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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S238–S302



Connection between coping strategies

and quality of life in outpatient with

depression – cross-sectional study

M. Holubova

1 , 2 ,

, J. Prasko



University of Palacky Olomouc, Department of Psychiatry, Olomouc,

Czech Republic


Regional Hospital Liberec, Department of Psychiatry, Liberec, Czech


Corresponding author.


The quality of life is a multidimensional phe-

nomenon which represents all aspects of patient’s well-being and

various areas of the patient’s life. Specific coping strategies may be

connected with the quality of life and also with the severity of the

disorder. The objective of this study was to explore the relationship

between the coping strategies and quality of life in outpatients with

depressive disorder.


Eighty-two outpatients, who met ICD-10 criteria for

depressive disorders, were enrolled in the cross-sectional study.

Data on sociodemographic and clinical variables were recorded.

Individuals with depression filled out the standardized measures:

The Stress Coping Style Questionnaire (SVF-78), The Quality of Life

Satisfaction and Enjoyment Questionnaire (Q-LES-Q), and The Clin-

ical Global Impression (CGI).


The patients overuse negative coping strategies, espe-

cially, escape tendency and resignation. Using of positive coping is

in average level (the strategy Positive self-instruction is little used).

Coping strategies are significantly associated with quality of life.

Higher using of positive coping has a positive association with QoL.

The main factors related to QoL are the subjective severity of the

disorder, employment and positive coping strategies according to

regression analysis.


This study revealed the connection between coping

strategies and quality of life in patients with depressive disorders.

Strengthening the use of positive coping strategies may have a pos-

itive effect on the quality of life, mental conditions and treatment

of patients with depression.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.


Features of formation and system of

psychoprophylaxis of suicidal

behavior in young patients with


H. Kozhyna

, V. Mykhaylov , K. Zelenskay

Kharkiv National Medical University, Psychiatry, Narcology and

medical psychology, Kharkiv, Ukraine

Corresponding author.

The work covers the study of the formation of suicidal behavior in

young adults with depressive disorders and developing of patho-

genetic based system of its prevention. There were clinical and

psychopathological signs of depressive disorders in young patients

analyzed. Anxiety, asthenia, asthenic-apathetic and melancholy

variants of depressive disorders in young patients with suicidal

behavior were highlighted. In this study, there were the mark-

ers of suicide risk for young patients with depressive disorders

determined: high suicide risk, low death self-consciousness, high

anhedonia level, clinical manifestations of anxiety and depression

by the hospital anxiety and depression scale, severe anxiety and

depression by the Hamilton anxiety rating scale, major depres-

sive episode by the Montgomery-Asberg depression rating scale.

It has been proved that in observed young patients with depressive

disorders with suicide behavior increased concentrations of sero-

tonin, cortisol, noradrenaline and decreased levels of adrenaline

and melatonine in plasma were observed. These changes were

determined as neurohormonal background for depletion of adap-

tation resource in stress situations. There were approaches to

differentiated prevention of suicidal behavior in depressive dis-

orders in young people validated that include pharmacotherapy

(selective SSRI, melatonin, serotonin and norepinephrine), psy-

chotherapy and psychoeducation. Psychotherapeutic complexin

patients with depressive episode must include personality-

oriented psychotherapy, cognitive behavioral therapy, family

therapy and autogenous training; in disorders of adaptation – ratio-

nal psychotherapy, cognitive-behavioral analytic psychotherapy,

family therapy, autogenic training. Psychoeducation should be

carried out using information modules, training a positive self-

image, improved compliance; formation of communication skills,

problem solving, interpersonal interaction and problem-oriented


Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.


Case report: Three years of refractory

atypical depression successfully

treated with“old school”

moclobemide (maoi-r)

S. Latorre

1 ,

, I. Moreno


, M.J. Gordillo



Àrea de Salut d’Eivissa i Formentera, Communitary Mental Health

Team, Eivissa, Spain


Àrea de Salut d’Eivissa i Formentera, Psychiatry, Eivissa, Spain

Corresponding author.


Atypical depression is linked to bipolarity and

specific response to mono amino oxidase inhibitors (MAOI), treat-

ments not commonly used due to their complex handling. We

describe a successfully treated case.


Clinical description. Depression severity is assessed

with Montgomery Asberg depression rating scale (MADRS).

Clinical case

Female, 54-year-old. Major depression, since

2011, refractory to venlafaxine/aripiprazol and escitalopram

20mg/day. Manic episode with psychotic symptoms after poten-

tiation with duloxetine. Diagnose of schizoaffective disorder

was made, treated with aripiprazol 10mg/day, with established

chronical depressive symptoms, despite addition of valproate

and venlafaxine, and partial response to pramipexole up to


– Decision of cleaning up aripiprazol during 8 days and switch

to moclobemide monotherapy was made due to atypical fea-

tures. Baseline MADRS: 31. At week 2, there is change in

mood, expression, psychomotor features and speech formal and

content alterations. At week 4, activity increases, and biory-

thms normalize. At week 8 (with 600mg/day increased dose),

full response is obtained, including drive, and anxiety, with


– After one year of treatment, she has kept stability with no manic

or psychotic symptoms emergence. Reduction in dose are linked to

depression relapses. She still struggles with psychosocial recovery.

– Tolerance has been good in allmoment, except for headache crisis,

not linked to high blood pressure or diet.


MAOI still has a role in affective disorders treat-

ment, given its effectiveness, uniquemechanismof action and good

tolerability. Targeted psychopharmacological and phenomenology

knowledge can be the key to a recovery.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.