European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S521–S582 S555
Results patient had selective/restrictive eating behaviours, daily
purges and occasional binges for last five years. At age 14
she was diagnosed with ADHD by impulsivity/aggressiveness
and poor school performance, but she did not take drugs and
left medical consultations. She came to our specific unit of
EDs in november-2015. Her BMI was 24.88 kg/m2. We initiated
CBT and atomoxetine (80mg/day). In this first year of treat-
ment binges and purges have disappeared and exposure to new
foods and body image have improved partially. We found clear
improvement in mood, motivation and attention/concentration
in relation with introduction of atomoxetine. These facts have
positive impact on the clinical evolution. Her current BMI is
26.90 kg/m2.
Conclusions Identify comorbid ADHD to assess the use of specific
drugs for this disorder could be beneficial in the treatment and
prognosis of EDs. However, more studies are needed to determine
effectivenes, particularly of non-stimulant drugs.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0463
Theory of mind in binge eating
disorder: an exploratory study
A. Legnani ∗, R.M. Martoni , C. Brombin , F. Cugnata ,
R. Porta , R. de Filippis , S. Erzegovesi , M. Caputi
1 Vita-Salute San Raffaele University, Faculty of Psychology, Milan,
Italy
2 IRCCS San Raffaele, Department of Clinical Neurosciences, Milan,
Italy
3 Vita-Salute San Raffaele University, University Statistical Center for
Biomedical Sciences, Milan, Italy
∗ Corresponding author.
Introduction to date, studies on the relationship between Theory
of Mind (ToM) and eating disorders (ED) have never considered
binge eating disorder (BED).
Aims a) to assess ToM abilities in a sample of patients suffering
from BED comparing them with healthy controls; b) to evaluate
the influence of several variables (demographic, clinical and neu-
ropsychological dimensions, attachment styles, traumatic events,
comorbid Axis I and II disorders) on ToM abilities.
Methods we assessed ToM in a sample of 20 BED patients and 22
women from the general population using the Reading the Mind in
the Eyes Test (RMET) and the Faux Pas Test (FPT).
Results regarding the first aim, the comparison between groups
showed that the clinical group scored significantly lower than
the control group on the RMET as well as on FPT. Regarding
the second aim, two different multiple regression models were
performed: one for the RMET and one for the FPT. Both of
them led to significant results. When modeling RMET score, it
emerged that age and Binge Eating Scale significantly reduce the
score, while vocabulary and drive for thinness have a positive
effect (r2 = 0.62). When modeling FPT score, we found that cen-
tral coherence and binge eating significantly reduce the total score
(r2 = 0.33).
Conclusions our study begins to shed light on the relationship
between ToM and BED; in particular, it suggests that BED patients
have lower mentalization skills than healthy controls and ToMabil-
ities are partially influenced by clinical variables related to eating
pathology.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0464
Some stay the same: Personality
change after treatment for eating
disorder
J. Levallius ∗, W. Mu , C. Norring , D. Clinton , B. Roberts
1 Karolinska Institute, Clinical Neuroscience, Stockholm, Sweden
2 University of Illinois, Psychology, Urbana-Champaign, USA
∗ Corresponding author.
Introduction Strong evidence establishes a close relationship
between personality traits and mental illness; where personality
can be said to influences the likelihood, severity and longevity of
a mental disorder. Personality is usually seen as fixed, yet there
is a growing body of evidence for the changeability of person-
ality, though this has rarely been studied in relation to mental
disorders.
Objective To study the longitudinal interplay between person-
ality and eating disorders (EDs), particularly the associations
between personality, recovery and treatment modality.
Aims To investigate changes in the five domains and thirty
lower-level facets of personality in non-underweight EDs, and its
associations to intervention and outcome.
Methods Two hundred and nine adults with EDs enrolled either
in a four-month multimodal psychodynamic group-therapy (DAY)
or four-six month internet-based supported cognitive behavioural
therapy (iCBT). ED diagnosis and personality (by the five-factor
model) were assessed at baseline, termination and 6-month follow
up. Structural equationmodelingwas used to analyze domain-level
development, and reliable change (RCI) for facet-level develop-
ment.
Results Remission rate at end of treatment was 71% in DAY
and 55% in iCBT. Over time, Neuroticism decreased significantly
while Extraversion, Openness and Conscientiousness increased
(P < 0.01). Treatment and outcome had little influence on domain-
level change. At the facet-level, 28% of patients reliably changed in
any given facet, and there were several differences in pattern based
on treatment and outcome.
Conclusions This study lends support for the possibility of per-
sonality change and its relevance for recovery from EDs.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0465
Run for it: Compulsive exercise in
adolescents with eating disorders – a
nationwide longitudinal study
J. Levallius ∗, C. Collin , A. Birgegård
Karolinska Institute, Clinical Neuroscience, Stockholm, Sweden
∗ Corresponding author.
Introduction Rigorous exercise to control weight and/or shape
and to avoid negative affect has been proposed as significant in the
etiology, development and maintenance of eating disorders (EDs),
resulting in more severe and enduring pathology. However, few
studies have investigated compulsive exercise (CE) among adoles-
cents with EDs.
Objective To study the longitudinal relationship between EDs and
CE in adolescents.
Aims to investigate if adolescent ED patients show a similar
relation between EDs and CE as previous research has found in
adults.
Methods A total of 3116 girls and 139 boys from a nationwide
clinical EDs database were investigated on CE prevalence and
frequency in relation to ED diagnosis, psychiatric symptoms, asso-
ciated features and outcome. Denial of illness in self-ratings was
adjusted for.