European Psychiatry - Volume 41 - April 2017

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S804 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S772–S846
EV1224
Characteristics and duration of
untreated illness in correlation with
insight level of first time diagnosed
schizophrenia patients in rural region
of Latvia
L. Berze ∗, K. Pavlovs , K. Slikova , V. Bodins , I. Samule ,
N. Kurakina , I. Smonins , E. Rancans
1 Rigas Stradins University, Department of Psychiatry and Addiction
disorders, Riga, Latvia
2 Daugavpils Psychoneurological Hospital, Department of acute
psychosis, Daugavpils, Latvia
3 Riga Stradins University, Department of Psychiatry and Addiction
disorders, Riga, Latvia
4 Daugavpils Psychoneurological Hospital, Department of first time
psychosis, Daugavpils, Latvia
5 Daugavpils Psychoneurological Hospital, Department of differential
diagnosis in psychiatry, Daugavpils, Latvia
∗ Corresponding author.
Introduction Improved insight level among schizophrenia
patients is predictive for better illness prognosis.
Objective Explore factors connected to insight.
Aim Evaluate the insight level and clinical characteristics of first
time hospitalized schizophrenia spectrum patients.
Methods All consecutive first time hospitalized schizophre-
nia spectrum patients in a psychiatric hospital from
01.01.2016–26.09.2016. Patients were interviewed upon hos-
pitalization and at the discharge with Scale for the assessment
of positive symptoms (SAPS) and negative symptoms (SANS),
Schedule of assessment of insight-extended (SAI-E), The Calgary
depression scale for schizophrenia (C-sch), sociodemographic
and clinical data were collected. All participants signed written
informed consent and the study was approved by the Riga Stradins
University Ethics committee.
Results From 45 first episode patients, 38 met the inclusion
criteria. Mean age was 37.66 years (SD: 11.48 years), the aver-
age duration of untreated illness (DUI) was 40.5 months (SD: 57.35
months). Psychopathologic symptoms and insight levels evaluated
in scores in the 1st and 2nd interviews were as follows: SAPS 69.11
(SD: 20.78) and 33.61 (SD: 18.04), SANS 63.21 (SD: 25.30) and 40.95
(SD: 24.47), SAI-E 15.50 and 27.24 (SD: 13.24), P < 0.001, C-sch 8.50
(SD: 5.31) and 4.27 (SD: 2.86), P < 0.05. There was no statistically
significant correlation between DUI and insight level. A higher level
of insight at hospitalization correlatedwith higher levels of depres-
sion: r = 0.569, P < 0.001.
Conclusions We noticed a tendency that lower insight levels
might correlate with longer periods of untreated illness. We found
that higher insight levels correlated with higher symptoms of
depression.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1225
A gender approach in prodromes of
psychosis
C.M. Calahorro ∗, M. Guerrero Jiménez , B. Girala Serrano
1 Hospital Universitario San Cecilio, Unidad de Salud Mental,
Granada, Spain
2 Santa Ana Hospital, Psychiatry, Granada, Spain
∗ Corresponding author.
Background Only 21% of patients included in the South of
Granada’s First Episodes Program in the year 2014 were women.
Studies do not use to focus on sex differences at first-episode
samples and it can be masking some relevant variables in this pop-
ulation.
Aims In this exploratory study, we aim to focus on gynaecological
consultations during the period of untreated psychosis (DUP) at
first episodes of psychosis in women.
Methods A retrospective clinical-cases review of medical his-
tories was made searching for sociodemographic variables,
consultations during DUP and psychotic prodromal outcomes.
Results The average age of the sample was 23 years. The aver-
age of DUP was one to three months. Sixty percent of referees to
mental health services were fromprimary care and 20% fromemer-
gency services. The main symptom was persecutory or prejudice
delusions. Thirty-six percent of them were related to sexuality or
pregnancy. In most cases, the demands were not bizarre. When a
wide history was made and they were properly explored, a delu-
sional theme was appreciated and the reason for consultation was
not justified. Eg. Postcoital pill order for not taking precautions,
in a telepathic relationship. Forty percent of claims were made in
primary care. Half of them were assessed by a gynecologyst. Sixty
percent were treated in the emergency room.
Conclusions We conclude that these data are relevant for special-
ists. Both for efficient resourcemanagement and for early detection
of incipient psychosis. Gynecological abnormal demands are com-
mon in consultations to health services for specific malaise during
the period of untreated psychosis.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV1226
Paliperidone palmitate: Experience in
a community mental health unit
L. Carrión Expósito (Psychiatrist) ∗,
G.M. Chauca Chauca (Psychiatrist) ,
E.L. Guadalupe (Psychiatrist)
1 , UGC-Salud Mental Hospital Infanta Margarita, Córdoba, Spain
2 USMC Cáceres, Hospital Nuestra Se˜nora de la Monta˜na, Cáceres-
Spain, Córdoba, Spain
∗ Corresponding author.
Introduction There are many jobs that offer advantages of treat-
ment with long-acting injectable in psychosis.
Objective To know the changes in the different variables after the
start of paliperidone palmitate (PP).
Material and method We performed a descriptive and retrospec-
tive study. Were evaluated patients who received maintenance
therapy with PP during 48 months.
Results The sample was composed of 29 patients: 72.4% men and
27.6%women. Average age of 46.21 years. In ow
data obtained in relation to compliance with treatment, relapse,
maintenance dose, number of admissions and visits to emergency
departments respectively.
Conclusions The administration of PP is associated with a higher
level of compliance with treatment. The patients presented a lower
number of relapses, hospitalizations and visits to the emergency
room. The maintenance dose more used is 150mg.