European Psychiatry - Volume 41 - April 2017

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S284 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S238–S302
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0522
Burnout in medical residents:
Prevalence and risk factors
I. Feki entati allemi Bahloul Zalila
S. Kammoun asmoudi ∗
1 University Hospital Hédi Chaker, psychiatry, Sfax, Tunisia
2 University Hospital Hédi Chaker, pneumology, Sfax, Tunisia
∗ Corresponding author.
Background Burnout is a state of mental and physical exhaustion
related to work. It is manifested in a variety of professions and is
prevalent in contexts in which health professionals are required to
interact directly with the public.
Objectives To estimate the burnout syndrome (BOS) prevalence
and to identify its associated factors among medical residents.
Methods A descriptive and analytic study conducted during a
period from 2012 until 2014, including 184 residents exerting
at the two university hospitals of Sfax, Tunisia. Data collection
was conducted using an anonymous self-questionnaire, including
demographic items and working conditions items. Maslach Burn-
out Inventory (MBI) was used to assess BOS.
Results The average age was 25.14 ± 1.47 years. The sex-ratio
was 0.65. The majority (154 residents) was single. Over than half
(58.2%) of medical residents endure a high emotional exhaustion,
62.5% a high depersonalisation and 12.5% a low personal accom-
plishment. About eighty percent (79.3%) of them were in burn out
with 37% at intermediate and 11.3% at a severe degree. No statis-
tical association was found between the personal characteristics
and BOS. Whereas, several factors related to employment status
were correlatedwith the presence of BOS such us: number of work-
ing hours > 30 h/week, a number of free weekends < 2/month and a
number of days off ≤ 30 days/year. In addition, we found that psy-
chotropic and alcohol consumption were significantly associated
to BOS with respectively P = 0.050 and P = 0.002.
Conclusion Burnout is a worrying reality among young doctors.
Individual as well as organizational interventions should be tar-
geted to prevention.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0523
Eating disorders in schizophrenia
R. Sallemi , S. Hentati , I. Feki , J. Masmoudi ∗,
M. Moala
University hospital Hédi Chaker, psychiatry, Sfax, Tunisia
∗ Corresponding author.
Background Due to their frequency and negative impact on qual-
ity of life, eating disorders in schizophrenia need to be considered
and highlighting.
Objective To identify the risk of eating disorders (ED) and its cor-
relates among mental patients.
Methods It was a descriptive and analytic study. It included 53
inpatients with DSM-5 diagnoses of schizophrenia or schizoaffec-
tive disorder, followed in the department of Psychiatry at the Hedi
Chaker University Hospital of Sfax in Tunisia, during the three
months of August, September and October 2016. Data collections
were conducted using questionnaire exploring sociodemographic
and medical data. The SCOFF (sick, control, one, fat, food) Question-
naire was used to screen ED. A total score of ≥ 2 was used as a cutoff
point to select persons at risk of ED.
Results The average age of our patients was 30.47 ± 9.5 years old.
The majority of our patients was male (71.7%) and single (71%). The
mean of extra Body mass was 27.9. The mean duration of disease
was 9.9 ±8.1 years and patients were mostly (54%) in atypical neu-
roleptics. According to the SCOFF Questionnaire, 35.8% had a risk of
ED. Female gender and treatment with atypical neuroleptics were
significantly associated to ED risk with respectively P = 0.02 and
P = 0.038.
Conclusion Eating disorders remain underestimated among
patients suffering from schizophrenia. Yet, its screening preven-
tion and management are crucial and must be multidisciplinary for
optimal care.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0524
Palatable food access during
adolescence increased BDNF
expression in the nucleus accumbens
and anxiety-/depression-like
behaviors in males, but not in females
J.W. Jahng ∗, J.Y. Kim , J.H. Lee
School of Dentistry, Seoul National University, Dental Research
Institute, Seoul, Republic of Korea
∗ Corresponding author.
Objectives This study was conducted to examine sexual dimor-
phic effects of highly palatable food access during adolescence and
youth on psychoemotional behaviors of rats and its underlying neu-
ral mechanism.
Methods Male and female Sprague Dawley pups had free access
to chocolate cookie rich in fat (highly palatable food) from post-
natal day 28 in addition to ad libitum chow, and the control
groups received chow only. The food conditions were continued
though out the entire experimental period, and the neurochemi-
cal and behavioral measurements were performed during young
adulthood. Corticosterone levels during 2 h of restraint stress were
analyzed with radioimmunoassay, and FosB and brain-derived
neurotrophic factor (BDNF) expression in the nucleus accumbens
(NAc) with western blot analysis.
Results Cookie access did not affect body weight gain and total
caloric intake in both sexes; however, it increased retroperitoneal
fat depot only in males. The time spent in open arms during ele-
vated plus maze test was decreased and immobility during forced
swim test was increased in cookie-fed males, but not in cookie-fed
females. Main effect of food condition on the stress-induced corti-
costerone increase was observed in males, but not in females, and
cookie access increased BDNF expression in the NAc only in males.
Conclusions Increased BDNF expression in the NAc and fat depot,
in addition to the HPA axis dysfunction, may play roles in the patho-
physiology of depression- and/or anxiety-like behaviors induced by
cookie access.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0525
Investigation of food addiction and
impulsivity relations biological
rhythms differences and insomnia in
university students
A. Kandeger ∗, Y. Selvi
Selcuk University, Department of Psychiatry, Konya, Turkey
∗ Corresponding author.
Objective Increasing prevalence of obesity in the world and
increasing role of processed foods in daily life has led to become the
focal point of food addiction. This study aims to investigationof food