European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S106–S169 S115
Background Studies have shown that beliefs, attitudes and
knowledge towards bipolar disorder are influenced by country-
specific social and cultural factors. Our study aims to improve and
assess public beliefs, knowledge and attitude towards bipolar dis-
order in Pakistan.
Methods We targeted 500 population. A questionnaire was orga-
nized into four sections in order to investigate knowledge about
bipolar disorder, attitudes and beliefs, treatment options and fight-
ing stigma and help seeking attitudes.
Results Of the 500 participants, 28% people were aware of exact
definition of bipolar disorder. A widespread belief (85%) was that
people suffering from bipolar disorder should avoid talking and
telling about their illness. According to 50% respondents peo-
ple experiencing bipolar disorder “are dangerous to others”, 68%
population viewed it as a result of black magic. Sixty-five per
cent thought that the best way to recover from bipolar disor-
der consisted in seeking help from Psychiatrist. Twenty per cent
thought to take help from religious people and shrines. Most of
people seemed convinced that drugs are addictive (70%) and may
cause serious side effects (80%).
Conclusions Mental health illness including bipolar disorder can
be improved by the positive influence of education, employment
availability, respect, social support, rehabilitative services, justice
and equity. Lack of education, stigmatization, and cultural norms
are the leading barriers towards.
Disclosure of interest The author has not supplied his/her decla-
ration of competing interest.
EW0028
Association between HbA1c and
number of episodes in individuals
with bipolar disorder
F. Fellendorf
Medical University of Graz, Psychiatry, Graz, Austria
Introduction Bipolar disorder (BD) is associatedwith an impaired
glucosemetabolism(IGM) leading todiabetesmellitus Type II (DM).
DM influences the medical state of BD individuals and leads to
increased mortality. However, there is evidence that IGM is associ-
ated with psychiatric symptoms, as well.
Aim The study aimed to investigate the association between IGM
and number of episodes and their ratio in individuals with BD,
separated for gender.
Methods HbA1c levels from fasting blood were measured of 162
individuals (46% females) with BD. Furthermore, clinical param-
eters e.g. number of depressive and (hypo)manic episodes were
gathered.
Results After adjustment for illness duration and BMI there was a
positive correlation in male individuals between HbA1c and num-
ber of depressive (M= 13.86, SD = 14.67; r= .308, P < 0.05) as well
as (hypo)manic episodes (M= 17.23, SD = 24.24; r = 0.263, P < 0.05).
There was no association in females as well as between HbA1c
levels and ratio of episodes.
Conclusion Associations between HbA1c and number of episodes
in male individuals with BD were found. As there are correlations
between IGM and somatic co-morbidities as well as the course of
illness the treatment of glucose metabolism is important in BD.
However, number of episodes might have an impact on the glucose
metabolism due to inflammation processes, but further investiga-
tions have to focus on the direction of the found correlation. As
gender differences are known in different pathways, they should
be considered in research, diagnosis and therapy.
Disclosure of interest The author has not supplied his/her decla-
ration of competing interest.
EW0029
Gender difference among admitted
patients with bipolar disorder in a
psychiatric service during a three-year
period
M. Fernandes∗, D. Mota , A. Olivera , J. Ribeiro , S. Silva , V. Santos ,
N. Madeira , P. Celsa , Z. Santos
Centro Hospitalar e Universitário de Coimbra, Centro de
Responsabilidade Integrada em Psiquiatria e Saúde Mental, Coimbra,
Portugal
∗ Corresponding author.
Introduction Gender differences in bipolar disorder are becoming
apparent, but have been less studied compared with major depres-
sion. The presentation, clinical features, course and evolution of
bipolar disorder differ between men and women. Research data on
these differences will help determine whether gender is important
in influencing illness variables.
Objectives Determinewhether men andwomenwith bipolar dis-
order have statistical significant differences in socio-demographic
and clinical data.
Methods Charts of all patients with a diagnosis of bipolar disor-
der admitted in the Coimbra Hospital and Universitary Center over
a three-year period (between 2013 and 2015) were reviewed to
gather data on socio-demographic, clinical and psychopathological
variables to assess differences across genders. Statistical analysis of
data with “SPSS21”.
Results During a three-year period, 189 patients were admit-
ted with bipolar disorder, the majority were female patients, with
ages between 21 and 84 years old. The authors will analyse if
there is any statistical significant difference between gender in
the rate of bipolar I or II diagnoses, age at onset, symptom pre-
sentation, delay in diagnoses, number of depressive, or manic
episodes, hospitalisations, involuntarily admissions, number of
suicide attempts, co-morbidity rates, negative life events, fam-
ily history and treatment options. Sociodemograpic characteristics
will also be analysed.
Conclusion Gender differences in bipolar disorder is a controver-
sial issue in the literature. The importance of gender on the course
and outcome in bipolar disorder has been widely acknowledged.
The limited data suggest that the prevalence is similar between
sexes but that the course of illness may be different.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0030
Epidemiological and clinical variables
related with the predominant polarity
on bipolar disorder: A systematic
review
J. García-Jiménez ∗, A. Porras-Segovia , J.M. Gota-Garcés ,
J.E. Mu˜noz-Negro , L. Gutiérrez-Rojas
1 Psychiatrist, Acute Psychiatric Hospitalization Unit. Mental Health
Clinical Management Unit, Granada Hospital Complex, Granada,
Spain
2 Third year resident in psychiatry, Acute Psychiatric Hospitalization
Unit, Mental Health Clinical Management Unit. Granada Hospital
Complex, Granada, Spain
3 First year resident in psychiatry, Acute Psychiatric Hospitalization
Unit. Mental Health Clinical Management Unit, Granada Hospital
Complex, Granada, Spain
∗ Corresponding author.
Introduction Type I and type II classification of bipolar disorder
(BD) may not provide useful information to the clinician regarding
epidemiological and clinical correlates.