European Psychiatry - Volume 41

S808

25th European Congress of Psychiatry / European Psychiatry 41S (2017) S772–S846

Method

Overall, 35 healthy participants and 43 patients with

psychosis from San Agustín Hospital (Linares, Spain) participed in

the study. Participants were asked to write with a pen on a white

paper (see patterns in the

In order to analyze the het-

erogeneity of handwriting pattterns, we employed lacunarity, a

nonlinear measure previously used in the analysis of biomedical

images. Lacunarity measures the distribution of gap sizes in a geo-

metrical space. A large value implies large gaps and clumping of

points, whereas a small value suggests a uniform distribution with

shorter gaps.

Results

Lacunarity was significantly higher in handwritten pat-

terns from patients than in controls. In addition, we found a higher

heterogeneity in patients with motor symptoms in comparison

with patients without motor symptoms.

Conclusions

Our results suggest that analysis of handwritten

patterns can be a valuablemethod in the evaluation of motor symp-

toms.

Fig. 1

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.