attachment experiences
D. Galletta ∗, N. Vangone , A.I. Califano , S. De Simone , V. Suarato ,
A.M. Mastrola
University of Naples Federico II, Neuroscience, Naples, Italy
∗ Corresponding author.
In literature, the link between childhood abuse stories, trauma,
unresolved attachment and psychopathological manifestations
characterized by the presence of significant dissociative symp-
toms are well documented. The treatment of this kind of clinical
pictures is very problematic because of dysfunctional relational
dynamics acted by patients. As we know, borderline personal-
ity disorder patients and those with unresolved attachment show
poor emotion regulation. About that, a very recent study found
an alteration of the neural mechanism involved in the top-down
control process of emotional distress both in BPD patients and
in those with unresolved attachment. In this context, to make
an accurate psychological assessment is essential to define and
understand the overall patient functioning and identify the most
appropriate therapeutic strategies. In this study, we have selected
22 women characterized by a diagnosis of borderline personal-
ity disorder, dissociative experiences and childhood abuse stories.
The psycho-diagnostic examination of this sample involved the use
of the following tools: Rorschach, MMPI-2, WAIS-R and drawing
tests. Consistent with the literature, the outcomes confirmed the
presence of response patterns related to trauma, abuse stories and
dissociation in both Rorschach and MMPI-2. At the same time, in a
significant portion of the sample, we have found an intact cognitive
functioning; this aspect, as showed by other authors, highlights the
adaptive function of the defensive mechanism of dissociation.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1047
Psychopathology of depersonalization
and de-realization. What is the limit
between normal and pathological?
G. Hernandez Santillan
Gina Asunta, Hernandez-Santillan, Hospital Universitario Príncipe de
Asturias, Madrid, Spain
A 21-year-old woman, distance-learning psychologist with a his-
tory of parent violence during her early childhood in the context of
her father’s alcohol poisoning, describes experiences of deperson-
alization and de-realization, of which she is aware since the age of
five years, in situations of stress or out, for example, when looking
in the mirror or even playing. She consulted to psychiatry, seven
months after his father died of lung cancer, he frequently smoked
tobacco and cannabis at home, had been diagnosed a year before
his death. The patient described increased anxiety symptoms, with
panic attacks, hypnopompic and hypnagogic hallucinations, and
increased depersonalization and de-realization phenomena. She
denies the use of psychoactive substances in addition to tobacco
and alcohol, occasionally. Likewise, the depressive symptomatol-
ogy was objectified in relation to the grief for the loss of his father.
She received treatment with SSRIs and two months later, referred
partial remission of symptoms, with persistence of dissociative
symptoms. In addition, she presents emotional instability, feel-
ings of emptiness, self-defeating ideas without structured suicide
ideation. In recent months, he has presented avoidant behaviors
and isolation with affectation in his habitual functioning. Now, in
this case: are depersonalization and de-realization normal, part of
the anxiety crisis, a sign of a high-risk mental state, or a prelude to
a serious mental illness?
Disclosure of interest The author has not supplied his/her decla-
ration of competing interest.