European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S69–S105 S85
Methods Participants underwent clinical interviews for BS,
psychosocial functioning and current mental disorder on the tele-
phone.
Results BS were reported by 18% of participants, mainly cogni-
tive BS (15%). Age seemed to affect perceptive and cognitive BS
differently, indicating an age threshold for perceptive BS in late ado-
lescence (around age 18) and for cognitive BS in young adulthood
(early twenties) – with higher prevalence, but a lesser associa-
tion with functional deficits and the presence of mental disorder
in the below-threshold groups. Thereby, effects of the interaction
between age and BS on functioning and mental disorder were com-
monly stronger than individual effects of age and BS.
Conclusion Differential age effects of perceptual and cognitive BS
seem to follow normal brain maturation processes, in which they
might occur as infrequent and temporary nonpathological distur-
bances. Their persistence or occurrence after the conclusion ofmain
brain maturation processes, however, might signify aberrant mat-
uration processes. Thus, BS might provide important insight into
the pathogenesis of psychosis and into potential neuroprotective
targets.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
O046
Risk factors for suicide attempt: A
retrospective study
L. Castaldo ∗, L. Mazzone , G. Serra , S. Vicari
Pediatric Hospital Bambino Gesù, Department of Neuroscience,
Roma, Italy
∗ Corresponding author.
Introduction Suicide is a leading cause of death among adoles-
cents.
Objectives To investigate suicidal behaviors among Italian ado-
lescents.
Aims To assess the rates of suicidal ideation (SI) and suicide
attempts (SA) and the associated risk factors in patients admit-
ted to emergency department (ED) of the Bambino Gesù Children’s
Hospital.
Methods Retrospective study based on data of patients admitted
to the ED from 1 January 2011 to 30 May 2016 who required a
neuropsychiatric (NPI) consultation. We analyzed:
– outcome of the NPI consultation (hospitalization or discharge);
– risk factors for SA and SI;
– methods employed for SA.
Results The number of NPI consultations for SI and SA increased
from6.45% in 2011 to 13.3% in 2015. More than 90% of consultations
recommended hospitalization in the psychiatric unit (137 patient
[66% female]; mean age of 15.5 ± 1.6 years) with average length
of stay of 13.64 ±10.63 days. Risk factors for SI and SA were non-
suicidal self-injury, family conflicts and previous suicide attempts.
Subjects evaluated for a SA reported a significantly higher fre-
quency of family history of mood disorder ( 2 = 5.94; P = 0.02) and
a comorbid substance abuse ( 2 = 4.49; P = 0.03) when compared
with SI group. The method most frequently used to attempt suicide
was ingestion of medications (52.83%).
Conclusions There was an increasing demand of NPI consultation
of SA and SI in the last years. A family history of mood disorder and
a history of substance abuse are risk factors able to differentiate
between SI and SA.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
Oral communications: E-mental health; bipolar
disorders; child and adolescent psychiatry; eating
disorders; intellectual disability and women,
gender and mental health
O047
A mediation analysis of childhood
maltreatment and suicidal behavior
among patients with depressive or
bipolar disorders
K. Aaltonen ∗, T. Rosenström , I. Baryshnikov , B. Karpov ,
T. Melartin äätänen Heikkinen Koivisto
K. Suominen Joffe sometsä
1 University of Helsinki and Helsinki University Hospital, Department
of Psychiatry, Helsinki, Finland
2 National Institute of Health and Welfare, Department of Health-
Mental Health Unit, Helsinki, Finland
3 University of Helsinki, Institute of Behavioural Sciences, Helsinki,
Finland
4 City of Helsinki, Department of Social Services and Health Care,
Helsinki, Finland
∗ Corresponding author.
Introduction Substantial evidence supports association between
childhoodmaltreatment and suicidal behaviour, however, a limited
number of studies have examined psychological mechanisms
mediating the relationship among patients with mood disorders.
Objective To investigate directly the potential intermediat-
ing mechanisms between childhood maltreatment and suicidal
behaviour among patients with mood disorders.
Aims We examine by formal mediation analyses, if:
– the effect of childhood maltreatment on suicidal behaviour is
mediated through borderline personality disorder traits;
– themediation effect differs between lifetime suicidal ideation and
lifetime suicide attempts.
Methods Depressive disorder and bipolar disorder (ICD-10-DCR)
patients (n = 287) from the Helsinki university psychiatric con-
sortium (HUPC) Study were surveyed on self-reported childhood
experiences, current depressive symptoms, borderline personality
disorder traits and lifetime suicidal behaviour. Psychiatric records
served to complement the information on suicide attempts.
Results The influence of childhood maltreatment on lifetime sui-
cidal ideation and lifetime suicide attempts showed comparable
total effects. In formal mediation analyses, borderline personality
disorder traitsmediated all of the total effect of childhoodmaltreat-
ment on lifetime suicide attempts, but only 21% of the total effect
on lifetime suicide ideation. The mediation effect was stronger for
lifetime suicide attempts compared to ideation (P = 0.002) and inde-
pendent of current depressive symptoms.
Conclusions The mechanisms of the effect of childhood mal-
treatment on suicidal ideation and attempts may diverge among
psychiatric patients with mood disorders. Borderline personality
disorder traits may contribute to these mechanisms, although the
influence appears considerably stronger for suicide attempts than
for suicide ideation.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.