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S882

25th European Congress of Psychiatry / European Psychiatry 41S (2017) S847–S910

weight loss for the past month. In the days preceding his presen-

tation, he has experienced worsening irritability and rapid speech,

and has been responding to internal stimuli and displaying odd

repetitive movements of his extremities. On interview, the patient

reported non-compliance to his prescribed Lithium and Paroxetine

for the past threemonths. He also noted recently smokingmetham-

phtamine on a daily basis for the past month and intermittently

abusing cannabis, benzodiazepines and cocaine. His urine drug

screen was positive for cannabinoids and amphetamines and the

rest of his medical workup was within normal limits. On physical

exam, he exhibited involuntary writhing and twisting movements

of his extremities. An atypical antipschotic was prescribed, after

which his choreoathetotic movements resolved within 24 hours.

The purpose of this poster is to highlight the possibility of devel-

oping chorea as a result of methamphetamine use, given the rarity

of such cases, and to discuss whether the resolution of his neu-

rological symptoms were a result of antipsychotic administration

or were simply due to the natural course of methamphetamine

discontinuation during hospitalization.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.01.1780

EV1451

Psychological distress and alcohol use

among adolescents

N. Charfi

, M. Turki , N. Smaoui , M. Maalej Bouali , L. Zouari ,

N. Zouari , J. Ben Thabet , M. Maalej

Hedi Chaker University Hospital, Psychiatry “C” Department, Sfax,

Tunisia

Corresponding author.

Introduction

Anxiety and depression, as well as alcohol use are

widespread among teenagers, and constitute a huge public health

burden worldwide.

Objective

To study the link between alcohol consumption and

emotional distress (anxiety and depression) among adolescents.

Methods

We conducted a cross-sectional study in May and June

2016. The sample consisted of 314 pupils from 4 colleges and

schools in Sfax (Tunisia). Alcohol Use Disorders Test (AUDIT) was

used to evaluate alcohol dependence. Anxiety and depression levels

were evaluated using the “Hospital Anxiety and Depression Scale”

(HADS).

Results

Themean agewas 16 yearswith a sex ratio of 1.08. Among

the participants, 18.9% reported having drunk alcohol at least once

and 42.37% of them still consume. The main reasons for alcohol ini-

tiation were the search of new experiences (78%) or pleasure and

well-being (39%) and the curiosity (49.15%). According to AUDIT,

1.7% of alcohol users presented an alcohol misuse and 20% pre-

sented dependence.

The prevalence of anxiety and depression were respectively 56.1%

and 23.7%. Anxiety was correlated to alcohol experimentation

(

P

= 0.03) and non-supportive environment (

P

= 0.003). Depression

was correlated to alcohol experimentation (

P

= 0.001), AUDIT score

(

P

= 0.009), somatic histories (

P

= 0.02), physical abuse (

P

= 0.02),

non-supportive environment (

P

= 0.016) and graduating class level

(

P

= 0.005).

Conclusion

Our study highlights the close association between

alcohol consumption and emotional distress in adolescence, which

seems to be bi-directional. When attempting to reduce the risk

of alcohol consumption, we should focus a particular attention

on adolescents studying in graduating class, reinforce adolescents’

family support and prevent physical abuse.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.01.1781

EV1452

Stability of problematic gaming and

associations with problematic

gambling: A three-year follow-up

study of adolescents in the

SALVe-cohort

S. Vadlin

, C. Åslund , K.W. Nilsson

Uppsala University, Centre for Clinical Research, Västerås, Sweden

Corresponding author.

Aim

The aims of the present study was to investigate the long-

term stability of problematic gaming among adolescents, and

whether problematic gaming at wave 1 (W1) were associated with

problematic gambling at wave 2 (W2), three years later.

Methods

Data from the SALVe-Cohort, including adolescents

in Västmanland born in 1997 and 1999, at two waves were

analyzed (W1,

n

= 1868; 1035 girls, W2,

n

= 1576; 914 girls).

Adolescents self-rated the Gaming Addiction Identification Test

(GAIT), Problematic Gambling Severity Index (PGSI), and gam-

bling frequencies. Stability of gaming using Gamma correlation,

and Spearman’s rho was performed. General linear model anal-

ysis (GLM), and logistic regression analysis were performed,

adjusted for sex, age, and ethnicity using PGSI as dependent

variable, and GAIT as independent variable, for investigat-

ing associations between problematic gaming and problematic

gambling.

Results

Problematic gaming was stable over time,

= 0.810,

P

0.001, and = 0.555,

P

0.001. Furthermore, problematic gam-

ing at wave 1 increased the probability of having problematic

gambling three years later, GLM F = 3.357,

2

= 0.255,

P

0.001,

and logistic regression OR = 5.078 (95% CI: 1.388–18.575),

P

= 0.014.

Male sex was associated with higher probability of problematic

gambling.

Conclusions

The present study highlights the importance of

screening for problematic gambling among problematic gamers in

order not to overlook possible coexisting gambling problems. The

stability of problematic gaming indicates a need for development

and evaluation of treatment for problematic gaming and also for

coexisting gambling problems.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.01.1782

EV1453

ASD, SUD and gender

P.J.M. Van Wijngaarden-Cremers

Dimence, Centre for Developmental Disorders, Zwolle, The

Netherlands

Introduction

Autism and substance use disorder (SUD) is not the

co-morbidity that is commonly considered. Yet these conditions

have more commonalities than one would suspect.

Objective

We will consider the evidence for co-morbidity

between ASD and Addiction (Substance Use Disorders (SUD) and

explore the influence of gender.

Method

A pilot study of 80 admissions to an adult ASD unit will

be presented.

Results

The co-morbidity ASD and SUD in this study was very

high (65% of the inpatients). There were no gender differences in

prevalence in total but addiction to medication (32% in woman

vs. none in man) and eating disorders (24% in women vs. 9%

in man) was far more common in women whereas addiction to

drugs (13% in man vs. none in women) was far more common

in man.

Conclusions

There are clear indications that a possible co-

morbidity of substance abuse disorder should be considered in

cases of individuals with autism spectrum disorders. There are no

gender differences in prevalence of co-morbidity ASD and SUD in