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S260

25th European Congress of Psychiatry / European Psychiatry 41S (2017) S238–S302

TARA for Borderline Personality Disorder TARA4BPD, Exec Director,

NYC, USA

Undiagnosed and untreated people with Borderline Personality

Disorder (BPD) create a public health drain on mental health

treatment. BPD underlies major public health problems including

high incidence of substance abuse, alcoholism, domestic vio-

lence, impulse control disorders, incarceration, high utilization of

emergency rooms and inpatient hospitalizations. Although BPD

has a prevalence rate between 2–5.9%, it generally goes mis-

diagnosed, undiagnosed, stigmatized and mistreated. Amongst

American veterans who are suicide attempters and completers, a

recent study found 94% meet criteria for BPD. There is rampant

professional stigma exists against BPD patients, seen as patients to

be “avoided”, “treatment refractory,” “untreatable” and a “liability”

due to increased risk of self-injurious and suicidal behavior. This is

a contributing factor to misdiagnosis that is the usual experience

for BPD patients, resulting in wasted years, hopelessness, chaos,

family crises, and severe personal and economic consequences for

patients and families. The need for assessing with validated diag-

nostic instruments to rule out or diagnose BPD, Bipolar Disorder,

ADHD, substance abuse and other co-morbid diagnoses as well as

the need to diagnosis children and adolescents at the time symp-

toms first appear will be discussed. Presentation of the shockingly

few studies on BPD versus Bipolar will be presented and the conse-

quences of failing to diagnose will be highlighted. Findings from an

on-line survey from TARA4BPD, an American education and advo-

cacy organization, will demonstrate the need for clinical education

in evidence based BPD treatments, training, and supervision as well

as patient and family psycho-education so as to improve outcome

will be presented.

Disclosure of interest

The author has not supplied his/her decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.02.065

EW0452

Personality disorders and

temperament traits in patients with

breast disease: Preliminary results

V. Prisco

1 ,

, T. Iannaccone

1

, G. Di Grezia

2

1

University of Naples SUN, Department of Psychiatry, Naples, Italy

2

University of Naples SUN, Department of Radiology, Naples, Italy

Corresponding author.

Aim of the study was to identify individual characteristics in

patients with a benign or malignant breast disease diagnosis.

The role of specific personality traits has been considered in the

assessment of temperament and character as a predictor of a

certain psychopathological state in patients with breast disease

diagnosis. Participants were interviewed using a structured clin-

ical test (SCID-II, version 2.0) disorders, and the Italian version

of Akiskal’s semi-structured clinical interview for temperamental

profiles (TEMPS-I) after clinical breast exams and ultrasonography.

All patients presented different personality disorders and hetero-

geneity in temperamental profiles. Of 29 patients with benign

breast disease diagnosis, twelve presented histrionic, seven narcis-

sistic, five dependent, four obsessive, two borderline, one antisocial

and one paranoid personality disorder. The histrionic-narcissistic

disorder is associatedwith benign breast disease. The three patients

with malignant diagnosis presented the same temperamental pro-

file: depressive temperamentwas associatedwithmalignant breast

disease diagnosis. According to recent literature personality dis-

orders cannot influence breast cancer or its prognosis. However,

a psychological consultation represent a very important step to

pre-dispose specific interventions, treating psychiatric reactive

co-morbidities. The study shows the relevance of psychiatric coun-

selling in breast units in the diagnostic cluster detection. Future

purpose is to extend the sample and to add a follow-up evaluation.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.02.066

EW0453

Hyperprolactinemia phenomenon in

neurotic and personality disorders

and changes in prolactin level after

the psychotherapy

K. Rutkowski

, E. Dembinska , J. Sobanski , K. Cyranka ,

A. Citkowska-Kisielewska , M. Mielimaka

Jagiellonian University Medical College, Department. of

Psychotherapy, Krakow, Poland

Corresponding author.

Introduction

Hyperprolactinemia is a common endocrinological

disorder. Some data suggest that psychological factors (e.g. person-

ality traits) may play a role in hyperprolactinemia genesis.

Objectives

Increased prolactin level (PRL) is described as clinical

observations in some patients, usually with a diagnosis of border-

line personality disorder. In the international literature there is lack

of broader description and information of clinical implications of

this phenomenon.

Aim

The aim of the study is to evaluate the prevalence of hyper-

prolactinemia in patients with diagnoses F40-F69 according to

ICD-10 and an evaluation of the changes in PRL after psychotherapy.

Methods

The study population comprised 64 patients, mainly

females (73%), with primary diagnosis of neurotic or personality

disorder. Prolactin level was measured during the first and last

week of the psychotherapy. Between the measurements patients

underwent intensive short-term (12 weeks) group psychotherapy

in a day hospital for neurotic and behavioural disorders.

Results

Hyperprolactinemia was found in 41% of males and 42.4%

of females in the study group. After psychotherapy significant

reduction in prolactin level was observed in 80% of woman with

hyperprolactinemia.

Conclusions

Hyperprolactinemia is observed in almost 40% of

patients with neurotic and personality disorders. Psychodynamic

psychotherapy can be a significant factor improving PRL level

in patients with neurotic and personality disorders, specifically

women.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.02.067

e-Poster Walk: Psychopathology and

Psychotherapy

EW0454

DBT for co-morbid borderline

personality disorder and substance

use disorder without drug

replacement in Egyptian outpatient

settings: A non-randomized trial

A. Abdelkarim

1 ,

, T. Molokhia

1

, A. Rady

1

, A. Ivanoff

2

1

Alexandria Faculty of Medicine, Neuropsychiatry, Alexandria, Egypt

2

Columbia University, School of Social Work, New York, USA

Corresponding author.

Background

Dialectical behavior therapy has demonstrated

effectiveness for patients suffering from co-morbid borderline per-

sonality and substance use disorder. The current study tries to