European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S106–S169 S107
Disclosure of interest The author has not supplied his/her decla-
ration of competing interest.
EW0003
Do not be afraid: Novel approaches to
the treatment of anxiety disorders
L. Carvalhão Gil ∗ Lázaro , A. Ponte
Centro Hospitalar Psiquiátrico de Lisboa, Psychiatry, Lisboa, Portugal
∗ Corresponding author.
Introduction Anxiety disorders (AD) are associated with sig-
nificant morbidity and often are chronic and resistant to the
treatment. A fascinating aspect of AD is the interplay of genetic
and experiential factors. It is stablished that abnormal genes pre-
dispose to pathological anxiety states; however evidence clearly
indicates that traumatic life events and stress are also etiologically
relevant. The behavioral theories of anxiety postulates that anxiety
is a conditioned response to a specific environmental stimulus.
There may be two ways to neutralize fear conditioning either by
facilitating a process called extinction or by blocking a process
called reconsolidation.
Objectives Review novel approaches to the treatment of AD.
Aims To update on treatment for AD.
Methods A literature searchwas performed on PubMed database.
Results Cognitive behavioral therapies use exposure techniques,
in which the patient has to confront the fear-inducing stimuli in a
safe environment in order to facilitate the fear extinction. The ther-
apy is often context-specific, so one way of strengthen extinction
learning is by boostingNMDA receptor activation, eitherwith direct
acting agonists (D-cycloserine) or with indirect glycine enhancing
agents (selective glycine reuptake inhibitors). Memory reconsoli-
dation is based on the notion that memories are dynamic rather
than stable. Reactivation of a memory can return it to a labile state
from which it must be reconsolidated. Blocking reconsolidation is
a therapeutic opportunity of update and alter the memory, weak-
ening traumatic memories. Beta-blockers and opioids may disrupt
this process.
Conclusions Psychotherapy and psychopharmacology may have
a synergistic role in AD treatment.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0004
Symptom validity testing (SVT) and
social security disability claims
J. De Jonghe ∗, T. Schoemaker , D. Lam , P. Andre de la Porte
1 Noordwest Ziekenhuisgroep, Geriatric medicine/Medical
psychology, Alkmaar, Netherlands
2 Noordwest Ziekenhuisgroep, Medical psychology, Den Helder,
Netherlands
3 Slotervaart Hospital, Medical psychology, Amsterdam, Netherlands
4 DC Clinics, Verzuimdiagnostiek, Amsterdam, Netherlands
∗ Corresponding author.
Background and aims Over 50% of adult disability claimants fail
some form of SVT. While some over report psychological, affective
symptoms, others may report incredible cognitive symptoms. We
examined effects of different types of response bias on free recall
and self-reported depression.
Participants and methods This is a single site cross-sectional study
using a convenience sample (n = 224) of disability claimants in the
Netherlands. The Green Word Memory Test (GWMT) was admin-
istered to all subjects. The Amsterdam Short Term Memory Test
(AKTG), the Structured Inventory of Malingered. Symptomatology
(SIMS), and the beck depression inventory (BDI-II) were adminis-
tered in subsamples. Participant classification according to GWMT
and SIMS outcomes resulted in four groups, G+/S+, G+/S−, G−/S+
and G−/S−.
Results Average age of the participants was 46.3 years (SD 9.9),
41.5%were female, and 43%were higher educated. GWMTwas pos-
itive in 48.2% of all subjects, and 27.6% scored positive on both
GWMT and SIMS. Analysis of variance of GWMT Free recall and
Beck depression scores showed significant group differences [F(3,
123) = 33.21, P= .000] and [F(3, 106) = 25.17, P= .000] respectively.
Conclusions Non credible test performance was prevalent in this
Dutch study of disability claimants. Insufficient effort and over
reporting of psychological symptoms are associated with different
score profiles on regular tests and self-rating scales.
Disclosure of interest The author receives funding for his work as
a neuropsychologist in an expertise setting.
EW0005
Psychoemotional disorders in
pregnancy with hypertensive
complications
Z. Gardanova ∗, D. Khritinin , K. Anisimova
1 Pirogov Russian National Research Medical University, Department
of Psychotherapy, Moscow, Russia
2 Pirogov Russian National Research Medical University,
psychotherapy, Moscow, Russia
∗ Corresponding author.
Psychoemotional disorders in pregnant women represent a sig-
nificant medical and social problem as well as the effects caused
by this pathology have a profound effect on children born to
such mothers, as well as to themselves mothers during and after
pregnancy. The goal–psychological correction of psycho-emotional
states in pregnant women with hypertensive syndrome by Erick-
son hypnosis. The study was conducted on the basis of state
organization “Research Center for Obstetrics, Gynecology and Peri-
natology named after Academician VI Kulakov”. The study involved
150 pregnant women with hypertensive syndrome. Seventy-five
pregnant women with hypertensive syndrome received psycho-
logical correction method of Erickson hypnosis in an amount of 15
sessions. To assess the state of mental and emotional techniques
used depression scale Beck Anxiety Scale, Spielberger-Hanin. The
study was conducted 4 times–the first, second, and third trimesters
of three months after childbirth. When comparing the psycho-
emotional state of pregnant women with hypertensive syndrome
on the background of psychological adjustment method Erickson
hypnosis and in pregnant women with hypertensive syndrome
who did not receive psychological correction revealed a statisti-
cally significant difference. In pregnant women with hypertensive
syndrome who received psychological correction method of Erick-
son hypnosis, revealed lower levels of depression and situational
anxiety than women who did not receive psychological correc-
tion. Thus, our study proved the need for psychological correction
method of Erickson hypnosis and its effectiveness for stabilizing
the psycho-emotional state of pregnant women with hypertensive
syndrome and pre-eclampsia prevention.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0006
Comparing the effects of cognitive
behavior therapy or regular physical
exercise on sleep in the treatment of
patients with panic disorder
A. Hovland ∗, I.H. Nordhus , E. Martinsen , T. Sjøbø ,
B. Gjestad , H. Johansen , S. Pallesen