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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S106–S169


Hundred and fifty amateur and/or professional musi-

cians who regularly take part in public performances (GM) and 150

subjects from the general population (GP) completed a task of facial

emotion recognition and were assessed in terms of accuracy and

reaction time. The group ofmusicianswas subdivided between sub-

jects with and without MPA indicators. Data were analyzed using

Student’s t test (


< 0.05) within the statistical package for the social



GM were less accurate and had a longer reaction time in

the recognition of facial happiness (


< 0.001, effect size: 0.25–0.44)

compared to GP. Musicians with MPA had a still lower accuracy in

the recognition of happiness, as well as longer reaction times for

emotions as a whole (


< 0.04; effect size: 0.32–0.40) compared to

musicians without MPA.


The poorer performance of musicians in the recog-

nition of happiness suggests difficulties to recognize indicators of

social approval, which may negatively affect performance through

increased anxiety and negative thoughts that can favor the onset

of MPA.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.


A single dose of oxytocin on music

performance anxiety: Results

involving a situation of simulated


F.L. Osório

, A.E. M. Barbar , M.F. Donadon , J.A.S. Crippa

Medical School of Ribeirão Preto - São Paulo University, Neuroscience

and Behaviour, Ribeirão Preto, Brazil

Corresponding author.


Music performance anxiety (MPA) is a persistent

and distressing experience that involves apprehension linked

with musical performance in public (individual or collective).

Anxious individuals concentrate their anxiety in situations that

involve social scrutiny, favoring distorted, dysfunctional, and neg-

ative interpretations of that situation followed by experiences of

physiological symptoms associated with the exposure. The most

commonly used substances in the pharmacological management

of MPA are beta-blockers and benzodiazepines. However, these

options are not fully efficient and cause relevant side effects that

interfere mainly with performance. Therefore, investigations on

alternative substances to treat MPA are highly opportune.


To assess the acute effects of oxytocin (OT) on physi-

ological and cognitive variables during an experimental model of

simulated performance.


We assessed 12 musicians with MPA pre-treated with

intranasal OT (24 UI) or placebo in a crossover trial involving an

experimental situation of public performance. Cognitive and phys-

iological measures (heart rate, blood pressure, salivary cortisol)

were recorded before/during performance (anticipatory perfor-

mance anxiety). Statistical analyses were made using Stata Direct.


The results showed no effects of OT on physiological

symptoms (


> 0.190). In respect to anticipatory anxiety, however,

we found a tendency for OT to reduce negative cognitions asso-

ciated with music performance (


= 0.06). No side effects were

reported by musicians throughout the trial.


These tendencies, if confirmed through the expan-

sion of the sample, have important implications for the practice of

amateur and professional musicians who could benefit from inter-

ventions as the one described, possibly with a lesser impact of side


Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.


Music performance anxiety: Perceived

causes and coping strategies

F.L. Osório

1 ,

, A.B. Burin


, I.S. Nirenberg


, A.E.M. Barbar



Medical School of Ribeirão Preto, São Paulo University,

Neuroscience and Behaviour, Ribeirão Preto, Brazil


Rio de Janeiro Federal University, Music School, Rio de Janeiro, Brazil

Corresponding author.


The understanding of the causes of music perfor-

mance anxiety (MPA) and of strategies to cope with it is important

for the comprehension/management of this common condition in



To investigate the causes of MPA reported by Brazilian

musicians and the efficacy of the most commonly used strategies

to cope with it.


Two hundred and fourteen Brazilian musicians (53%

professional/musicians from orchestras, 67% male, mean age:

34.02 years, 65% with over 11 years of education, 42% of which

played string instruments) completed different self-rating scales

to assess the presence/absence of MPA.


Thirty-nine per cent of the musicians had indicators

of MPA. The most commonly reported causes were repertoire

difficulty (57%), concerns about audience response (52%), and self-

pressure (51%). The most common coping techniques included

breathing/relaxing techniques (66%) and increased practice (53%),

regarded as efficient by at least 49% of the musicians. Strategies

like seeing a doctor/psychiatrist/psychologist and taking antide-

pressant/anxiolytic medication were among the least frequently

used in the sample. Also, 18% of musicians with MPA used beta-

blockers and 6% used non-prescribed medications. Comparatively,

musicians with MPA believed that it was associated with a higher

number of conditions and regarded coping techniques as less effi-



Musicians consider internal situations to be the

most frequent causes of MPA and use different coping strate-

gies with average effectiveness. Results highlight the poor use of

well-established therapeutic resources and the occurrence of self-

medication in the sample, which together point to the need for

attention on the part of mental health professionals to this specific


Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.


Pregabalin in somatoform disorders

D. Pavicevic

1 ,

, D. Popovic


, N. Zivkovic


, G. Djokic



Clinic for Mental Disorders “Dr Laza Lazarevic”, Intensive Care Unit,

Belgrade, Serbia


General Hospital “Petrovac na Mlavi”, Psychiatric Practice and

Consultative Service, Petrovac na Mlavi, Serbia


Clinic for Mental Disorders “Dr Laza Lazarevic”, Department for

acute psychosis, Belgrade, Serbia


Clinic for Mental Disorders “Dr Laza Lazarevic”, Assistant Director,

Neurology Consultation Service, Belgrade, Serbia

Corresponding author.

Somatoform disorders (SD) are an example of the complex interac-

tion between mind and body.

To estimate the efficacy of pregabalin (PG) versus combination of

pregabalin and antidepressants in patients with SD who were pre-

viously on long-term treatment with at least three antidepressants

(SSRI, SNRI, SARIs, SNDIs, MAOI, TCAs) in an adequate therapeu-

tic dose and had a partial response on it. In this open label trial

investigators diagnosed 41 patients by standard clinical interview

as F 45.0 and F 45.4 according to ICD-10 criteria and divided them

in two groups: experimental (Pregabalin, 20 patients) and control